ID   Y374_TREPA              Reviewed;         791 AA.
AC   O83389;
DT   01-JUN-2001, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1998, sequence version 1.
DT   25-MAY-2022, entry version 95.
DE   RecName: Full=Uncharacterized protein TP_0374;
GN   OrderedLocusNames=TP_0374;
OS   Treponema pallidum (strain Nichols).
OC   Bacteria; Spirochaetes; Spirochaetales; Treponemataceae; Treponema.
OX   NCBI_TaxID=243276;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Nichols;
RX   PubMed=9665876; DOI=10.1126/science.281.5375.375;
RA   Fraser C.M., Norris S.J., Weinstock G.M., White O., Sutton G.G.,
RA   Dodson R.J., Gwinn M.L., Hickey E.K., Clayton R.A., Ketchum K.A.,
RA   Sodergren E., Hardham J.M., McLeod M.P., Salzberg S.L., Peterson J.D.,
RA   Khalak H.G., Richardson D.L., Howell J.K., Chidambaram M., Utterback T.R.,
RA   McDonald L.A., Artiach P., Bowman C., Cotton M.D., Fujii C., Garland S.A.,
RA   Hatch B., Horst K., Roberts K.M., Sandusky M., Weidman J.F., Smith H.O.,
RA   Venter J.C.;
RT   "Complete genome sequence of Treponema pallidum, the syphilis spirochete.";
RL   Science 281:375-388(1998).
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DR   EMBL; AE000520; AAC65362.1; -; Genomic_DNA.
DR   PIR; E71333; E71333.
DR   RefSeq; WP_010881822.1; NC_021490.2.
DR   AlphaFoldDB; O83389; -.
DR   SMR; O83389; -.
DR   IntAct; O83389; 7.
DR   STRING; 243276.TPANIC_0374; -.
DR   EnsemblBacteria; AAC65362; AAC65362; TP_0374.
DR   KEGG; tpa:TP_0374; -.
DR   eggNOG; COG0457; Bacteria.
DR   HOGENOM; CLU_392278_0_0_12; -.
DR   OMA; YETHEPI; -.
DR   OrthoDB; 1014561at2; -.
DR   Proteomes; UP000000811; Chromosome.
DR   Gene3D; 1.25.40.10; -; 1.
DR   InterPro; IPR011990; TPR-like_helical_dom_sf.
DR   SUPFAM; SSF48452; SSF48452; 1.
PE   4: Predicted;
KW   Reference proteome.
FT   CHAIN           1..791
FT                   /note="Uncharacterized protein TP_0374"
FT                   /id="PRO_0000202244"
FT   REGION          267..288
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        268..286
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   791 AA;  89452 MW;  FD1D1ABD59ED2D34 CRC64;
     MRSMAQHLVT KIVTRRGLLM SKGMCPRMGR LCAVSIFCAF SGIQDASCVS EPAPPQDLER
     NHPGVAARYL QEGRWQEALS QAEQGVASAP QIADFLFIAA RASYALQQPR ARALQWMARA
     VAKDMQWCVY DIEEVRLFYA RLCVDTLQHA RALELLATAE QVSADADWLR ARARYGLGQV
     EHAQELIEKA LERWALDARF AKLFFAQERS RRPSSRSKKI ADSILSRLSV WQEQDPSLLV
     EAALFEPRTN MAFRYLQTYF TLRPLDAPGE SSAQSSYEQS TRAGDSAPEQ ELYARAQSIV
     LGLQYGVLDE QRAMEMFCTL NSPLAVPAVD PTDDVSSFGV HASSVSSSTP LQRVVVLYAD
     LLHEFSRLLA SRPIRARFAR FLAEFEGVLY TDENRDGIVS ARVFFKAGRP SRAQFDTNQD
     GILEYEVYAN DGAPTCVHTM HSTQKTELSR ASVFPIPQNI AAHDHERAAE RWIAPRVSLP
     ADNGVEGETQ ARVPLTQQGY RVCYDRYPEV HQVGWEDKTY VLRPRALRWQ PVRMQSLDLA
     RDLEGVRSHD FFTMVLTNEP LPTEQQITVS SLYYEKPDSL FERARVRTYL DEGLPLFSET
     HVGSRFRART HYVDGRATRR DSDRDDDGFF ETREYYNAQG AVRALSVDVH KDRSFAYQEE
     YGAKGQKVQK WYGRGRVTIS HTELPTGHAR TEWLHPVTGR HVTVDFVQGV PKRLLVDGEV
     HALTKDPRNA ALYWVRRIPR NGDEVGQRIV ESFRAATSPV VSEYFRTGGS VVRAVRSGGV
     VFAEELEPGK E