Y390_MYCGE
ID Y390_MYCGE Reviewed; 660 AA.
AC Q49430; Q49332; Q49356;
DT 01-NOV-1997, integrated into UniProtKB/Swiss-Prot.
DT 01-NOV-1996, sequence version 1.
DT 03-AUG-2022, entry version 130.
DE RecName: Full=Putative ABC transporter ATP-binding MG390;
GN OrderedLocusNames=MG390;
OS Mycoplasma genitalium (strain ATCC 33530 / DSM 19775 / NCTC 10195 / G37)
OS (Mycoplasmoides genitalium).
OC Bacteria; Tenericutes; Mollicutes; Mycoplasmataceae; Mycoplasma.
OX NCBI_TaxID=243273;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 33530 / DSM 19775 / NCTC 10195 / G37;
RX PubMed=7569993; DOI=10.1126/science.270.5235.397;
RA Fraser C.M., Gocayne J.D., White O., Adams M.D., Clayton R.A.,
RA Fleischmann R.D., Bult C.J., Kerlavage A.R., Sutton G.G., Kelley J.M.,
RA Fritchman J.L., Weidman J.F., Small K.V., Sandusky M., Fuhrmann J.L.,
RA Nguyen D.T., Utterback T.R., Saudek D.M., Phillips C.A., Merrick J.M.,
RA Tomb J.-F., Dougherty B.A., Bott K.F., Hu P.-C., Lucier T.S.,
RA Peterson S.N., Smith H.O., Hutchison C.A. III, Venter J.C.;
RT "The minimal gene complement of Mycoplasma genitalium.";
RL Science 270:397-403(1995).
RN [2]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 392-581.
RC STRAIN=ATCC 33530 / DSM 19775 / NCTC 10195 / G37;
RX PubMed=8253680; DOI=10.1128/jb.175.24.7918-7930.1993;
RA Peterson S.N., Hu P.-C., Bott K.F., Hutchison C.A. III;
RT "A survey of the Mycoplasma genitalium genome by using random sequencing.";
RL J. Bacteriol. 175:7918-7930(1993).
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC protein {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the ABC transporter superfamily. {ECO:0000305}.
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DR EMBL; L43967; AAC71618.1; -; Genomic_DNA.
DR EMBL; U02248; AAA03404.1; -; Genomic_DNA.
DR EMBL; U02218; AAA03372.1; -; Genomic_DNA.
DR PIR; B64243; B64243.
DR RefSeq; WP_010869463.1; NC_000908.2.
DR AlphaFoldDB; Q49430; -.
DR SMR; Q49430; -.
DR STRING; 243273.MG_390; -.
DR EnsemblBacteria; AAC71618; AAC71618; MG_390.
DR KEGG; mge:MG_390; -.
DR eggNOG; COG2274; Bacteria.
DR HOGENOM; CLU_488191_0_0_14; -.
DR OMA; YNDCSIA; -.
DR OrthoDB; 643917at2; -.
DR BioCyc; MGEN243273:G1GJ2-486-MON; -.
DR Proteomes; UP000000807; Chromosome.
DR GO; GO:0005887; C:integral component of plasma membrane; IBA:GO_Central.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0042626; F:ATPase-coupled transmembrane transporter activity; IBA:GO_Central.
DR GO; GO:0008234; F:cysteine-type peptidase activity; IEA:UniProtKB-KW.
DR GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR Gene3D; 3.40.50.300; -; 1.
DR InterPro; IPR036640; ABC1_TM_sf.
DR InterPro; IPR003439; ABC_transporter-like_ATP-bd.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR005074; Peptidase_C39.
DR Pfam; PF00005; ABC_tran; 1.
DR Pfam; PF03412; Peptidase_C39; 1.
DR SUPFAM; SSF52540; SSF52540; 1.
DR SUPFAM; SSF90123; SSF90123; 1.
DR PROSITE; PS50990; PEPTIDASE_C39; 1.
PE 3: Inferred from homology;
KW ATP-binding; Cell membrane; Hydrolase; Membrane; Nucleotide-binding;
KW Protease; Reference proteome; Thiol protease; Transmembrane;
KW Transmembrane helix; Transport.
FT CHAIN 1..660
FT /note="Putative ABC transporter ATP-binding MG390"
FT /id="PRO_0000093247"
FT TRANSMEM 150..170
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 188..208
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 265..285
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 290..310
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 379..399
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 402..422
FT /note="Helical"
FT /evidence="ECO:0000255"
FT DOMAIN 6..126
FT /note="Peptidase C39"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00362"
FT DOMAIN 464..657
FT /note="ABC transporter"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00362"
FT ACT_SITE 12
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00362"
FT BINDING 494..501
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00362"
FT CONFLICT 392
FT /note="L -> F (in Ref. 2; AAA03404)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 660 AA; 76380 MW; 3CB9AEF9FFB89771 CRC64;
MKIIYQEQQN ECGICVIGML ANAIHDEKYV HDELLEQINL PPNGLSLFEM ESYGKKFGLE
INSYQLTFQE LKELDSKFII VHFKDHFVIV KNKHENSWEV YDPAKGKYLL TDEKLEKLWT
GYAATVAKAF KEIPPVNKSN FFSNFFDFNL VTFYVFIELI IIGISTLLAT ASRTIITNTV
DFGTAVNLVV LVVYFSCLKG LNLLLQVILQ LIRNFLFWKQ YRGYLGWIIQ SLQQKSFVYF
SNKSPNQLIE RQFYLKEVLS FFNFYIPNLI ISCVVALIIG VLIGINQLEF LLIAIAQIVV
NAGLFCYDFF FTKKITKKEI PYVELQNKIS LQLDENLREE QNKKRFNFLM LNFRKALLQN
QNINNQKEIN RLTIENIKSF FQQGFDFAIL GLGVIGIIEQ RYQLSFLFYV FGIQSLFSTY
ATRIVQFGAA INIYHYCREK LVNLFIETKK DEGIKVNWQC PDEISLENLS VTLNQHVDLA
NLSLKIKNET VIFGQNGSGK STFLKILTGR GFEYTGNIKF NNVDLKRCSK EQLFENVYYL
KGQNLMQTEA NDFGFSEALF NNQNPHIYQL LFDAGVQNQT KLSSGQKQIL QLFLLSNIKN
KVILLDECMN AIAPEIKNRV YQLLVKPLTL NNFVVLVEHD LSFASEAQNK INLTNYLRNS
