ID   Y3913_DICDI             Reviewed;         667 AA.
AC   Q54QE8;
DT   10-FEB-2009, integrated into UniProtKB/Swiss-Prot.
DT   24-MAY-2005, sequence version 1.
DT   25-MAY-2022, entry version 55.
DE   RecName: Full=Heat shock protein DDB_G0283913;
GN   ORFNames=DDB_G0283913;
OS   Dictyostelium discoideum (Slime mold).
OC   Eukaryota; Amoebozoa; Evosea; Eumycetozoa; Dictyostelia; Dictyosteliales;
OC   Dictyosteliaceae; Dictyostelium.
OX   NCBI_TaxID=44689;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=AX4;
RX   PubMed=15875012; DOI=10.1038/nature03481;
RA   Eichinger L., Pachebat J.A., Gloeckner G., Rajandream M.A., Sucgang R.,
RA   Berriman M., Song J., Olsen R., Szafranski K., Xu Q., Tunggal B.,
RA   Kummerfeld S., Madera M., Konfortov B.A., Rivero F., Bankier A.T.,
RA   Lehmann R., Hamlin N., Davies R., Gaudet P., Fey P., Pilcher K., Chen G.,
RA   Saunders D., Sodergren E.J., Davis P., Kerhornou A., Nie X., Hall N.,
RA   Anjard C., Hemphill L., Bason N., Farbrother P., Desany B., Just E.,
RA   Morio T., Rost R., Churcher C.M., Cooper J., Haydock S., van Driessche N.,
RA   Cronin A., Goodhead I., Muzny D.M., Mourier T., Pain A., Lu M., Harper D.,
RA   Lindsay R., Hauser H., James K.D., Quiles M., Madan Babu M., Saito T.,
RA   Buchrieser C., Wardroper A., Felder M., Thangavelu M., Johnson D.,
RA   Knights A., Loulseged H., Mungall K.L., Oliver K., Price C., Quail M.A.,
RA   Urushihara H., Hernandez J., Rabbinowitsch E., Steffen D., Sanders M.,
RA   Ma J., Kohara Y., Sharp S., Simmonds M.N., Spiegler S., Tivey A.,
RA   Sugano S., White B., Walker D., Woodward J.R., Winckler T., Tanaka Y.,
RA   Shaulsky G., Schleicher M., Weinstock G.M., Rosenthal A., Cox E.C.,
RA   Chisholm R.L., Gibbs R.A., Loomis W.F., Platzer M., Kay R.R.,
RA   Williams J.G., Dear P.H., Noegel A.A., Barrell B.G., Kuspa A.;
RT   "The genome of the social amoeba Dictyostelium discoideum.";
RL   Nature 435:43-57(2005).
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the small heat shock protein (HSP20) family.
CC       {ECO:0000255|PROSITE-ProRule:PRU00285}.
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DR   EMBL; AAFI02000058; EAL65444.1; -; Genomic_DNA.
DR   RefSeq; XP_638796.1; XM_633704.1.
DR   AlphaFoldDB; Q54QE8; -.
DR   PaxDb; Q54QE8; -.
DR   EnsemblProtists; EAL65444; EAL65444; DDB_G0283913.
DR   GeneID; 8624320; -.
DR   KEGG; ddi:DDB_G0283913; -.
DR   dictyBase; DDB_G0283913; -.
DR   HOGENOM; CLU_421179_0_0_1; -.
DR   InParanoid; Q54QE8; -.
DR   PhylomeDB; Q54QE8; -.
DR   PRO; PR:Q54QE8; -.
DR   Proteomes; UP000002195; Chromosome 4.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   InterPro; IPR002068; A-crystallin/Hsp20_dom.
DR   PROSITE; PS01031; SHSP; 1.
PE   3: Inferred from homology;
KW   Coiled coil; Membrane; Reference proteome; Stress response; Transmembrane;
KW   Transmembrane helix.
FT   CHAIN           1..667
FT                   /note="Heat shock protein DDB_G0283913"
FT                   /id="PRO_0000363911"
FT   TRANSMEM        2..22
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        224..244
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   DOMAIN          551..667
FT                   /note="sHSP"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00285"
FT   REGION          432..478
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          18..82
FT                   /evidence="ECO:0000255"
FT   COMPBIAS        441..461
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        462..478
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   667 AA;  76560 MW;  A4B5B861271A9A86 CRC64;
     MFVGTLVIII CTTLIIIIKK ILKRKKEKLN LKESKKKKQD NERKNFEGLL TKKRVEVGDL
     KKEIEKLNKD KIELAKKLNC YIGDSSIPAN GIREYDIIID IPSVDYLSQS RKSWIIYVSN
     QLKQKMGSSN YNKKRPLHSL LKEYKKFSTL ACLGVLNKGK TFFINKYNGT YLPSGTQAQT
     IGLSLSISSL NETITIDTAG SNTALQVCED KTEEHLARKE STEMFICDMS FSLASIIVYV
     LNELTWNDQR FILALQSKIQ SLRSESNIIK KLLVVHNYPK VNSQEELLSE IKTYIESPFN
     GNFHHHHVDI KKIESKEEIV LFFVESVNKT HHFFLCNDNS EFGKRYNQLT IEKIRTYKNY
     NDNLDLDKVL LTSLQNNMIP YCKSPKKLKI TEHEPTINQI NNNNSSNNKS QLEERPIADS
     LFQTQSFLHP SIDDTIQDND KSGSEVSTPT ISSSSSSPLQ PIIKDEKDDN IENKSDEANT
     SLKYKPLFTS FGTDEYSKHL KELCKLHQMV SPHRSSIKQI PAFTISPEID CNRENDFKLI
     ANRIEIIGLN MVFSSGFKPF HDIVKVNSDL RYIIEVPQLE MEDIEFETKH LGSQWYLNIK
     GIKKLRYDSN DQTTVYPSNL TSLCPSQNQR RDGLFEFSLP IPTEYLPIKP AVSLDKGVIT
     FKFEKIG