Y3804_ARATH
ID Y3804_ARATH Reviewed; 1016 AA.
AC Q9LRT1;
DT 24-NOV-2009, integrated into UniProtKB/Swiss-Prot.
DT 01-OCT-2000, sequence version 1.
DT 03-AUG-2022, entry version 136.
DE RecName: Full=Probably inactive leucine-rich repeat receptor-like protein kinase At3g28040;
DE Flags: Precursor;
GN OrderedLocusNames=At3g28040; ORFNames=MMG15.21;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=10907853; DOI=10.1093/dnares/7.3.217;
RA Kaneko T., Katoh T., Sato S., Nakamura Y., Asamizu E., Tabata S.;
RT "Structural analysis of Arabidopsis thaliana chromosome 3. II. Sequence
RT features of the 4,251,695 bp regions covered by 90 P1, TAC and BAC
RT clones.";
RL DNA Res. 7:217-221(2000).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=20064227; DOI=10.1186/1471-2164-11-19;
RA Gou X., He K., Yang H., Yuan T., Lin H., Clouse S.D., Li J.;
RT "Genome-wide cloning and sequence analysis of leucine-rich repeat receptor-
RT like protein kinase genes in Arabidopsis thaliana.";
RL BMC Genomics 11:19-19(2010).
CC -!- INTERACTION:
CC Q9LRT1; C0LGI2: At1g67720; NbExp=2; IntAct=EBI-16956175, EBI-17070892;
CC Q9LRT1; Q9M9C5: At1g68400; NbExp=3; IntAct=EBI-16956175, EBI-1238661;
CC Q9LRT1; C0LGJ9: At2g02780; NbExp=2; IntAct=EBI-16956175, EBI-20651541;
CC Q9LRT1; C0LGL4: At2g28960; NbExp=2; IntAct=EBI-16956175, EBI-16946048;
CC Q9LRT1; C0LGM1: LRR-RLK; NbExp=2; IntAct=EBI-16956175, EBI-20653589;
CC Q9LRT1; O64483: SIRK; NbExp=2; IntAct=EBI-16956175, EBI-16905038;
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Single-pass type I
CC membrane protein {ECO:0000305}.
CC -!- DOMAIN: The protein kinase domain is predicted to be catalytically
CC inactive. Lacks the conserved Asp active site at position 854, which is
CC replaced by an Asn residue.
CC -!- SIMILARITY: Belongs to the protein kinase superfamily. Ser/Thr protein
CC kinase family. {ECO:0000255|PROSITE-ProRule:PRU00159}.
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DR EMBL; AB028616; BAB01126.1; -; Genomic_DNA.
DR EMBL; CP002686; AEE77394.1; -; Genomic_DNA.
DR EMBL; FJ708729; ACN59324.1; -; mRNA.
DR RefSeq; NP_189443.2; NM_113722.3.
DR AlphaFoldDB; Q9LRT1; -.
DR SMR; Q9LRT1; -.
DR BioGRID; 7758; 46.
DR IntAct; Q9LRT1; 43.
DR STRING; 3702.AT3G28040.1; -.
DR iPTMnet; Q9LRT1; -.
DR PaxDb; Q9LRT1; -.
DR PRIDE; Q9LRT1; -.
DR ProteomicsDB; 242993; -.
DR EnsemblPlants; AT3G28040.1; AT3G28040.1; AT3G28040.
DR GeneID; 822428; -.
DR Gramene; AT3G28040.1; AT3G28040.1; AT3G28040.
DR KEGG; ath:AT3G28040; -.
DR Araport; AT3G28040; -.
DR TAIR; locus:2091353; AT3G28040.
DR eggNOG; ENOG502QU7G; Eukaryota.
DR HOGENOM; CLU_000288_22_1_1; -.
DR InParanoid; Q9LRT1; -.
DR OMA; PNEYPHG; -.
DR OrthoDB; 826997at2759; -.
DR PhylomeDB; Q9LRT1; -.
DR PRO; PR:Q9LRT1; -.
DR Proteomes; UP000006548; Chromosome 3.
DR ExpressionAtlas; Q9LRT1; baseline and differential.
DR Genevisible; Q9LRT1; AT.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005886; C:plasma membrane; IBA:GO_Central.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0004672; F:protein kinase activity; IEA:InterPro.
DR GO; GO:0006468; P:protein phosphorylation; IEA:InterPro.
DR Gene3D; 3.80.10.10; -; 4.
DR InterPro; IPR011009; Kinase-like_dom_sf.
DR InterPro; IPR001611; Leu-rich_rpt.
DR InterPro; IPR003591; Leu-rich_rpt_typical-subtyp.
DR InterPro; IPR032675; LRR_dom_sf.
DR InterPro; IPR013210; LRR_N_plant-typ.
DR InterPro; IPR000719; Prot_kinase_dom.
DR InterPro; IPR017441; Protein_kinase_ATP_BS.
DR Pfam; PF13516; LRR_6; 1.
DR Pfam; PF13855; LRR_8; 3.
DR Pfam; PF08263; LRRNT_2; 1.
DR Pfam; PF00069; Pkinase; 1.
DR SMART; SM00369; LRR_TYP; 11.
DR SUPFAM; SSF56112; SSF56112; 1.
DR PROSITE; PS51450; LRR; 16.
DR PROSITE; PS00107; PROTEIN_KINASE_ATP; 1.
DR PROSITE; PS50011; PROTEIN_KINASE_DOM; 1.
PE 1: Evidence at protein level;
KW ATP-binding; Glycoprotein; Leucine-rich repeat; Membrane;
KW Nucleotide-binding; Phosphoprotein; Receptor; Reference proteome; Repeat;
KW Signal; Transmembrane; Transmembrane helix.
FT SIGNAL 1..26
FT /evidence="ECO:0000255"
FT CHAIN 27..1016
FT /note="Probably inactive leucine-rich repeat receptor-like
FT protein kinase At3g28040"
FT /id="PRO_0000389466"
FT TOPO_DOM 27..646
FT /note="Extracellular"
FT /evidence="ECO:0000255"
FT TRANSMEM 647..667
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 668..1016
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT REPEAT 102..124
FT /note="LRR 1"
FT REPEAT 125..147
FT /note="LRR 2"
FT REPEAT 149..171
FT /note="LRR 3"
FT REPEAT 174..196
FT /note="LRR 4"
FT REPEAT 198..219
FT /note="LRR 5"
FT REPEAT 224..245
FT /note="LRR 6"
FT REPEAT 248..270
FT /note="LRR 7"
FT REPEAT 272..295
FT /note="LRR 8"
FT REPEAT 296..318
FT /note="LRR 9"
FT REPEAT 320..342
FT /note="LRR 10"
FT REPEAT 344..366
FT /note="LRR 11"
FT REPEAT 368..390
FT /note="LRR 12"
FT REPEAT 391..413
FT /note="LRR 13"
FT REPEAT 416..438
FT /note="LRR 14"
FT REPEAT 440..462
FT /note="LRR 15"
FT REPEAT 464..486
FT /note="LRR 16"
FT REPEAT 488..510
FT /note="LRR 17"
FT REPEAT 512..535
FT /note="LRR 18"
FT REPEAT 536..559
FT /note="LRR 19"
FT REPEAT 560..582
FT /note="LRR 20"
FT DOMAIN 726..1013
FT /note="Protein kinase"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00159"
FT BINDING 732..740
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00159"
FT BINDING 755
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00159"
FT MOD_RES 841
FT /note="Phosphotyrosine"
FT /evidence="ECO:0000250|UniProtKB:C0LGT6"
FT MOD_RES 898
FT /note="Phosphotyrosine"
FT /evidence="ECO:0000250|UniProtKB:C0LGT6"
FT CARBOHYD 112
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 135
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 171
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 203
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 349
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 445
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 464
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 509
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 522
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 565
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
SQ SEQUENCE 1016 AA; 111932 MW; 84577A7A2777F1C4 CRC64;
MGKQRRTMIS FTLFLTLTMM SSLINGDTDS IQLNDDVLGL IVFKSDLNDP FSHLESWTED
DNTPCSWSYV KCNPKTSRVI ELSLDGLALT GKINRGIQKL QRLKVLSLSN NNFTGNINAL
SNNNHLQKLD LSHNNLSGQI PSSLGSITSL QHLDLTGNSF SGTLSDDLFN NCSSLRYLSL
SHNHLEGQIP STLFRCSVLN SLNLSRNRFS GNPSFVSGIW RLERLRALDL SSNSLSGSIP
LGILSLHNLK ELQLQRNQFS GALPSDIGLC PHLNRVDLSS NHFSGELPRT LQKLKSLNHF
DVSNNLLSGD FPPWIGDMTG LVHLDFSSNE LTGKLPSSIS NLRSLKDLNL SENKLSGEVP
ESLESCKELM IVQLKGNDFS GNIPDGFFDL GLQEMDFSGN GLTGSIPRGS SRLFESLIRL
DLSHNSLTGS IPGEVGLFIH MRYLNLSWNH FNTRVPPEIE FLQNLTVLDL RNSALIGSVP
ADICESQSLQ ILQLDGNSLT GSIPEGIGNC SSLKLLSLSH NNLTGPIPKS LSNLQELKIL
KLEANKLSGE IPKELGDLQN LLLVNVSFNR LIGRLPLGDV FQSLDQSAIQ GNLGICSPLL
RGPCTLNVPK PLVINPNSYG NGNNMPGNRA SGGSGTFHRR MFLSVSVIVA ISAAILIFSG
VIIITLLNAS VRRRLAFVDN ALESIFSGSS KSGRSLMMGK LVLLNSRTSR SSSSSQEFER
NPESLLNKAS RIGEGVFGTV YKAPLGEQGR NLAVKKLVPS PILQNLEDFD REVRILAKAK
HPNLVSIKGY FWTPDLHLLV SEYIPNGNLQ SKLHEREPST PPLSWDVRYK IILGTAKGLA
YLHHTFRPTT IHFNLKPTNI LLDEKNNPKI SDFGLSRLLT TQDGNTMNNN RFQNALGYVA
PELECQNLRV NEKCDVYGFG VLILELVTGR RPVEYGEDSF VILSDHVRVM LEQGNVLECI
DPVMEEQYSE DEVLPVLKLA LVCTSQIPSN RPTMAEIVQI LQVINSPVPH RIMDSF
