ID   Y3936_METAC             Reviewed;         155 AA.
AC   Q8TJ52;
DT   10-OCT-2002, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-2002, sequence version 1.
DT   25-MAY-2022, entry version 95.
DE   RecName: Full=UPF0060 membrane protein MA_3936;
GN   OrderedLocusNames=MA_3936;
OS   Methanosarcina acetivorans (strain ATCC 35395 / DSM 2834 / JCM 12185 /
OS   C2A).
OC   Archaea; Euryarchaeota; Stenosarchaea group; Methanomicrobia;
OC   Methanosarcinales; Methanosarcinaceae; Methanosarcina.
OX   NCBI_TaxID=188937;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 35395 / DSM 2834 / JCM 12185 / C2A;
RX   PubMed=11932238; DOI=10.1101/gr.223902;
RA   Galagan J.E., Nusbaum C., Roy A., Endrizzi M.G., Macdonald P., FitzHugh W.,
RA   Calvo S., Engels R., Smirnov S., Atnoor D., Brown A., Allen N., Naylor J.,
RA   Stange-Thomann N., DeArellano K., Johnson R., Linton L., McEwan P.,
RA   McKernan K., Talamas J., Tirrell A., Ye W., Zimmer A., Barber R.D.,
RA   Cann I., Graham D.E., Grahame D.A., Guss A.M., Hedderich R.,
RA   Ingram-Smith C., Kuettner H.C., Krzycki J.A., Leigh J.A., Li W., Liu J.,
RA   Mukhopadhyay B., Reeve J.N., Smith K., Springer T.A., Umayam L.A.,
RA   White O., White R.H., de Macario E.C., Ferry J.G., Jarrell K.F., Jing H.,
RA   Macario A.J.L., Paulsen I.T., Pritchett M., Sowers K.R., Swanson R.V.,
RA   Zinder S.H., Lander E., Metcalf W.W., Birren B.;
RT   "The genome of Methanosarcina acetivorans reveals extensive metabolic and
RT   physiological diversity.";
RL   Genome Res. 12:532-542(2002).
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000250}; Multi-pass membrane
CC       protein {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the UPF0060 family. {ECO:0000305}.
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DR   EMBL; AE010299; AAM07287.1; -; Genomic_DNA.
DR   AlphaFoldDB; Q8TJ52; -.
DR   TCDB; 2.A.7.26.2; the drug/metabolite transporter (dmt) superfamily.
DR   EnsemblBacteria; AAM07287; AAM07287; MA_3936.
DR   KEGG; mac:MA_3936; -.
DR   HOGENOM; CLU_1691530_0_0_2; -.
DR   InParanoid; Q8TJ52; -.
DR   PhylomeDB; Q8TJ52; -.
DR   Proteomes; UP000002487; Chromosome.
DR   GO; GO:0005887; C:integral component of plasma membrane; IBA:GO_Central.
DR   InterPro; IPR003844; UPF0060.
DR   PANTHER; PTHR36116; PTHR36116; 1.
DR   Pfam; PF02694; UPF0060; 1.
PE   3: Inferred from homology;
KW   Cell membrane; Membrane; Reference proteome; Transmembrane;
KW   Transmembrane helix.
FT   CHAIN           1..155
FT                   /note="UPF0060 membrane protein MA_3936"
FT                   /id="PRO_0000162358"
FT   TRANSMEM        8..28
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        35..55
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        62..82
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   155 AA;  17952 MW;  995E9406817DB335 CRC64;
     MIELGVSLCP FFLAALFEIR GGYLICLWLR NNMRAVFGPL GRLMLAVCGI IPTFQPSHFG
     RVYAAHGGIF IVFSLIWDLF VDKKIPDRYD HRGNNNVCGC FHYVLRLSLI GRYSVISFCN
     FQTPRQRISD FFLSRSIKHN FYLFFCNQTL GNYFV