ID   Y395_RICPR              Reviewed;         333 AA.
AC   Q9ZDD6;
DT   30-MAY-2000, integrated into UniProtKB/Swiss-Prot.
DT   01-MAY-1999, sequence version 1.
DT   25-MAY-2022, entry version 85.
DE   RecName: Full=Putative peptidyl-prolyl cis-trans isomerase RP395;
DE            Short=PPIase RP395;
DE            EC=5.2.1.8;
DE   AltName: Full=Rotamase RP395;
GN   OrderedLocusNames=RP395;
OS   Rickettsia prowazekii (strain Madrid E).
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Rickettsiales;
OC   Rickettsiaceae; Rickettsieae; Rickettsia; typhus group.
OX   NCBI_TaxID=272947;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Madrid E;
RX   PubMed=9823893; DOI=10.1038/24094;
RA   Andersson S.G.E., Zomorodipour A., Andersson J.O., Sicheritz-Ponten T.,
RA   Alsmark U.C.M., Podowski R.M., Naeslund A.K., Eriksson A.-S., Winkler H.H.,
RA   Kurland C.G.;
RT   "The genome sequence of Rickettsia prowazekii and the origin of
RT   mitochondria.";
RL   Nature 396:133-140(1998).
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=[protein]-peptidylproline (omega=180) = [protein]-
CC         peptidylproline (omega=0); Xref=Rhea:RHEA:16237, Rhea:RHEA-
CC         COMP:10747, Rhea:RHEA-COMP:10748, ChEBI:CHEBI:83833,
CC         ChEBI:CHEBI:83834; EC=5.2.1.8;
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DR   EMBL; AJ235271; CAA14852.1; -; Genomic_DNA.
DR   PIR; B71697; B71697.
DR   RefSeq; NP_220776.1; NC_000963.1.
DR   RefSeq; WP_004597576.1; NC_000963.1.
DR   AlphaFoldDB; Q9ZDD6; -.
DR   SMR; Q9ZDD6; -.
DR   STRING; 272947.RP395; -.
DR   EnsemblBacteria; CAA14852; CAA14852; CAA14852.
DR   GeneID; 57569520; -.
DR   KEGG; rpr:RP395; -.
DR   PATRIC; fig|272947.5.peg.408; -.
DR   eggNOG; COG0545; Bacteria.
DR   HOGENOM; CLU_839076_0_0_5; -.
DR   OMA; TISYRIT; -.
DR   Proteomes; UP000002480; Chromosome.
DR   GO; GO:0003755; F:peptidyl-prolyl cis-trans isomerase activity; IEA:UniProtKB-KW.
DR   Gene3D; 3.10.50.40; -; 1.
DR   InterPro; IPR046357; PPIase_dom_sf.
DR   InterPro; IPR001179; PPIase_FKBP_dom.
DR   Pfam; PF00254; FKBP_C; 1.
DR   PROSITE; PS50059; FKBP_PPIASE; 1.
PE   4: Predicted;
KW   Isomerase; Reference proteome; Rotamase.
FT   CHAIN           1..333
FT                   /note="Putative peptidyl-prolyl cis-trans isomerase RP395"
FT                   /id="PRO_0000075380"
FT   DOMAIN          129..227
FT                   /note="PPIase FKBP-type"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00277"
FT   REGION          29..51
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   333 AA;  37152 MW;  36F723DA438E77DF CRC64;
     MQKFLSLIIV ILILYNIVKL KIYPEDNNNS TTIKQTTSNN SSTNEHQTSI NNEPTISLNG
     NLFERTVSKI VINALKTEEG KIFFENILQP LNGPINPNDY TIEVHKDLVK TLFKINTFGS
     GNIGPASCGH VVTVFYQISD MNNNLISEDT KTFTLGSAPV MLGLDNVIIG MMVGEAREAI
     IPAKYTVNNS NNIIFDDAYN YKVTVILKSI LPQNFVESNK VKIYDDEIAY RVPLLCGEKV
     SFHAKITRLS NGKILFDSKS KGQPLDMKIG DITYPLIFSY ALQGKVQVGT RSVIAEGKTF
     KALGSNLNKI IAHESLPIHE YLLLELNDFK QIK