ID   Y359_STRP1              Reviewed;          80 AA.
AC   P67295; Q490P7; Q9A1B8;
DT   11-OCT-2004, integrated into UniProtKB/Swiss-Prot.
DT   11-OCT-2004, sequence version 1.
DT   25-MAY-2022, entry version 102.
DE   RecName: Full=UPF0154 protein SPy_0359/M5005_Spy0302 {ECO:0000255|HAMAP-Rule:MF_00363};
GN   OrderedLocusNames=SPy_0359, M5005_Spy0302;
OS   Streptococcus pyogenes serotype M1.
OC   Bacteria; Firmicutes; Bacilli; Lactobacillales; Streptococcaceae;
OC   Streptococcus.
OX   NCBI_TaxID=301447;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 700294 / SF370 / Serotype M1;
RX   PubMed=11296296; DOI=10.1073/pnas.071559398;
RA   Ferretti J.J., McShan W.M., Ajdic D.J., Savic D.J., Savic G., Lyon K.,
RA   Primeaux C., Sezate S., Suvorov A.N., Kenton S., Lai H.S., Lin S.P.,
RA   Qian Y., Jia H.G., Najar F.Z., Ren Q., Zhu H., Song L., White J., Yuan X.,
RA   Clifton S.W., Roe B.A., McLaughlin R.E.;
RT   "Complete genome sequence of an M1 strain of Streptococcus pyogenes.";
RL   Proc. Natl. Acad. Sci. U.S.A. 98:4658-4663(2001).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC BAA-947 / MGAS5005 / Serotype M1;
RX   PubMed=16088826; DOI=10.1086/432514;
RA   Sumby P., Porcella S.F., Madrigal A.G., Barbian K.D., Virtaneva K.,
RA   Ricklefs S.M., Sturdevant D.E., Graham M.R., Vuopio-Varkila J., Hoe N.P.,
RA   Musser J.M.;
RT   "Evolutionary origin and emergence of a highly successful clone of serotype
RT   M1 group A Streptococcus involved multiple horizontal gene transfer
RT   events.";
RL   J. Infect. Dis. 192:771-782(2005).
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000255|HAMAP-Rule:MF_00363};
CC       Single-pass membrane protein {ECO:0000255|HAMAP-Rule:MF_00363}.
CC   -!- SIMILARITY: Belongs to the UPF0154 family. {ECO:0000255|HAMAP-
CC       Rule:MF_00363}.
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DR   EMBL; AE004092; AAK33405.1; -; Genomic_DNA.
DR   EMBL; CP000017; AAZ50921.1; -; Genomic_DNA.
DR   RefSeq; NP_268684.1; NC_002737.2.
DR   AlphaFoldDB; P67295; -.
DR   SMR; P67295; -.
DR   STRING; 1314.HKU360_00338; -.
DR   PaxDb; P67295; -.
DR   EnsemblBacteria; AAK33405; AAK33405; SPy_0359.
DR   KEGG; spy:SPy_0359; -.
DR   KEGG; spz:M5005_Spy0302; -.
DR   PATRIC; fig|160490.10.peg.310; -.
DR   HOGENOM; CLU_180108_0_0_9; -.
DR   OMA; PISEEMM; -.
DR   Proteomes; UP000000750; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-UniRule.
DR   HAMAP; MF_00363; UPF0154; 1.
DR   InterPro; IPR005359; UPF0154.
DR   Pfam; PF03672; UPF0154; 1.
PE   3: Inferred from homology;
KW   Membrane; Reference proteome; Transmembrane; Transmembrane helix.
FT   CHAIN           1..80
FT                   /note="UPF0154 protein SPy_0359/M5005_Spy0302"
FT                   /id="PRO_0000214988"
FT   TRANSMEM        4..24
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00363"
SQ   SEQUENCE   80 AA;  8894 MW;  AB2A53DD115F140A CRC64;
     MSTAIWILLL IVALGVGVFG GIFIARKQIE KEIGEHPRLT PEAIREMMSQ MGQKPSEAKI
     QQTYRNIIKQ SKAAVSKGKK