ID   Y3860_BRUME             Reviewed;         319 AA.
AC   Q8YBN9;
DT   08-APR-2008, integrated into UniProtKB/Swiss-Prot.
DT   08-APR-2008, sequence version 2.
DT   03-AUG-2022, entry version 94.
DE   RecName: Full=Putative peptide permease protein BMEII0860;
GN   OrderedLocusNames=BMEII0860;
OS   Brucella melitensis biotype 1 (strain 16M / ATCC 23456 / NCTC 10094).
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Hyphomicrobiales;
OC   Brucellaceae; Brucella/Ochrobactrum group; Brucella.
OX   NCBI_TaxID=224914;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=16M / ATCC 23456 / NCTC 10094;
RX   PubMed=11756688; DOI=10.1073/pnas.221575398;
RA   DelVecchio V.G., Kapatral V., Redkar R.J., Patra G., Mujer C., Los T.,
RA   Ivanova N., Anderson I., Bhattacharyya A., Lykidis A., Reznik G.,
RA   Jablonski L., Larsen N., D'Souza M., Bernal A., Mazur M., Goltsman E.,
RA   Selkov E., Elzer P.H., Hagius S., O'Callaghan D., Letesson J.-J.,
RA   Haselkorn R., Kyrpides N.C., Overbeek R.;
RT   "The genome sequence of the facultative intracellular pathogen Brucella
RT   melitensis.";
RL   Proc. Natl. Acad. Sci. U.S.A. 99:443-448(2002).
CC   -!- FUNCTION: Probably part of an ABC transporter complex that could be
CC       involved in peptide import. Probably responsible for the translocation
CC       of the substrate across the membrane (By similarity). {ECO:0000250}.
CC   -!- SUBUNIT: The complex is composed of two ATP-binding proteins (BMEII0863
CC       and BMEII0864), two transmembrane proteins (BMEII0860 and BMEII0861)
CC       and a solute-binding protein (BMEII0859). {ECO:0000305}.
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000305}; Multi-pass
CC       membrane protein {ECO:0000255|PROSITE-ProRule:PRU00441}.
CC   -!- SIMILARITY: Belongs to the binding-protein-dependent transport system
CC       permease family. {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=AAL54102.1; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR   EMBL; AE008918; AAL54102.1; ALT_INIT; Genomic_DNA.
DR   PIR; AC3617; AC3617.
DR   RefSeq; WP_004681739.1; NZ_GG703779.1.
DR   AlphaFoldDB; Q8YBN9; -.
DR   SMR; Q8YBN9; -.
DR   STRING; 224914.BMEII0860; -.
DR   EnsemblBacteria; AAL54102; AAL54102; BMEII0860.
DR   GeneID; 45125758; -.
DR   KEGG; bme:BMEII0860; -.
DR   PATRIC; fig|224914.52.peg.2502; -.
DR   eggNOG; COG0601; Bacteria.
DR   Proteomes; UP000000419; Chromosome II.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0015833; P:peptide transport; IEA:UniProtKB-KW.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   GO; GO:0055085; P:transmembrane transport; IEA:InterPro.
DR   CDD; cd06261; TM_PBP2; 1.
DR   Gene3D; 1.10.3720.10; -; 1.
DR   InterPro; IPR045621; BPD_transp_1_N.
DR   InterPro; IPR000515; MetI-like.
DR   InterPro; IPR035906; MetI-like_sf.
DR   Pfam; PF00528; BPD_transp_1; 1.
DR   Pfam; PF19300; BPD_transp_1_N; 1.
DR   SUPFAM; SSF161098; SSF161098; 1.
DR   PROSITE; PS50928; ABC_TM1; 1.
PE   3: Inferred from homology;
KW   Cell inner membrane; Cell membrane; Membrane; Peptide transport;
KW   Protein transport; Transmembrane; Transmembrane helix; Transport.
FT   CHAIN           1..319
FT                   /note="Putative peptide permease protein BMEII0860"
FT                   /id="PRO_0000328710"
FT   TRANSMEM        9..29
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT   TRANSMEM        102..122
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT   TRANSMEM        138..158
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT   TRANSMEM        182..202
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT   TRANSMEM        242..262
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT   TRANSMEM        284..304
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT   DOMAIN          98..305
FT                   /note="ABC transmembrane type-1"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
SQ   SEQUENCE   319 AA;  34426 MW;  D1AF00139E480FA4 CRC64;
     MLRYCLHRLL IGLGMLLALT ILIFVLLQLT PGDPIDAYIN PNVAMTQAEM DALRAQLGLD
     RPLPVQYLAW LGQAVQGNLG HSLQRFNETV SGLIASRIGP TLLLMAAGLA IAIVIGVTTG
     IISAVRRNSF PDYSFSVLAL LGISSPAFLT ALLGLYVFSV RLKWAPSGGM LTPATDFSIP
     DLLRHLALPA LVLSIGHAAL IMRYMRSSML ETLNQDYVRT ARAKGVREFW VVVKHTLRNA
     MLPVVTLIGS TIGLAVGGAI FIESVFNWPG MGLLLINAVE TRDYPVIMGA TLVIGACVII
     VNILTDLAYA VIDPRIKVT