ID   CARD_PECCC              Reviewed;         376 AA.
AC   Q9XB58;
DT   30-MAY-2000, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1999, sequence version 1.
DT   25-MAY-2022, entry version 50.
DE   RecName: Full=Carbapenem antibiotics biosynthesis protein CarD;
GN   Name=carD;
OS   Pectobacterium carotovorum subsp. carotovorum (Erwinia carotovora subsp.
OS   carotovora).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Pectobacteriaceae; Pectobacterium.
OX   NCBI_TaxID=555;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=ATCC 39048 / GS101 / SC 12;
RX   PubMed=9402024; DOI=10.1046/j.1365-2958.1997.6001974.x;
RA   McGowan S.J., Sebaihia M., O'Leary S., Hardie K.R., Williams P.,
RA   Stewart G.S., Bycroft B.W., Salmond G.P.;
RT   "Analysis of the carbapenem gene cluster of Erwinia carotovora: definition
RT   of the antibiotic biosynthetic genes and evidence for a novel beta-lactam
RT   resistance mechanism.";
RL   Mol. Microbiol. 26:545-556(1997).
CC   -!- PATHWAY: Antibiotic biosynthesis; carbapenem biosynthesis.
CC   -!- SIMILARITY: Belongs to the proline oxidase family. {ECO:0000305}.
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DR   EMBL; U17224; AAD38232.1; -; Genomic_DNA.
DR   AlphaFoldDB; Q9XB58; -.
DR   SMR; Q9XB58; -.
DR   UniPathway; UPA00182; -.
DR   GO; GO:0004657; F:proline dehydrogenase activity; IEA:InterPro.
DR   GO; GO:0017000; P:antibiotic biosynthetic process; IEA:UniProtKB-KW.
DR   GO; GO:0006562; P:proline catabolic process; IEA:InterPro.
DR   InterPro; IPR029041; FAD-linked_oxidoreductase-like.
DR   InterPro; IPR002872; Proline_DH_dom.
DR   InterPro; IPR015659; Proline_oxidase.
DR   PANTHER; PTHR13914; PTHR13914; 1.
DR   Pfam; PF01619; Pro_dh; 1.
DR   SUPFAM; SSF51730; SSF51730; 1.
PE   3: Inferred from homology;
KW   Antibiotic biosynthesis; Oxidoreductase.
FT   CHAIN           1..376
FT                   /note="Carbapenem antibiotics biosynthesis protein CarD"
FT                   /id="PRO_0000174214"
SQ   SEQUENCE   376 AA;  42885 MW;  1F8AF5AE7733DE7C CRC64;
     MPNDLYAIYN RYTSRTLFFK YCATATLTHR LTRRLSLFTL KKCLARPQGR LFSLVNSIYF
     GGETLEEVQS TATFLARSGI ACVLDYAVEG ENDETQFDKA MENTLRLIEM SQQTDSLPFV
     VIKPSSLGSV AVYARQSERL ALDEASASAW SRIVTRFSRL FDYARSHGVH VMVDAEQTAI
     QPAVDRLVLD MMREFNRDSA VITLTLQFYL KDQLRFLDEC YQRACQDNFL FGVKVVRGAY
     LEEEKRVNGG VRCFATKQET DRSYNAAVDY IALRLDRIAP FFATHNEESL ALIMSSESLR
     AGRTWVGQLY GLGDHITYSL LQTGFRVCKY LPYGPLDKSL PYLLRRIEEN AVASATFKKE
     NKLLQKELLR RLVGGM