ID   Y378_NANEQ              Reviewed;         215 AA.
AC   Q74N11;
DT   24-MAR-2009, integrated into UniProtKB/Swiss-Prot.
DT   05-JUL-2004, sequence version 1.
DT   03-AUG-2022, entry version 79.
DE   RecName: Full=UPF0173 metal-dependent hydrolase NEQ378 {ECO:0000255|HAMAP-Rule:MF_00457};
GN   OrderedLocusNames=NEQ378;
OS   Nanoarchaeum equitans (strain Kin4-M).
OC   Archaea; Nanoarchaeota; Candidatus Nanoarchaeia; Nanoarchaeales;
OC   Nanoarchaeaceae; Nanoarchaeum.
OX   NCBI_TaxID=228908;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Kin4-M;
RX   PubMed=14566062; DOI=10.1073/pnas.1735403100;
RA   Waters E., Hohn M.J., Ahel I., Graham D.E., Adams M.D., Barnstead M.,
RA   Beeson K.Y., Bibbs L., Bolanos R., Keller M., Kretz K., Lin X., Mathur E.,
RA   Ni J., Podar M., Richardson T., Sutton G.G., Simon M., Soell D.,
RA   Stetter K.O., Short J.M., Noorderwier M.;
RT   "The genome of Nanoarchaeum equitans: insights into early archaeal
RT   evolution and derived parasitism.";
RL   Proc. Natl. Acad. Sci. U.S.A. 100:12984-12988(2003).
CC   -!- SIMILARITY: Belongs to the UPF0173 family. {ECO:0000255|HAMAP-
CC       Rule:MF_00457}.
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DR   EMBL; AE017199; AAR39226.1; -; Genomic_DNA.
DR   AlphaFoldDB; Q74N11; -.
DR   SMR; Q74N11; -.
DR   EnsemblBacteria; AAR39226; AAR39226; NEQ378.
DR   KEGG; neq:NEQ378; -.
DR   HOGENOM; CLU_070010_4_0_2; -.
DR   OMA; WHGHSTW; -.
DR   BioCyc; NEQU228908:GJB6-406-MON; -.
DR   Proteomes; UP000000578; Chromosome.
DR   GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-UniRule.
DR   Gene3D; 3.60.15.10; -; 1.
DR   HAMAP; MF_00457; UPF0173; 1.
DR   InterPro; IPR001279; Metallo-B-lactamas.
DR   InterPro; IPR036866; RibonucZ/Hydroxyglut_hydro.
DR   InterPro; IPR022877; UPF0173.
DR   SMART; SM00849; Lactamase_B; 1.
DR   SUPFAM; SSF56281; SSF56281; 1.
PE   3: Inferred from homology;
KW   Hydrolase; Reference proteome.
FT   CHAIN           1..215
FT                   /note="UPF0173 metal-dependent hydrolase NEQ378"
FT                   /id="PRO_0000367236"
SQ   SEQUENCE   215 AA;  24179 MW;  6DAF8081897237B0 CRC64;
     MKIKYMGHSA FIIEHKNRLI IDPYIETIPE VDYVLVTHAH NDHFGNTIEI AKKNNAKVIS
     IYEIAEFVKQ FNIESIGMNF GGTIDIGEKV SLVPAVHSST LYYNGKAYPL GNPGGFVIKG
     NKTIYHAGDT MVFKDMELIG ELFKIDVALL PIGGVFTMDI DQALKAIDLL KPKIVIPMHY
     NTWPIIKADP YEFKRKAEEK GVEAIVLNKD EEIDL