ID   Y3849_MYCBP             Reviewed;         308 AA.
AC   A1KQC1;
DT   20-JAN-2009, integrated into UniProtKB/Swiss-Prot.
DT   06-FEB-2007, sequence version 1.
DT   03-AUG-2022, entry version 72.
DE   RecName: Full=Putative S-adenosyl-L-methionine-dependent methyltransferase BCG_3849c;
DE            EC=2.1.1.-;
GN   OrderedLocusNames=BCG_3849c;
OS   Mycobacterium bovis (strain BCG / Pasteur 1173P2).
OC   Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC   Mycobacterium; Mycobacterium tuberculosis complex.
OX   NCBI_TaxID=410289;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=BCG / Pasteur 1173P2;
RX   PubMed=17372194; DOI=10.1073/pnas.0700869104;
RA   Brosch R., Gordon S.V., Garnier T., Eiglmeier K., Frigui W., Valenti P.,
RA   Dos Santos S., Duthoy S., Lacroix C., Garcia-Pelayo C., Inwald J.K.,
RA   Golby P., Garcia J.N., Hewinson R.G., Behr M.A., Quail M.A., Churcher C.,
RA   Barrell B.G., Parkhill J., Cole S.T.;
RT   "Genome plasticity of BCG and impact on vaccine efficacy.";
RL   Proc. Natl. Acad. Sci. U.S.A. 104:5596-5601(2007).
CC   -!- FUNCTION: Exhibits S-adenosyl-L-methionine-dependent methyltransferase
CC       activity. {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the UPF0677 family. {ECO:0000305}.
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DR   EMBL; AM408590; CAL73839.1; -; Genomic_DNA.
DR   RefSeq; WP_003420620.1; NC_008769.1.
DR   AlphaFoldDB; A1KQC1; -.
DR   SMR; A1KQC1; -.
DR   KEGG; mbb:BCG_3849c; -.
DR   HOGENOM; CLU_056160_2_1_11; -.
DR   OMA; RMAMETF; -.
DR   Proteomes; UP000001472; Chromosome.
DR   GO; GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
DR   GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR   Gene3D; 3.40.50.150; -; 1.
DR   InterPro; IPR011610; CHP00027_methylltransferase.
DR   InterPro; IPR007213; Ppm1/Ppm2/Tcmp.
DR   InterPro; IPR029063; SAM-dependent_MTases_sf.
DR   Pfam; PF04072; LCM; 1.
DR   SUPFAM; SSF53335; SSF53335; 1.
DR   TIGRFAMs; TIGR00027; mthyl_TIGR00027; 1.
PE   3: Inferred from homology;
KW   Methyltransferase; S-adenosyl-L-methionine; Transferase.
FT   CHAIN           1..308
FT                   /note="Putative S-adenosyl-L-methionine-dependent
FT                   methyltransferase BCG_3849c"
FT                   /id="PRO_0000361148"
FT   BINDING         131
FT                   /ligand="S-adenosyl-L-methionine"
FT                   /ligand_id="ChEBI:CHEBI:59789"
FT                   /evidence="ECO:0000250"
FT   BINDING         160..161
FT                   /ligand="S-adenosyl-L-methionine"
FT                   /ligand_id="ChEBI:CHEBI:59789"
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   308 AA;  33390 MW;  5865CF059D44E304 CRC64;
     MARTDDDSWD LATGVGATAT LVAAGRARAA RAAQPLIDDP FAEPLVRAVG VEFLTRWATG
     ELDAADVDDP DAAWGLQRMT TELVVRTRYF DQFFLDAAAA GVRQAVILAS GLDARGYRLP
     WPADTTVFEV DQPRVLEFKA QTLAGLGAQP TADLRMVPAD LRHDWPDALR RGGFDAAEPA
     AWIAEGLFGY LPPDAQNRLL DHVTDLSAPG SRLALEAFLG SADRDSARVE EMIRTATRGW
     REHGFHLDIW ALNYAGPRHE VSGYLDNHGW RSVGTTTAQL LAAHDLPAAP ALPAGLADRP
     NYWTCVLG