ID   Y3835_MYCTO             Reviewed;         449 AA.
AC   P9WKW4; L0TDX7; P96243; Q7D4S2;
DT   16-APR-2014, integrated into UniProtKB/Swiss-Prot.
DT   16-APR-2014, sequence version 1.
DT   25-MAY-2022, entry version 31.
DE   RecName: Full=Uncharacterized membrane protein MT3943;
GN   OrderedLocusNames=MT3943;
OS   Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh).
OC   Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC   Mycobacterium; Mycobacterium tuberculosis complex.
OX   NCBI_TaxID=83331;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CDC 1551 / Oshkosh;
RX   PubMed=12218036; DOI=10.1128/jb.184.19.5479-5490.2002;
RA   Fleischmann R.D., Alland D., Eisen J.A., Carpenter L., White O.,
RA   Peterson J.D., DeBoy R.T., Dodson R.J., Gwinn M.L., Haft D.H., Hickey E.K.,
RA   Kolonay J.F., Nelson W.C., Umayam L.A., Ermolaeva M.D., Salzberg S.L.,
RA   Delcher A., Utterback T.R., Weidman J.F., Khouri H.M., Gill J., Mikula A.,
RA   Bishai W., Jacobs W.R. Jr., Venter J.C., Fraser C.M.;
RT   "Whole-genome comparison of Mycobacterium tuberculosis clinical and
RT   laboratory strains.";
RL   J. Bacteriol. 184:5479-5490(2002).
CC   -!- FUNCTION: May play a role in septum formation. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Single-pass membrane
CC       protein {ECO:0000305}. Secreted {ECO:0000250}.
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DR   EMBL; AE000516; AAK48310.1; -; Genomic_DNA.
DR   PIR; H70652; H70652.
DR   RefSeq; WP_003420892.1; NZ_KK341227.1.
DR   AlphaFoldDB; P9WKW4; -.
DR   EnsemblBacteria; AAK48310; AAK48310; MT3943.
DR   KEGG; mtc:MT3943; -.
DR   PATRIC; fig|83331.31.peg.4241; -.
DR   HOGENOM; CLU_037731_2_0_11; -.
DR   Proteomes; UP000001020; Chromosome.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   InterPro; IPR026004; Septum_form.
DR   Pfam; PF13845; Septum_form; 1.
PE   3: Inferred from homology;
KW   Cell membrane; Membrane; Secreted; Transmembrane; Transmembrane helix.
FT   CHAIN           1..449
FT                   /note="Uncharacterized membrane protein MT3943"
FT                   /id="PRO_0000427583"
FT   TRANSMEM        45..65
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   REGION          1..33
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          349..449
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        11..26
FT                   /note="Pro residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        349..385
FT                   /note="Pro residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        416..449
FT                   /note="Pro residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   449 AA;  47043 MW;  FD4DB3F778DC41AB CRC64;
     MLDAPEQDPV DPGDPASPPH GEAEQPLPGP RWPRALRASA TRRALLLTAL GGLLIAGLVT
     AIPAVGRAPE RLAGYIASNP VPSTGAKINA SFNRVASGDC LMWPDGTPES AAIVSCADEH
     RFEVAESIDM RTFPGMEYGQ NAAPPSPARI QQISEEQCEA AVRRYLGTKF DPNSKFTISM
     LWPGDRAWRQ AGERRMLCGL QSPGPNNQQL AFKGKVADID QSKVWPAGTC LGIDATTNQP
     IDVPVDCAAP HAMEVSGTVN LAERFPDALP SEPEQDGFIK DACTRMTDAY LAPLKLRTTT
     LTLIYPTLTL PSWSAGSRVV ACSIGATLGN GGWATLVNSA KGALLINGQP PVPPPDIPEE
     RLNLPPIPLQ LPTPRPAPPA QQLPSTPPGT QHLPAQQPVV TPTRPPESHA PASAAPAETQ
     PPPPDAGAPP ATQSPEATPP GPAEPAPAG