ID   Y383_RICTY              Reviewed;         333 AA.
AC   Q68WY2;
DT   06-MAR-2007, integrated into UniProtKB/Swiss-Prot.
DT   11-OCT-2004, sequence version 1.
DT   25-MAY-2022, entry version 71.
DE   RecName: Full=Putative peptidyl-prolyl cis-trans isomerase RT0383;
DE            Short=PPIase RT0383;
DE            EC=5.2.1.8;
DE   AltName: Full=Rotamase RT0383;
GN   OrderedLocusNames=RT0383;
OS   Rickettsia typhi (strain ATCC VR-144 / Wilmington).
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Rickettsiales;
OC   Rickettsiaceae; Rickettsieae; Rickettsia; typhus group.
OX   NCBI_TaxID=257363;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC VR-144 / Wilmington;
RX   PubMed=15317790; DOI=10.1128/jb.186.17.5842-5855.2004;
RA   McLeod M.P., Qin X., Karpathy S.E., Gioia J., Highlander S.K., Fox G.E.,
RA   McNeill T.Z., Jiang H., Muzny D., Jacob L.S., Hawes A.C., Sodergren E.,
RA   Gill R., Hume J., Morgan M., Fan G., Amin A.G., Gibbs R.A., Hong C.,
RA   Yu X.-J., Walker D.H., Weinstock G.M.;
RT   "Complete genome sequence of Rickettsia typhi and comparison with sequences
RT   of other Rickettsiae.";
RL   J. Bacteriol. 186:5842-5855(2004).
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=[protein]-peptidylproline (omega=180) = [protein]-
CC         peptidylproline (omega=0); Xref=Rhea:RHEA:16237, Rhea:RHEA-
CC         COMP:10747, Rhea:RHEA-COMP:10748, ChEBI:CHEBI:83833,
CC         ChEBI:CHEBI:83834; EC=5.2.1.8;
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DR   EMBL; AE017197; AAU03860.1; -; Genomic_DNA.
DR   RefSeq; WP_011190844.1; NC_006142.1.
DR   AlphaFoldDB; Q68WY2; -.
DR   SMR; Q68WY2; -.
DR   STRING; 257363.RT0383; -.
DR   EnsemblBacteria; AAU03860; AAU03860; RT0383.
DR   KEGG; rty:RT0383; -.
DR   eggNOG; COG0545; Bacteria.
DR   HOGENOM; CLU_839076_0_0_5; -.
DR   OMA; TISYRIT; -.
DR   OrthoDB; 568222at2; -.
DR   Proteomes; UP000000604; Chromosome.
DR   GO; GO:0003755; F:peptidyl-prolyl cis-trans isomerase activity; IEA:UniProtKB-KW.
DR   Gene3D; 3.10.50.40; -; 1.
DR   InterPro; IPR046357; PPIase_dom_sf.
DR   InterPro; IPR001179; PPIase_FKBP_dom.
DR   Pfam; PF00254; FKBP_C; 1.
DR   PROSITE; PS50059; FKBP_PPIASE; 1.
PE   4: Predicted;
KW   Isomerase; Rotamase.
FT   CHAIN           1..333
FT                   /note="Putative peptidyl-prolyl cis-trans isomerase RT0383"
FT                   /id="PRO_0000279683"
FT   DOMAIN          129..227
FT                   /note="PPIase FKBP-type"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00277"
SQ   SEQUENCE   333 AA;  37058 MW;  DAECDF4FFFBE1BC8 CRC64;
     MQKFLSLIIV ILILYNIVKL KIYPEDNNNS TTIEQITSNN SSTNAHQASI NNEPTISLNG
     NLFERTVSKI VINALKTEEG KVFFENILQP LNGPINPNDY TIEVHKDLVK TLFKINTFGS
     GNIGPASCGH VVTVFYQISD MNNNLISEDT KTFTLGSAPV MLGLDNVIIG MMVGESREAI
     IPAKYTVNNS NNTIFDDAYN YKVTVILKSI LPQNFVKSNK VKIYDDEIAY RVPLLCGEKV
     SFNAKITRLS NGKILFDSKS TGQPIDMKIG DITYPLIFSY ALQGKVQVGT RSVIAESKTF
     KALGSNLNKV IPHESLPIHE YLLLELNDFK QIK