ID   Y356_MYCMM              Reviewed;         310 AA.
AC   B2HLS4;
DT   20-JAN-2009, integrated into UniProtKB/Swiss-Prot.
DT   10-JUN-2008, sequence version 1.
DT   03-AUG-2022, entry version 59.
DE   RecName: Full=Putative S-adenosyl-L-methionine-dependent methyltransferase MMAR_0356;
DE            EC=2.1.1.-;
GN   OrderedLocusNames=MMAR_0356;
OS   Mycobacterium marinum (strain ATCC BAA-535 / M).
OC   Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC   Mycobacterium.
OX   NCBI_TaxID=216594;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC BAA-535 / M;
RX   PubMed=18403782; DOI=10.1101/gr.075069.107;
RA   Stinear T.P., Seemann T., Harrison P.F., Jenkin G.A., Davies J.K.,
RA   Johnson P.D., Abdellah Z., Arrowsmith C., Chillingworth T., Churcher C.,
RA   Clarke K., Cronin A., Davis P., Goodhead I., Holroyd N., Jagels K.,
RA   Lord A., Moule S., Mungall K., Norbertczak H., Quail M.A.,
RA   Rabbinowitsch E., Walker D., White B., Whitehead S., Small P.L., Brosch R.,
RA   Ramakrishnan L., Fischbach M.A., Parkhill J., Cole S.T.;
RT   "Insights from the complete genome sequence of Mycobacterium marinum on the
RT   evolution of Mycobacterium tuberculosis.";
RL   Genome Res. 18:729-741(2008).
CC   -!- FUNCTION: Exhibits S-adenosyl-L-methionine-dependent methyltransferase
CC       activity. {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the UPF0677 family. {ECO:0000305}.
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DR   EMBL; CP000854; ACC38823.1; -; Genomic_DNA.
DR   RefSeq; WP_012392338.1; NC_010612.1.
DR   AlphaFoldDB; B2HLS4; -.
DR   SMR; B2HLS4; -.
DR   STRING; 216594.MMAR_0356; -.
DR   EnsemblBacteria; ACC38823; ACC38823; MMAR_0356.
DR   GeneID; 64259121; -.
DR   KEGG; mmi:MMAR_0356; -.
DR   eggNOG; COG3315; Bacteria.
DR   HOGENOM; CLU_056160_2_1_11; -.
DR   OMA; QAVRTHY; -.
DR   OrthoDB; 847145at2; -.
DR   Proteomes; UP000001190; Chromosome.
DR   GO; GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
DR   GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR   Gene3D; 3.40.50.150; -; 1.
DR   InterPro; IPR011610; CHP00027_methylltransferase.
DR   InterPro; IPR007213; Ppm1/Ppm2/Tcmp.
DR   InterPro; IPR029063; SAM-dependent_MTases_sf.
DR   Pfam; PF04072; LCM; 1.
DR   SUPFAM; SSF53335; SSF53335; 1.
DR   TIGRFAMs; TIGR00027; mthyl_TIGR00027; 1.
PE   3: Inferred from homology;
KW   Methyltransferase; Reference proteome; S-adenosyl-L-methionine;
KW   Transferase.
FT   CHAIN           1..310
FT                   /note="Putative S-adenosyl-L-methionine-dependent
FT                   methyltransferase MMAR_0356"
FT                   /id="PRO_0000361168"
FT   BINDING         137
FT                   /ligand="S-adenosyl-L-methionine"
FT                   /ligand_id="ChEBI:CHEBI:59789"
FT                   /evidence="ECO:0000250"
FT   BINDING         166..167
FT                   /ligand="S-adenosyl-L-methionine"
FT                   /ligand_id="ChEBI:CHEBI:59789"
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   310 AA;  34218 MW;  DC8821084E5E8E2A CRC64;
     MTELDEVDSL RSDGDSWTVT ESVGATALGV AAARAVETAG ANPLIRDEFA PILVSSAGPA
     WARLADPDIG WLDDDPHGQR LHRLGCDYQA VRTHFFDEYF AAAAGAGIEQ AVILAAGLDC
     RAYRLNWPPE AVVFEIDQPK VLEYKAQILE SHGVTAAATR HGVAVDLRED WPAALLRAGF
     DRDRPTAWLA EGLLPYLPGD AQDRLFEMIT DLSAPRSRIA VESFTMNLTG NKQRWNRMRD
     RLGLDINVEA LTYREPGRAD AAEWLANHGW QVYSVSNREE MARLGRPVPE DLVDEAITTT
     LLRASLEISR