ID   Y3564_MYCPA             Reviewed;         313 AA.
AC   Q73U04;
DT   20-JAN-2009, integrated into UniProtKB/Swiss-Prot.
DT   05-JUL-2004, sequence version 1.
DT   03-AUG-2022, entry version 83.
DE   RecName: Full=Putative S-adenosyl-L-methionine-dependent methyltransferase MAP_3564;
DE            EC=2.1.1.-;
GN   OrderedLocusNames=MAP_3564;
OS   Mycolicibacterium paratuberculosis (strain ATCC BAA-968 / K-10)
OS   (Mycobacterium paratuberculosis).
OC   Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC   Mycobacterium; Mycobacterium avium complex (MAC).
OX   NCBI_TaxID=262316;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC BAA-968 / K-10;
RX   PubMed=16116077; DOI=10.1073/pnas.0505662102;
RA   Li L., Bannantine J.P., Zhang Q., Amonsin A., May B.J., Alt D., Banerji N.,
RA   Kanjilal S., Kapur V.;
RT   "The complete genome sequence of Mycobacterium avium subspecies
RT   paratuberculosis.";
RL   Proc. Natl. Acad. Sci. U.S.A. 102:12344-12349(2005).
CC   -!- FUNCTION: Exhibits S-adenosyl-L-methionine-dependent methyltransferase
CC       activity. {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the UPF0677 family. {ECO:0000305}.
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DR   EMBL; AE016958; AAS06114.1; -; Genomic_DNA.
DR   RefSeq; WP_003874205.1; NC_002944.2.
DR   AlphaFoldDB; Q73U04; -.
DR   SMR; Q73U04; -.
DR   STRING; 262316.MAP_3564; -.
DR   EnsemblBacteria; AAS06114; AAS06114; MAP_3564.
DR   KEGG; mpa:MAP_3564; -.
DR   eggNOG; COG3315; Bacteria.
DR   HOGENOM; CLU_056160_2_1_11; -.
DR   OMA; PMDITEL; -.
DR   Proteomes; UP000000580; Chromosome.
DR   GO; GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
DR   GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR   Gene3D; 3.40.50.150; -; 1.
DR   InterPro; IPR011610; CHP00027_methylltransferase.
DR   InterPro; IPR007213; Ppm1/Ppm2/Tcmp.
DR   InterPro; IPR029063; SAM-dependent_MTases_sf.
DR   Pfam; PF04072; LCM; 1.
DR   SUPFAM; SSF53335; SSF53335; 1.
DR   TIGRFAMs; TIGR00027; mthyl_TIGR00027; 1.
PE   3: Inferred from homology;
KW   Methyltransferase; Reference proteome; S-adenosyl-L-methionine;
KW   Transferase.
FT   CHAIN           1..313
FT                   /note="Putative S-adenosyl-L-methionine-dependent
FT                   methyltransferase MAP_3564"
FT                   /id="PRO_0000361181"
FT   BINDING         135
FT                   /ligand="S-adenosyl-L-methionine"
FT                   /ligand_id="ChEBI:CHEBI:59789"
FT                   /evidence="ECO:0000250"
FT   BINDING         164..165
FT                   /ligand="S-adenosyl-L-methionine"
FT                   /ligand_id="ChEBI:CHEBI:59789"
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   313 AA;  34890 MW;  CB4ADA08F371A8FE CRC64;
     MSSLRTHDDT WDIKSSVGTT AVMVAAARAV ETEQPDPLIR DPYAKLLVTN SGAGVLWEAM
     LDPDIAARVE ALDEESAAHL HHMRGYQAVR THFFDTYFAD AVAAGIRQIV ILASGLDSRA
     YRLDWPAGTT VYEIDQPQVL AYKSTTLAEN GVTPSADRRE VAVDLRQDWP AALRAAGFDP
     TQRTAWLAEG LLMYLPAEAQ DRLFTLIGEL SPAGSRVAAE TAPNHADERR QQMRERFKKV
     ADEIGFEQTV DVGELMYRDD HRADVTEWLN AHGWRATAEH STAAMRRLGR WIENVPLADD
     KDAFSDFVVA ERR