ID   Y378_LACAC              Reviewed;         111 AA.
AC   Q5FM05;
DT   28-JUL-2009, integrated into UniProtKB/Swiss-Prot.
DT   01-MAR-2005, sequence version 1.
DT   03-AUG-2022, entry version 82.
DE   RecName: Full=Nucleoid-associated protein LBA0378 {ECO:0000255|HAMAP-Rule:MF_00274};
GN   OrderedLocusNames=LBA0378;
OS   Lactobacillus acidophilus (strain ATCC 700396 / NCK56 / N2 / NCFM).
OC   Bacteria; Firmicutes; Bacilli; Lactobacillales; Lactobacillaceae;
OC   Lactobacillus.
OX   NCBI_TaxID=272621;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 700396 / NCK56 / N2 / NCFM;
RX   PubMed=15671160; DOI=10.1073/pnas.0409188102;
RA   Altermann E., Russell W.M., Azcarate-Peril M.A., Barrangou R., Buck B.L.,
RA   McAuliffe O., Souther N., Dobson A., Duong T., Callanan M., Lick S.,
RA   Hamrick A., Cano R., Klaenhammer T.R.;
RT   "Complete genome sequence of the probiotic lactic acid bacterium
RT   Lactobacillus acidophilus NCFM.";
RL   Proc. Natl. Acad. Sci. U.S.A. 102:3906-3912(2005).
CC   -!- FUNCTION: Binds to DNA and alters its conformation. May be involved in
CC       regulation of gene expression, nucleoid organization and DNA
CC       protection. {ECO:0000255|HAMAP-Rule:MF_00274}.
CC   -!- SUBUNIT: Homodimer. {ECO:0000255|HAMAP-Rule:MF_00274}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm, nucleoid {ECO:0000255|HAMAP-
CC       Rule:MF_00274}.
CC   -!- SIMILARITY: Belongs to the YbaB/EbfC family. {ECO:0000255|HAMAP-
CC       Rule:MF_00274}.
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DR   EMBL; CP000033; AAV42269.1; -; Genomic_DNA.
DR   RefSeq; WP_003549112.1; NC_006814.3.
DR   RefSeq; YP_193300.1; NC_006814.3.
DR   AlphaFoldDB; Q5FM05; -.
DR   SMR; Q5FM05; -.
DR   STRING; 272621.LBA0378; -.
DR   PRIDE; Q5FM05; -.
DR   EnsemblBacteria; AAV42269; AAV42269; LBA0378.
DR   GeneID; 56941985; -.
DR   KEGG; lac:LBA0378; -.
DR   PATRIC; fig|272621.13.peg.364; -.
DR   eggNOG; COG0718; Bacteria.
DR   HOGENOM; CLU_140930_1_1_9; -.
DR   OMA; MGNMMKQ; -.
DR   BioCyc; LACI272621:G1G49-372-MON; -.
DR   Proteomes; UP000006381; Chromosome.
DR   GO; GO:0043590; C:bacterial nucleoid; IEA:UniProtKB-UniRule.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-UniRule.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR   Gene3D; 3.30.1310.10; -; 1.
DR   HAMAP; MF_00274; DNA_YbaB_EbfC; 1.
DR   InterPro; IPR036894; YbaB-like_sf.
DR   InterPro; IPR004401; YbaB/EbfC.
DR   PANTHER; PTHR33449; PTHR33449; 1.
DR   Pfam; PF02575; YbaB_DNA_bd; 1.
DR   PIRSF; PIRSF004555; UCP004555; 1.
DR   SUPFAM; SSF82607; SSF82607; 1.
DR   TIGRFAMs; TIGR00103; DNA_YbaB_EbfC; 1.
PE   3: Inferred from homology;
KW   Cytoplasm; DNA-binding; Reference proteome.
FT   CHAIN           1..111
FT                   /note="Nucleoid-associated protein LBA0378"
FT                   /id="PRO_1000197658"
SQ   SEQUENCE   111 AA;  12229 MW;  3120E33660804804 CRC64;
     MSRRPNFGGM GMGGMNMQQM MKQAKKLQAQ MAEEQENITA QEFVGKSADD LVVATFSGDR
     KLKDIKIDKD TIDPDDPDML QDLIIDAVNK GLSQIDEATQ ASLGKYTKGL M