Y3797_VIBC3
ID Y3797_VIBC3 Reviewed; 224 AA.
AC A5F402; C3M395;
DT 26-FEB-2008, integrated into UniProtKB/Swiss-Prot.
DT 12-JUN-2007, sequence version 1.
DT 03-AUG-2022, entry version 77.
DE RecName: Full=UPF0758 protein VC0395_A2597/VC395_0249;
GN OrderedLocusNames=VC0395_A2597, VC395_0249;
OS Vibrio cholerae serotype O1 (strain ATCC 39541 / Classical Ogawa 395 /
OS O395).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Vibrionales; Vibrionaceae;
OC Vibrio.
OX NCBI_TaxID=345073;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 39541 / Classical Ogawa 395 / O395;
RA Heidelberg J.;
RL Submitted (MAR-2007) to the EMBL/GenBank/DDBJ databases.
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 39541 / Classical Ogawa 395 / O395;
RX PubMed=19115014; DOI=10.1371/journal.pone.0004053;
RA Feng L., Reeves P.R., Lan R., Ren Y., Gao C., Zhou Z., Ren Y., Cheng J.,
RA Wang W., Wang J., Qian W., Li D., Wang L.;
RT "A recalibrated molecular clock and independent origins for the cholera
RT pandemic clones.";
RL PLoS ONE 3:E4053-E4053(2008).
CC -!- SIMILARITY: Belongs to the UPF0758 family. {ECO:0000305}.
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DR EMBL; CP000627; ABQ20823.1; -; Genomic_DNA.
DR EMBL; CP001235; ACP08274.1; -; Genomic_DNA.
DR RefSeq; WP_000053959.1; NZ_JAACZH010000028.1.
DR AlphaFoldDB; A5F402; -.
DR SMR; A5F402; -.
DR STRING; 345073.VC395_0249; -.
DR EnsemblBacteria; ABQ20823; ABQ20823; VC0395_A2597.
DR GeneID; 57738954; -.
DR KEGG; vco:VC0395_A2597; -.
DR KEGG; vcr:VC395_0249; -.
DR PATRIC; fig|345073.21.peg.237; -.
DR eggNOG; COG2003; Bacteria.
DR HOGENOM; CLU_073529_0_2_6; -.
DR OMA; HEEFWII; -.
DR Proteomes; UP000000249; Chromosome 2.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0008237; F:metallopeptidase activity; IEA:UniProtKB-KW.
DR GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR CDD; cd08071; MPN_DUF2466; 1.
DR InterPro; IPR037518; MPN.
DR InterPro; IPR025657; RadC_JAB.
DR InterPro; IPR010994; RuvA_2-like.
DR InterPro; IPR001405; UPF0758.
DR InterPro; IPR020891; UPF0758_CS.
DR PANTHER; PTHR30471; PTHR30471; 1.
DR Pfam; PF04002; RadC; 1.
DR SUPFAM; SSF47781; SSF47781; 1.
DR TIGRFAMs; TIGR00608; radc; 1.
DR PROSITE; PS50249; MPN; 1.
DR PROSITE; PS01302; UPF0758; 1.
PE 3: Inferred from homology;
KW Hydrolase; Metal-binding; Metalloprotease; Protease; Zinc.
FT CHAIN 1..224
FT /note="UPF0758 protein VC0395_A2597/VC395_0249"
FT /id="PRO_1000070984"
FT DOMAIN 102..224
FT /note="MPN"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01182"
FT REGION 1..20
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT MOTIF 173..186
FT /note="JAMM motif"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01182"
FT BINDING 173
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /ligand_note="catalytic"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01182"
FT BINDING 175
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /ligand_note="catalytic"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01182"
FT BINDING 186
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /ligand_note="catalytic"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01182"
SQ SEQUENCE 224 AA; 25246 MW; 3A212E369E9CCA6F CRC64;
MSLKQLPTES MPREKLLQRG PQSLSDAELL AIFLRTGTQG MNVLALADLL LRDFGSLRAL
FCASKEQFCR HKGLGEAKFV QLQAVLEMTQ RYLAETLKRG DALTSPQQTK LYLSSVLRDR
QREAFYILFL DNQHRVIRDE ILFEGTIDAA SVYPREVVKR ALHHNAAAVI LAHNHPSGVA
EPSQADRRIT DRLRDALGLV EIRVLDHFVV GDGEVVSFAE RGWI
