ID   Y395_MYCGE              Reviewed;         524 AA.
AC   P47635;
DT   01-FEB-1996, integrated into UniProtKB/Swiss-Prot.
DT   01-FEB-1996, sequence version 1.
DT   03-AUG-2022, entry version 115.
DE   RecName: Full=Uncharacterized lipoprotein MG395;
DE   Flags: Precursor;
GN   OrderedLocusNames=MG395;
OS   Mycoplasma genitalium (strain ATCC 33530 / DSM 19775 / NCTC 10195 / G37)
OS   (Mycoplasmoides genitalium).
OC   Bacteria; Tenericutes; Mollicutes; Mycoplasmataceae; Mycoplasma.
OX   NCBI_TaxID=243273;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 33530 / DSM 19775 / NCTC 10195 / G37;
RX   PubMed=7569993; DOI=10.1126/science.270.5235.397;
RA   Fraser C.M., Gocayne J.D., White O., Adams M.D., Clayton R.A.,
RA   Fleischmann R.D., Bult C.J., Kerlavage A.R., Sutton G.G., Kelley J.M.,
RA   Fritchman J.L., Weidman J.F., Small K.V., Sandusky M., Fuhrmann J.L.,
RA   Nguyen D.T., Utterback T.R., Saudek D.M., Phillips C.A., Merrick J.M.,
RA   Tomb J.-F., Dougherty B.A., Bott K.F., Hu P.-C., Lucier T.S.,
RA   Peterson S.N., Smith H.O., Hutchison C.A. III, Venter J.C.;
RT   "The minimal gene complement of Mycoplasma genitalium.";
RL   Science 270:397-403(1995).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 40-152.
RC   STRAIN=ATCC 33530 / DSM 19775 / NCTC 10195 / G37;
RX   PubMed=8253680; DOI=10.1128/jb.175.24.7918-7930.1993;
RA   Peterson S.N., Hu P.-C., Bott K.F., Hutchison C.A. III;
RT   "A survey of the Mycoplasma genitalium genome by using random sequencing.";
RL   J. Bacteriol. 175:7918-7930(1993).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 255-326.
RC   STRAIN=ATCC 33530 / DSM 19775 / NCTC 10195 / G37;
RX   PubMed=1945886; DOI=10.1093/nar/19.21.6027;
RA   Peterson S.N., Schramm N., Hu P.-C., Bott K.F., Hutchison C.A. III;
RT   "A random sequencing approach for placing markers on the physical map of
RT   Mycoplasma genitalium.";
RL   Nucleic Acids Res. 19:6027-6031(1991).
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000255|PROSITE-
CC       ProRule:PRU00303}; Lipid-anchor {ECO:0000255|PROSITE-ProRule:PRU00303}.
CC   -!- SIMILARITY: Belongs to the MG067/MG068/MG395 family. {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; L43967; AAC71623.1; -; Genomic_DNA.
DR   EMBL; U02260; AAD12525.1; -; Genomic_DNA.
DR   EMBL; X61530; CAA43742.1; -; Genomic_DNA.
DR   PIR; G64243; G64243.
DR   RefSeq; WP_010869465.1; NZ_AAGX01000001.1.
DR   AlphaFoldDB; P47635; -.
DR   STRING; 243273.MG_395; -.
DR   EnsemblBacteria; AAC71623; AAC71623; MG_395.
DR   KEGG; mge:MG_395; -.
DR   eggNOG; ENOG5030N1R; Bacteria.
DR   HOGENOM; CLU_038569_1_0_14; -.
DR   OMA; QYGYGLM; -.
DR   OrthoDB; 1230381at2; -.
DR   BioCyc; MGEN243273:G1GJ2-491-MON; -.
DR   Proteomes; UP000000807; Chromosome.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   InterPro; IPR022382; Mycoplasma_peptidase_DUF31.
DR   InterPro; IPR009003; Peptidase_S1_PA.
DR   InterPro; IPR022381; Uncharacterised_MG067.
DR   Pfam; PF01732; DUF31; 1.
DR   PRINTS; PR00840; Y06768FAMILY.
DR   SUPFAM; SSF50494; SSF50494; 1.
DR   PROSITE; PS51257; PROKAR_LIPOPROTEIN; 1.
PE   3: Inferred from homology;
KW   Cell membrane; Lipoprotein; Membrane; Palmitate; Reference proteome;
KW   Signal.
FT   SIGNAL          1..26
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00303"
FT   CHAIN           27..524
FT                   /note="Uncharacterized lipoprotein MG395"
FT                   /id="PRO_0000018737"
FT   REGION          37..68
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        38..68
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   LIPID           27
FT                   /note="N-palmitoyl cysteine"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00303"
FT   LIPID           27
FT                   /note="S-diacylglycerol cysteine"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00303"
SQ   SEQUENCE   524 AA;  60932 MW;  0CB9913D7DD717D6 CRC64;
     MLKIDMWFKL KSLGFSLISL QALLASCSAV SPVPVPIEEK NDSTTDNNAT PFKDEQSDQG
     TEVNQQPKVE QKVYNRNFKF NTSFIPEESD IYRKGYDLTF TLNFTSFSND SYGTGWLIDW
     KGDENTTQKQ GSFFAYIATN LHVADGLRNI GDHWPYSKTD DQREFNEYES TVYFSIGKYT
     NKTDITKLYQ EEKLEQRKVN DSLLSIQTSN IPKTAYTATN FLKGVNSIKP VYADFAVIEL
     ELNLENLRDW QIFNEFIKPA INTYKSLGDS TNIFETKDLE QHWNHSHYLL GYPVLERGYD
     QNRLLEQKEE FARTHNFNQK SQLWSKNTYL VSTAKEIPVI TKNARKDGQI GSEIFSKKTQ
     DSHVDKVIKH EKGIVTFQNF KNFKLKYHDK EYQQYGYGLM LDDTNLPGGS SGSAIFNNNQ
     KINSIYFGVL EVYKNSKTHK DNIGMSQLLR TSKRESEKNK TRTTNNRDKF QHYDLIFGDS
     NTKSFYAQFA KKHNTHLYDQ IKSSEKEEFK YVDKNNQKTP FLLR