ID   Y3787_VIBC3             Reviewed;         162 AA.
AC   A5F419; C3M386;
DT   26-FEB-2008, integrated into UniProtKB/Swiss-Prot.
DT   12-JUN-2007, sequence version 1.
DT   25-MAY-2022, entry version 68.
DE   RecName: Full=UPF0114 protein VC0395_A2587/VC395_0240 {ECO:0000255|HAMAP-Rule:MF_00143};
GN   OrderedLocusNames=VC0395_A2587, VC395_0240;
OS   Vibrio cholerae serotype O1 (strain ATCC 39541 / Classical Ogawa 395 /
OS   O395).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Vibrionales; Vibrionaceae;
OC   Vibrio.
OX   NCBI_TaxID=345073;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 39541 / Classical Ogawa 395 / O395;
RA   Heidelberg J.;
RL   Submitted (MAR-2007) to the EMBL/GenBank/DDBJ databases.
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 39541 / Classical Ogawa 395 / O395;
RX   PubMed=19115014; DOI=10.1371/journal.pone.0004053;
RA   Feng L., Reeves P.R., Lan R., Ren Y., Gao C., Zhou Z., Ren Y., Cheng J.,
RA   Wang W., Wang J., Qian W., Li D., Wang L.;
RT   "A recalibrated molecular clock and independent origins for the cholera
RT   pandemic clones.";
RL   PLoS ONE 3:E4053-E4053(2008).
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000255|HAMAP-Rule:MF_00143};
CC       Multi-pass membrane protein {ECO:0000255|HAMAP-Rule:MF_00143}.
CC   -!- SIMILARITY: Belongs to the UPF0114 family. {ECO:0000255|HAMAP-
CC       Rule:MF_00143}.
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DR   EMBL; CP000627; ABQ21510.1; -; Genomic_DNA.
DR   EMBL; CP001235; ACP08265.1; -; Genomic_DNA.
DR   RefSeq; WP_000440285.1; NZ_JAACZH010000031.1.
DR   AlphaFoldDB; A5F419; -.
DR   STRING; 345073.VC395_0240; -.
DR   EnsemblBacteria; ABQ21510; ABQ21510; VC0395_A2587.
DR   GeneID; 57738945; -.
DR   GeneID; 66941187; -.
DR   KEGG; vco:VC0395_A2587; -.
DR   KEGG; vcr:VC395_0240; -.
DR   PATRIC; fig|345073.21.peg.227; -.
DR   eggNOG; COG2862; Bacteria.
DR   HOGENOM; CLU_097887_1_1_6; -.
DR   OMA; HTIMWQV; -.
DR   Proteomes; UP000000249; Chromosome 2.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   HAMAP; MF_00143; UPF0114; 1.
DR   InterPro; IPR005134; UPF0114.
DR   InterPro; IPR020761; UPF0114_bac.
DR   PANTHER; PTHR38596; PTHR38596; 1.
DR   Pfam; PF03350; UPF0114; 1.
DR   TIGRFAMs; TIGR00645; HI0507; 1.
PE   3: Inferred from homology;
KW   Cell membrane; Membrane; Transmembrane; Transmembrane helix.
FT   CHAIN           1..162
FT                   /note="UPF0114 protein VC0395_A2587/VC395_0240"
FT                   /id="PRO_1000071464"
FT   TRANSMEM        15..35
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00143"
FT   TRANSMEM        53..73
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00143"
FT   TRANSMEM        109..126
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00143"
FT   TRANSMEM        136..156
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00143"
SQ   SEQUENCE   162 AA;  18345 MW;  A1CD3A2F4914C043 CRC64;
     MERLIEKLLY SSRWIMAPIY LGLSLLLLAL GIKFFQEIFH LLPNIFTIKE VDLILVALSL
     IDVSLVGGLI VMVMFSGYEN FVSKLDVDES EDKLGWLGKL DTSSLKNKVS ASIVAISSIH
     LLKVFMNTEN IESDKIKWYL LLHITFVVSA FAMGYLDKIT KK