Y3660_MYCTO
ID Y3660_MYCTO Reviewed; 350 AA.
AC P9WKX6; L0TD64; O69628; Q7D546;
DT 16-APR-2014, integrated into UniProtKB/Swiss-Prot.
DT 16-APR-2014, sequence version 1.
DT 25-MAY-2022, entry version 38.
DE RecName: Full=Uncharacterized protein MT3760;
GN OrderedLocusNames=MT3760;
OS Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh).
OC Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC Mycobacterium; Mycobacterium tuberculosis complex.
OX NCBI_TaxID=83331;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CDC 1551 / Oshkosh;
RX PubMed=12218036; DOI=10.1128/jb.184.19.5479-5490.2002;
RA Fleischmann R.D., Alland D., Eisen J.A., Carpenter L., White O.,
RA Peterson J.D., DeBoy R.T., Dodson R.J., Gwinn M.L., Haft D.H., Hickey E.K.,
RA Kolonay J.F., Nelson W.C., Umayam L.A., Ermolaeva M.D., Salzberg S.L.,
RA Delcher A., Utterback T.R., Weidman J.F., Khouri H.M., Gill J., Mikula A.,
RA Bishai W., Jacobs W.R. Jr., Venter J.C., Fraser C.M.;
RT "Whole-genome comparison of Mycobacterium tuberculosis clinical and
RT laboratory strains.";
RL J. Bacteriol. 184:5479-5490(2002).
RN [2]
RP DISRUPTION PHENOTYPE.
RC STRAIN=CDC 1551 / Oshkosh;
RX PubMed=12775759; DOI=10.1073/pnas.1231432100;
RA Lamichhane G., Zignol M., Blades N.J., Geiman D.E., Dougherty A.,
RA Grosset J., Broman K.W., Bishai W.R.;
RT "A postgenomic method for predicting essential genes at subsaturation
RT levels of mutagenesis: application to Mycobacterium tuberculosis.";
RL Proc. Natl. Acad. Sci. U.S.A. 100:7213-7218(2003).
CC -!- FUNCTION: May play a role in septum formation. {ECO:0000250}.
CC -!- DISRUPTION PHENOTYPE: Not essential for growth.
CC {ECO:0000269|PubMed:12775759}.
CC -!- SEQUENCE CAUTION:
CC Sequence=AAK48124.1; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR EMBL; AE000516; AAK48124.1; ALT_INIT; Genomic_DNA.
DR PIR; E70788; E70788.
DR RefSeq; WP_003900732.1; NZ_KK341227.1.
DR AlphaFoldDB; P9WKX6; -.
DR SMR; P9WKX6; -.
DR EnsemblBacteria; AAK48124; AAK48124; MT3760.
DR KEGG; mtc:MT3760; -.
DR PATRIC; fig|83331.31.peg.4049; -.
DR HOGENOM; CLU_082953_0_0_11; -.
DR Proteomes; UP000001020; Chromosome.
DR Gene3D; 3.40.50.300; -; 1.
DR InterPro; IPR022521; CHP03815_CpaE-like.
DR InterPro; IPR027417; P-loop_NTPase.
DR SUPFAM; SSF52540; SSF52540; 1.
DR TIGRFAMs; TIGR03815; CpaE_hom_Actino; 1.
PE 3: Inferred from homology;
FT CHAIN 1..350
FT /note="Uncharacterized protein MT3760"
FT /id="PRO_0000427577"
SQ SEQUENCE 350 AA; 35807 MW; 1FEA7D40836322CD CRC64;
MLTDPGLRDE LDRVAAAVGV RVVHLGGRHP VSRKTWSAAA AVVLDHAAAD RCGRLALPRR
THVSVLTGTE AATATWAAAI TVGAQHVLRM PEQEGELVRE LAEAAESARD DGICGAVVAV
IGGRGGAGAS LFAVALAQAA ADALLVDLDP WAGGIDLLVG GETAPGLRWP DLALQGGRLN
WSAVRAALPR PRGISVLSGT RRGYELDAGP VDAVIDAGRR GGVTVVCDLP RRLTDATQAA
LDAADLVVLV SPCDVRACAA AATMAPVLTA INPNLGLVVR GPSPGGLRAA EVADVAGVPL
LASMRAQPRL AEQLEHGGLR LRRRSVLASA ARRVLGVLPR AGSGRHGRAA