ID   Y3816_MYCA1             Reviewed;         284 AA.
AC   A0QJ99;
DT   28-JUL-2009, integrated into UniProtKB/Swiss-Prot.
DT   28-JUL-2009, sequence version 2.
DT   03-AUG-2022, entry version 69.
DE   RecName: Full=Uncharacterized oxidoreductase MAV_3816;
DE            EC=1.-.-.-;
GN   OrderedLocusNames=MAV_3816;
OS   Mycobacterium avium (strain 104).
OC   Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC   Mycobacterium; Mycobacterium avium complex (MAC).
OX   NCBI_TaxID=243243;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=104;
RA   Fleischmann R.D., Dodson R.J., Haft D.H., Merkel J.S., Nelson W.C.,
RA   Fraser C.M.;
RL   Submitted (OCT-2006) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the aldo/keto reductase family. {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=ABK65524.1; Type=Erroneous initiation; Evidence={ECO:0000305};
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; CP000479; ABK65524.1; ALT_INIT; Genomic_DNA.
DR   AlphaFoldDB; A0QJ99; -.
DR   SMR; A0QJ99; -.
DR   EnsemblBacteria; ABK65524; ABK65524; MAV_3816.
DR   KEGG; mav:MAV_3816; -.
DR   HOGENOM; CLU_023205_0_1_11; -.
DR   Proteomes; UP000001574; Chromosome.
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR   Gene3D; 3.20.20.100; -; 1.
DR   InterPro; IPR020471; AKR.
DR   InterPro; IPR018170; Aldo/ket_reductase_CS.
DR   InterPro; IPR023210; NADP_OxRdtase_dom.
DR   InterPro; IPR036812; NADP_OxRdtase_dom_sf.
DR   PANTHER; PTHR43827; PTHR43827; 1.
DR   Pfam; PF00248; Aldo_ket_red; 1.
DR   PIRSF; PIRSF000097; AKR; 1.
DR   PRINTS; PR00069; ALDKETRDTASE.
DR   SUPFAM; SSF51430; SSF51430; 1.
DR   PROSITE; PS00062; ALDOKETO_REDUCTASE_2; 1.
PE   3: Inferred from homology;
KW   Oxidoreductase.
FT   CHAIN           1..284
FT                   /note="Uncharacterized oxidoreductase MAV_3816"
FT                   /id="PRO_0000380730"
FT   ACT_SITE        59
FT                   /note="Proton donor"
FT                   /evidence="ECO:0000250"
FT   BINDING         117
FT                   /ligand="substrate"
FT                   /evidence="ECO:0000250"
FT   BINDING         197..249
FT                   /ligand="NADP(+)"
FT                   /ligand_id="ChEBI:CHEBI:58349"
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   284 AA;  30340 MW;  5C60715C4FDC1D6F CRC64;
     MNELTGESGS AAPSIALNDE NTMPVLGLGV AELSDDETER AVSAALEVGC RLIDTAAAYG
     NEAAVGRAIA ASGIPRAELF VTTKLATSDQ GFKGAMDACE ASLERLGLDY VDLYLIHWPA
     PALGTYVNSF GGMIQSRGNG HARSIGVSNF TEEYLTTVID LTFVTPAVNQ IELHPLLNQE
     ALRKTNAEHN VVTQSYTPLA LGKLNDHPTV NSVAAEYGKT ASQVLLRWNL QLGNAVIFRS
     ANAEHIASDF DVFDFELAAE HMDAINALND GTRLRPDPDT YEGS