ID   Y368_LISMO              Reviewed;         169 AA.
AC   Q8Y9Z9;
DT   10-JAN-2003, integrated into UniProtKB/Swiss-Prot.
DT   01-MAR-2002, sequence version 1.
DT   03-AUG-2022, entry version 92.
DE   RecName: Full=Uncharacterized Nudix hydrolase lmo0368;
DE            EC=3.6.-.-;
GN   OrderedLocusNames=lmo0368;
OS   Listeria monocytogenes serovar 1/2a (strain ATCC BAA-679 / EGD-e).
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Listeriaceae; Listeria.
OX   NCBI_TaxID=169963;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC BAA-679 / EGD-e;
RX   PubMed=11679669; DOI=10.1126/science.1063447;
RA   Glaser P., Frangeul L., Buchrieser C., Rusniok C., Amend A., Baquero F.,
RA   Berche P., Bloecker H., Brandt P., Chakraborty T., Charbit A.,
RA   Chetouani F., Couve E., de Daruvar A., Dehoux P., Domann E.,
RA   Dominguez-Bernal G., Duchaud E., Durant L., Dussurget O., Entian K.-D.,
RA   Fsihi H., Garcia-del Portillo F., Garrido P., Gautier L., Goebel W.,
RA   Gomez-Lopez N., Hain T., Hauf J., Jackson D., Jones L.-M., Kaerst U.,
RA   Kreft J., Kuhn M., Kunst F., Kurapkat G., Madueno E., Maitournam A.,
RA   Mata Vicente J., Ng E., Nedjari H., Nordsiek G., Novella S., de Pablos B.,
RA   Perez-Diaz J.-C., Purcell R., Remmel B., Rose M., Schlueter T., Simoes N.,
RA   Tierrez A., Vazquez-Boland J.-A., Voss H., Wehland J., Cossart P.;
RT   "Comparative genomics of Listeria species.";
RL   Science 294:849-852(2001).
CC   -!- COFACTOR:
CC       Name=Mg(2+); Xref=ChEBI:CHEBI:18420; Evidence={ECO:0000250};
CC   -!- SIMILARITY: Belongs to the Nudix hydrolase family. {ECO:0000305}.
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DR   EMBL; AL591975; CAC98447.1; -; Genomic_DNA.
DR   PIR; AI1120; AI1120.
DR   RefSeq; NP_463898.1; NC_003210.1.
DR   RefSeq; WP_009914285.1; NZ_CP023861.1.
DR   AlphaFoldDB; Q8Y9Z9; -.
DR   SMR; Q8Y9Z9; -.
DR   STRING; 169963.lmo0368; -.
DR   PaxDb; Q8Y9Z9; -.
DR   EnsemblBacteria; CAC98447; CAC98447; CAC98447.
DR   GeneID; 987618; -.
DR   KEGG; lmo:lmo0368; -.
DR   PATRIC; fig|169963.11.peg.380; -.
DR   eggNOG; COG1443; Bacteria.
DR   HOGENOM; CLU_060552_1_1_9; -.
DR   OMA; HIVIHAW; -.
DR   PhylomeDB; Q8Y9Z9; -.
DR   BioCyc; LMON169963:LMO0368-MON; -.
DR   Proteomes; UP000000817; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR   GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR   GO; GO:0004452; F:isopentenyl-diphosphate delta-isomerase activity; IBA:GO_Central.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0009240; P:isopentenyl diphosphate biosynthetic process; IBA:GO_Central.
DR   InterPro; IPR015797; NUDIX_hydrolase-like_dom_sf.
DR   InterPro; IPR020084; NUDIX_hydrolase_CS.
DR   InterPro; IPR000086; NUDIX_hydrolase_dom.
DR   Pfam; PF00293; NUDIX; 1.
DR   SUPFAM; SSF55811; SSF55811; 1.
DR   PROSITE; PS51462; NUDIX; 1.
DR   PROSITE; PS00893; NUDIX_BOX; 1.
PE   3: Inferred from homology;
KW   Hydrolase; Magnesium; Metal-binding; Reference proteome.
FT   CHAIN           1..169
FT                   /note="Uncharacterized Nudix hydrolase lmo0368"
FT                   /id="PRO_0000057084"
FT   DOMAIN          28..157
FT                   /note="Nudix hydrolase"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00794"
FT   MOTIF           65..87
FT                   /note="Nudix box"
FT   BINDING         81
FT                   /ligand="Mg(2+)"
FT                   /ligand_id="ChEBI:CHEBI:18420"
FT                   /evidence="ECO:0000250"
FT   BINDING         85
FT                   /ligand="Mg(2+)"
FT                   /ligand_id="ChEBI:CHEBI:18420"
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   169 AA;  19600 MW;  F45F2A780EECD95E CRC64;
     MEEWDLLNEN RELTGKTHIR GEKLAPGELH LVIHVCIFNE KGQLLIQKRQ KDKEGWPNYW
     DLSAAGSALK GETSQQAAER EVQEELGIMI DLSGTRAKFS YHFEEGFDDY WFITKDVQLS
     DLTLQKEEVA DARFVTKEEL EALRSSGEFI PYFFLNQLFN LKNATTIHF