ID   Y3691_MYCTU             Reviewed;         381 AA.
AC   O69659; L0TGG4;
DT   22-FEB-2012, integrated into UniProtKB/Swiss-Prot.
DT   22-FEB-2012, sequence version 4.
DT   25-MAY-2022, entry version 97.
DE   RecName: Full=Uncharacterized membrane protein Rv3691;
GN   OrderedLocusNames=Rv3691;
OS   Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv).
OC   Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC   Mycobacterium; Mycobacterium tuberculosis complex.
OX   NCBI_TaxID=83332;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 25618 / H37Rv;
RX   PubMed=9634230; DOI=10.1038/31159;
RA   Cole S.T., Brosch R., Parkhill J., Garnier T., Churcher C.M., Harris D.E.,
RA   Gordon S.V., Eiglmeier K., Gas S., Barry C.E. III, Tekaia F., Badcock K.,
RA   Basham D., Brown D., Chillingworth T., Connor R., Davies R.M., Devlin K.,
RA   Feltwell T., Gentles S., Hamlin N., Holroyd S., Hornsby T., Jagels K.,
RA   Krogh A., McLean J., Moule S., Murphy L.D., Oliver S., Osborne J.,
RA   Quail M.A., Rajandream M.A., Rogers J., Rutter S., Seeger K., Skelton S.,
RA   Squares S., Squares R., Sulston J.E., Taylor K., Whitehead S.,
RA   Barrell B.G.;
RT   "Deciphering the biology of Mycobacterium tuberculosis from the complete
RT   genome sequence.";
RL   Nature 393:537-544(1998).
RN   [2]
RP   IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RC   STRAIN=ATCC 25618 / H37Rv;
RX   PubMed=21969609; DOI=10.1074/mcp.m111.011627;
RA   Kelkar D.S., Kumar D., Kumar P., Balakrishnan L., Muthusamy B., Yadav A.K.,
RA   Shrivastava P., Marimuthu A., Anand S., Sundaram H., Kingsbury R.,
RA   Harsha H.C., Nair B., Prasad T.S., Chauhan D.S., Katoch K., Katoch V.M.,
RA   Kumar P., Chaerkady R., Ramachandran S., Dash D., Pandey A.;
RT   "Proteogenomic analysis of Mycobacterium tuberculosis by high resolution
RT   mass spectrometry.";
RL   Mol. Cell. Proteomics 10:M111.011627-M111.011627(2011).
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=CCP46515.1; Type=Erroneous initiation; Note=Truncated N-terminus.; Evidence={ECO:0000305};
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DR   EMBL; AL123456; CCP46515.1; ALT_INIT; Genomic_DNA.
DR   PIR; D70792; D70792.
DR   RefSeq; NP_218208.1; NC_000962.3.
DR   RefSeq; WP_003899642.1; NC_018143.2.
DR   AlphaFoldDB; O69659; -.
DR   STRING; 83332.Rv3691; -.
DR   PaxDb; O69659; -.
DR   GeneID; 885623; -.
DR   KEGG; mtu:Rv3691; -.
DR   PATRIC; fig|83332.12.peg.4114; -.
DR   TubercuList; Rv3691; -.
DR   eggNOG; ENOG502ZY4N; Bacteria.
DR   InParanoid; O69659; -.
DR   Proteomes; UP000001584; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; HDA:MTBBASE.
DR   InterPro; IPR025646; DUF4350.
DR   Pfam; PF14258; DUF4350; 1.
PE   1: Evidence at protein level;
KW   Cell membrane; Membrane; Reference proteome; Transmembrane;
KW   Transmembrane helix.
FT   CHAIN           1..381
FT                   /note="Uncharacterized membrane protein Rv3691"
FT                   /id="PRO_0000415511"
FT   TRANSMEM        22..42
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        246..266
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   381 AA;  40442 MW;  A0924C15DA853F3F CRC64;
     MGAGPVIPTR LATVRRRRPW RGVLLTLAAV AVVASIGTYL TAPRPGGAMA PASTSSTGGH
     ALATLLGNHG VEVVVADSIA DVEAAARPDS LLLVAQTQYL VDNALLDRLA KAPGDLLLVA
     PTSRTRTALT PQLRIAAASP FNSQPNCTLR EANRAGSVQW GPSDTYQATG DLVLTSCYGG
     ALVRFRAEGR TITVVGSSNF MTNGGLLPAG NAALAMNLAG NRPRLVWYAP DHIEGEMSSP
     SSLSDLIPEN VHWTIWQLWL VVLLVALWKG RRIGPLVAEE LPVVIRASET VEGRGRLYRS
     RRARDRAADA LRTATLQRLR PRLGVGAGAP APAVVTTIAQ RSKADPPFVA YHLFGPAPAT
     DNDLLQLARA LDDIERQVTH S