ID   Y3746_DICDI             Reviewed;         395 AA.
AC   Q54BD1;
DT   10-FEB-2009, integrated into UniProtKB/Swiss-Prot.
DT   24-MAY-2005, sequence version 1.
DT   03-AUG-2022, entry version 78.
DE   RecName: Full=Probable inactive serine/threonine-protein kinase DDB_G0293746;
GN   ORFNames=DDB_G0293746;
OS   Dictyostelium discoideum (Slime mold).
OC   Eukaryota; Amoebozoa; Evosea; Eumycetozoa; Dictyostelia; Dictyosteliales;
OC   Dictyosteliaceae; Dictyostelium.
OX   NCBI_TaxID=44689;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=AX4;
RX   PubMed=15875012; DOI=10.1038/nature03481;
RA   Eichinger L., Pachebat J.A., Gloeckner G., Rajandream M.A., Sucgang R.,
RA   Berriman M., Song J., Olsen R., Szafranski K., Xu Q., Tunggal B.,
RA   Kummerfeld S., Madera M., Konfortov B.A., Rivero F., Bankier A.T.,
RA   Lehmann R., Hamlin N., Davies R., Gaudet P., Fey P., Pilcher K., Chen G.,
RA   Saunders D., Sodergren E.J., Davis P., Kerhornou A., Nie X., Hall N.,
RA   Anjard C., Hemphill L., Bason N., Farbrother P., Desany B., Just E.,
RA   Morio T., Rost R., Churcher C.M., Cooper J., Haydock S., van Driessche N.,
RA   Cronin A., Goodhead I., Muzny D.M., Mourier T., Pain A., Lu M., Harper D.,
RA   Lindsay R., Hauser H., James K.D., Quiles M., Madan Babu M., Saito T.,
RA   Buchrieser C., Wardroper A., Felder M., Thangavelu M., Johnson D.,
RA   Knights A., Loulseged H., Mungall K.L., Oliver K., Price C., Quail M.A.,
RA   Urushihara H., Hernandez J., Rabbinowitsch E., Steffen D., Sanders M.,
RA   Ma J., Kohara Y., Sharp S., Simmonds M.N., Spiegler S., Tivey A.,
RA   Sugano S., White B., Walker D., Woodward J.R., Winckler T., Tanaka Y.,
RA   Shaulsky G., Schleicher M., Weinstock G.M., Rosenthal A., Cox E.C.,
RA   Chisholm R.L., Gibbs R.A., Loomis W.F., Platzer M., Kay R.R.,
RA   Williams J.G., Dear P.H., Noegel A.A., Barrell B.G., Kuspa A.;
RT   "The genome of the social amoeba Dictyostelium discoideum.";
RL   Nature 435:43-57(2005).
CC   -!- DOMAIN: The protein kinase domain is predicted to be catalytically
CC       inactive.
CC   -!- SIMILARITY: Belongs to the protein kinase superfamily. Ser/Thr protein
CC       kinase family. {ECO:0000255|PROSITE-ProRule:PRU00159}.
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DR   EMBL; AAFI02000219; EAL60550.1; -; Genomic_DNA.
DR   RefSeq; XP_628963.1; XM_628961.1.
DR   AlphaFoldDB; Q54BD1; -.
DR   STRING; 44689.DDB0229346; -.
DR   PaxDb; Q54BD1; -.
DR   EnsemblProtists; EAL60550; EAL60550; DDB_G0293746.
DR   GeneID; 8629391; -.
DR   KEGG; ddi:DDB_G0293746; -.
DR   dictyBase; DDB_G0293746; -.
DR   eggNOG; ENOG502REWG; Eukaryota.
DR   HOGENOM; CLU_699139_0_0_1; -.
DR   InParanoid; Q54BD1; -.
DR   OMA; RRKCKGS; -.
DR   PRO; PR:Q54BD1; -.
DR   Proteomes; UP000002195; Chromosome 6.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004672; F:protein kinase activity; IEA:InterPro.
DR   GO; GO:0006468; P:protein phosphorylation; IEA:InterPro.
DR   InterPro; IPR011009; Kinase-like_dom_sf.
DR   InterPro; IPR000719; Prot_kinase_dom.
DR   Pfam; PF00069; Pkinase; 1.
DR   SMART; SM00220; S_TKc; 1.
DR   SUPFAM; SSF56112; SSF56112; 1.
DR   PROSITE; PS50011; PROTEIN_KINASE_DOM; 1.
PE   3: Inferred from homology;
KW   ATP-binding; Nucleotide-binding; Reference proteome.
FT   CHAIN           1..395
FT                   /note="Probable inactive serine/threonine-protein kinase
FT                   DDB_G0293746"
FT                   /id="PRO_0000362052"
FT   DOMAIN          9..395
FT                   /note="Protein kinase"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00159"
FT   REGION          213..266
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   BINDING         15..23
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00159"
FT   BINDING         54
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00159"
SQ   SEQUENCE   395 AA;  45442 MW;  FEDE251926B4A648 CRC64;
     MNENSISQYS EIDLISDNPF KNYFVVEKLL NNNNNNINDT IGNNHYSNNN NNNKFLNNNN
     KNKINKKQII LKVQKKSNKA MKELTVMQKI GYYSNHVVNV YGYFNLKGCD RMLKPRLLSD
     NDELIFMECE DMGQYQTLEM IIERRKCKGS LVMTRFIMRG ILASAYYFES HQVIHQTLHP
     GNIYILEDSL GTDDQSVVKF SNLEHCLLIG STNSSLSSLS SSTSSSSSSS SSTNCNNNTT
     ENNNNNYNNN NNNNNNNNNN NNNNSLNDRF VLGKDSVCYS IYSDRHQSRN LFKVVSSNTV
     SFTVGIIYLE LLLSTIYDHV FPNEEYINSL REIVRNGKLD IYTNQATNTK YFRFNQNHQI
     EITDLIKDDI SLILTLLQDS STRPTITQFI IDYLF