ID   Y3861_BRUME             Reviewed;         302 AA.
AC   Q8YBN8;
DT   08-APR-2008, integrated into UniProtKB/Swiss-Prot.
DT   01-MAR-2002, sequence version 1.
DT   25-MAY-2022, entry version 99.
DE   RecName: Full=Putative peptide permease protein BMEII0861;
GN   OrderedLocusNames=BMEII0861;
OS   Brucella melitensis biotype 1 (strain 16M / ATCC 23456 / NCTC 10094).
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Hyphomicrobiales;
OC   Brucellaceae; Brucella/Ochrobactrum group; Brucella.
OX   NCBI_TaxID=224914;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=16M / ATCC 23456 / NCTC 10094;
RX   PubMed=11756688; DOI=10.1073/pnas.221575398;
RA   DelVecchio V.G., Kapatral V., Redkar R.J., Patra G., Mujer C., Los T.,
RA   Ivanova N., Anderson I., Bhattacharyya A., Lykidis A., Reznik G.,
RA   Jablonski L., Larsen N., D'Souza M., Bernal A., Mazur M., Goltsman E.,
RA   Selkov E., Elzer P.H., Hagius S., O'Callaghan D., Letesson J.-J.,
RA   Haselkorn R., Kyrpides N.C., Overbeek R.;
RT   "The genome sequence of the facultative intracellular pathogen Brucella
RT   melitensis.";
RL   Proc. Natl. Acad. Sci. U.S.A. 99:443-448(2002).
CC   -!- FUNCTION: Probably part of an ABC transporter complex that could be
CC       involved in peptide import. Probably responsible for the translocation
CC       of the substrate across the membrane (By similarity). {ECO:0000250}.
CC   -!- SUBUNIT: The complex is composed of two ATP-binding proteins (BMEII0863
CC       and BMEII0864), two transmembrane proteins (BMEII0860 and BMEII0861)
CC       and a solute-binding protein (BMEII0859). {ECO:0000305}.
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000305}; Multi-pass
CC       membrane protein {ECO:0000255|PROSITE-ProRule:PRU00441}.
CC   -!- SIMILARITY: Belongs to the binding-protein-dependent transport system
CC       permease family. {ECO:0000305}.
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DR   EMBL; AE008918; AAL54103.1; -; Genomic_DNA.
DR   PIR; AD3617; AD3617.
DR   AlphaFoldDB; Q8YBN8; -.
DR   SMR; Q8YBN8; -.
DR   STRING; 224914.BMEII0861; -.
DR   EnsemblBacteria; AAL54103; AAL54103; BMEII0861.
DR   KEGG; bme:BMEII0861; -.
DR   eggNOG; COG1173; Bacteria.
DR   OMA; QDPTTYH; -.
DR   Proteomes; UP000000419; Chromosome II.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0015833; P:peptide transport; IEA:UniProtKB-KW.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   GO; GO:0055085; P:transmembrane transport; IEA:InterPro.
DR   CDD; cd06261; TM_PBP2; 1.
DR   Gene3D; 1.10.3720.10; -; 1.
DR   InterPro; IPR000515; MetI-like.
DR   InterPro; IPR035906; MetI-like_sf.
DR   Pfam; PF00528; BPD_transp_1; 1.
DR   SUPFAM; SSF161098; SSF161098; 1.
DR   PROSITE; PS50928; ABC_TM1; 1.
PE   3: Inferred from homology;
KW   Cell inner membrane; Cell membrane; Membrane; Peptide transport;
KW   Protein transport; Transmembrane; Transmembrane helix; Transport.
FT   CHAIN           1..302
FT                   /note="Putative peptide permease protein BMEII0861"
FT                   /id="PRO_0000328711"
FT   TRANSMEM        38..58
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT   TRANSMEM        101..121
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT   TRANSMEM        147..167
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT   TRANSMEM        230..250
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT   TRANSMEM        268..288
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT   DOMAIN          97..288
FT                   /note="ABC transmembrane type-1"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT   REGION          1..22
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   302 AA;  32568 MW;  9215403A0DCC8CAB CRC64;
     MRSSIHASRL RKMGQSIPAS TGPMARSANR FLQNRAAIFG LVLLTPLLFA VLTYPLWLPY
     KPNDIDLMAM NSAPSWKHWF GTDGVGRDVF ARTMEGGRIS LLVAVSSVVL STAIGFLIGA
     ISALGGRWAD AIAMRSVDLA MTLPPVIFLL VLASIIGSGI WSTVVVIALL SWPVLSRMIR
     ARLLELRERE FVMASRGMGA GLGHLLFRHG LPNSIDILVV YATLQVANAI LLEAGLSFLG
     LGVPPPAASW SNMLNAARST AVLEQFPWQW LFPGGALVLA VLAINFIGDG LRDAFDPRAE
     LN