ID   Y3753_MYCTA             Reviewed;         133 AA.
AC   A5U942;
DT   15-JAN-2008, integrated into UniProtKB/Swiss-Prot.
DT   10-JUL-2007, sequence version 1.
DT   25-MAY-2022, entry version 76.
DE   RecName: Full=Nucleoid-associated protein MRA_3753 {ECO:0000255|HAMAP-Rule:MF_00274};
GN   OrderedLocusNames=MRA_3753;
OS   Mycobacterium tuberculosis (strain ATCC 25177 / H37Ra).
OC   Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC   Mycobacterium; Mycobacterium tuberculosis complex.
OX   NCBI_TaxID=419947;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 25177 / H37Ra;
RX   PubMed=18584054; DOI=10.1371/journal.pone.0002375;
RA   Zheng H., Lu L., Wang B., Pu S., Zhang X., Zhu G., Shi W., Zhang L.,
RA   Wang H., Wang S., Zhao G., Zhang Y.;
RT   "Genetic basis of virulence attenuation revealed by comparative genomic
RT   analysis of Mycobacterium tuberculosis strain H37Ra versus H37Rv.";
RL   PLoS ONE 3:E2375-E2375(2008).
CC   -!- FUNCTION: Binds to DNA and alters its conformation. May be involved in
CC       regulation of gene expression, nucleoid organization and DNA
CC       protection. {ECO:0000255|HAMAP-Rule:MF_00274}.
CC   -!- SUBUNIT: Homodimer. {ECO:0000255|HAMAP-Rule:MF_00274}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm, nucleoid {ECO:0000255|HAMAP-
CC       Rule:MF_00274}.
CC   -!- SIMILARITY: Belongs to the YbaB/EbfC family. {ECO:0000255|HAMAP-
CC       Rule:MF_00274}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; CP000611; ABQ75542.1; -; Genomic_DNA.
DR   RefSeq; WP_003420408.1; NZ_CP016972.1.
DR   AlphaFoldDB; A5U942; -.
DR   SMR; A5U942; -.
DR   STRING; 419947.MRA_3753; -.
DR   EnsemblBacteria; ABQ75542; ABQ75542; MRA_3753.
DR   GeneID; 45427715; -.
DR   KEGG; mra:MRA_3753; -.
DR   eggNOG; COG0718; Bacteria.
DR   HOGENOM; CLU_140930_4_0_11; -.
DR   OMA; MGNMMKQ; -.
DR   OrthoDB; 1883809at2; -.
DR   Proteomes; UP000001988; Chromosome.
DR   GO; GO:0043590; C:bacterial nucleoid; IEA:UniProtKB-UniRule.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-UniRule.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR   Gene3D; 3.30.1310.10; -; 1.
DR   HAMAP; MF_00274; DNA_YbaB_EbfC; 1.
DR   InterPro; IPR036894; YbaB-like_sf.
DR   InterPro; IPR004401; YbaB/EbfC.
DR   PANTHER; PTHR33449; PTHR33449; 1.
DR   Pfam; PF02575; YbaB_DNA_bd; 1.
DR   PIRSF; PIRSF004555; UCP004555; 1.
DR   SUPFAM; SSF82607; SSF82607; 1.
DR   TIGRFAMs; TIGR00103; DNA_YbaB_EbfC; 1.
PE   3: Inferred from homology;
KW   Cytoplasm; DNA-binding.
FT   CHAIN           1..133
FT                   /note="Nucleoid-associated protein MRA_3753"
FT                   /id="PRO_1000003779"
FT   REGION          98..133
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        102..133
FT                   /note="Pro residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   133 AA;  13357 MW;  9D689EE3170AE782 CRC64;
     MQPGGDMSAL LAQAQQMQQK LLEAQQQLAN SEVHGQAGGG LVKVVVKGSG EVIGVTIDPK
     VVDPDDIETL QDLIVGAMRD ASQQVTKMAQ ERLGALAGAM RPPAPPAAPP GAPGMPGMPG
     MPGAPGAPPV PGI