ID   Y376_AQUAE              Reviewed;         313 AA.
AC   O66698;
DT   11-JUL-2001, integrated into UniProtKB/Swiss-Prot.
DT   01-AUG-1998, sequence version 1.
DT   03-AUG-2022, entry version 86.
DE   RecName: Full=Uncharacterized protein aq_376;
GN   OrderedLocusNames=aq_376;
OS   Aquifex aeolicus (strain VF5).
OC   Bacteria; Aquificae; Aquificales; Aquificaceae; Aquifex.
OX   NCBI_TaxID=224324;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=VF5;
RX   PubMed=9537320; DOI=10.1038/32831;
RA   Deckert G., Warren P.V., Gaasterland T., Young W.G., Lenox A.L.,
RA   Graham D.E., Overbeek R., Snead M.A., Keller M., Aujay M., Huber R.,
RA   Feldman R.A., Short J.M., Olsen G.J., Swanson R.V.;
RT   "The complete genome of the hyperthermophilic bacterium Aquifex aeolicus.";
RL   Nature 392:353-358(1998).
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
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DR   EMBL; AE000657; AAC06659.1; -; Genomic_DNA.
DR   PIR; F70333; F70333.
DR   RefSeq; NP_213258.1; NC_000918.1.
DR   RefSeq; WP_010880196.1; NC_000918.1.
DR   AlphaFoldDB; O66698; -.
DR   STRING; 224324.aq_376; -.
DR   EnsemblBacteria; AAC06659; AAC06659; aq_376.
DR   KEGG; aae:aq_376; -.
DR   eggNOG; ENOG5032YUE; Bacteria.
DR   HOGENOM; CLU_887530_0_0_0; -.
DR   Proteomes; UP000000798; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
PE   4: Predicted;
KW   Cell membrane; Membrane; Reference proteome; Transmembrane;
KW   Transmembrane helix.
FT   CHAIN           1..313
FT                   /note="Uncharacterized protein aq_376"
FT                   /id="PRO_0000186856"
FT   TRANSMEM        19..41
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        51..68
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        81..103
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   313 AA;  35705 MW;  3AFB57ADA036711A CRC64;
     MEGIKVLAKQ FGKIKTPQGL AVAIALITAI AWFPDGLAGF LPSLKSNPFQ AIIGAILTIL
     GLSIIFFLHK KLRRGQKDSI IAEFGFIVLT LIFSLIVFND FAITQFITSS LVFFSAWLHV
     REMEIVDYTV REVRPSNVKA TVIFLSSAKY DEKFKKLMEK VEEIPTINDF FDFLEKEKMR
     LPWEMQLRLI NEFSRSLKYV YVIGSVNSSS GSFEQIEDFK LIVNKFFPQI EVIKYREGLD
     FENLEKNFGV LKEIYSELKT KGLKEREIII DTTGGQKIQS IAGALYSTAY DRFFAYVSTN
     SKSVKVFDVV PTE