ID   Y3968_DICDI             Reviewed;         375 AA.
AC   Q54UJ6;
DT   14-OCT-2008, integrated into UniProtKB/Swiss-Prot.
DT   24-MAY-2005, sequence version 1.
DT   25-MAY-2022, entry version 49.
DE   RecName: Full=Uncharacterized transmembrane protein DDB_G0281039;
DE   Flags: Precursor;
GN   ORFNames=DDB_G0281039;
OS   Dictyostelium discoideum (Slime mold).
OC   Eukaryota; Amoebozoa; Evosea; Eumycetozoa; Dictyostelia; Dictyosteliales;
OC   Dictyosteliaceae; Dictyostelium.
OX   NCBI_TaxID=44689;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=AX4;
RX   PubMed=15875012; DOI=10.1038/nature03481;
RA   Eichinger L., Pachebat J.A., Gloeckner G., Rajandream M.A., Sucgang R.,
RA   Berriman M., Song J., Olsen R., Szafranski K., Xu Q., Tunggal B.,
RA   Kummerfeld S., Madera M., Konfortov B.A., Rivero F., Bankier A.T.,
RA   Lehmann R., Hamlin N., Davies R., Gaudet P., Fey P., Pilcher K., Chen G.,
RA   Saunders D., Sodergren E.J., Davis P., Kerhornou A., Nie X., Hall N.,
RA   Anjard C., Hemphill L., Bason N., Farbrother P., Desany B., Just E.,
RA   Morio T., Rost R., Churcher C.M., Cooper J., Haydock S., van Driessche N.,
RA   Cronin A., Goodhead I., Muzny D.M., Mourier T., Pain A., Lu M., Harper D.,
RA   Lindsay R., Hauser H., James K.D., Quiles M., Madan Babu M., Saito T.,
RA   Buchrieser C., Wardroper A., Felder M., Thangavelu M., Johnson D.,
RA   Knights A., Loulseged H., Mungall K.L., Oliver K., Price C., Quail M.A.,
RA   Urushihara H., Hernandez J., Rabbinowitsch E., Steffen D., Sanders M.,
RA   Ma J., Kohara Y., Sharp S., Simmonds M.N., Spiegler S., Tivey A.,
RA   Sugano S., White B., Walker D., Woodward J.R., Winckler T., Tanaka Y.,
RA   Shaulsky G., Schleicher M., Weinstock G.M., Rosenthal A., Cox E.C.,
RA   Chisholm R.L., Gibbs R.A., Loomis W.F., Platzer M., Kay R.R.,
RA   Williams J.G., Dear P.H., Noegel A.A., Barrell B.G., Kuspa A.;
RT   "The genome of the social amoeba Dictyostelium discoideum.";
RL   Nature 435:43-57(2005).
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Single-pass type I
CC       membrane protein {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; AAFI02000040; EAL66816.1; -; Genomic_DNA.
DR   RefSeq; XP_640780.1; XM_635688.1.
DR   AlphaFoldDB; Q54UJ6; -.
DR   STRING; 44689.DDB0203968; -.
DR   PaxDb; Q54UJ6; -.
DR   EnsemblProtists; EAL66816; EAL66816; DDB_G0281039.
DR   GeneID; 8622833; -.
DR   KEGG; ddi:DDB_G0281039; -.
DR   dictyBase; DDB_G0281039; -.
DR   HOGENOM; CLU_738572_0_0_1; -.
DR   PRO; PR:Q54UJ6; -.
DR   Proteomes; UP000002195; Chromosome 3.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
PE   3: Inferred from homology;
KW   Membrane; Reference proteome; Signal; Transmembrane; Transmembrane helix.
FT   SIGNAL          1..20
FT                   /evidence="ECO:0000255"
FT   CHAIN           21..375
FT                   /note="Uncharacterized transmembrane protein DDB_G0281039"
FT                   /id="PRO_0000352398"
FT   TOPO_DOM        21..335
FT                   /note="Extracellular"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        336..356
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        357..375
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   REGION          30..74
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          113..253
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        40..55
FT                   /note="Basic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        56..74
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        164..241
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   375 AA;  43256 MW;  32137D490933B671 CRC64;
     MKNKLFIILI IFIILKIVIC QNTTPSKLIP QQQQKQKQQQ TQPHHHHHHH QQHQQHQQQH
     QPNQQIKQQQ QPQQQQLQQQ QKQLEQQQQQ QKIQQQQQPQ QQLLQQQQHF PNSQNVIKTP
     PHHTQQRVPH HHGPNGAPHH HGPNGAPHHH GPNGAPHYHS PNAAPHSGHN TQGHVQTNHV
     NNINKNNINN NNNNNNNNNN NNNNNNNNNI NDNKNIRNNI PSPATKDPNP FINNKPKVNS
     NTPQPFPHPP HNHNLVNGGR PVIHKQIPPH HHIPMGGGNI QSNQHFQGFQ PSQVFTGSQP
     SSNSASPILF NSENPFYKEE YYKHPEKQVE RKITPIMVLY ILLASTMVIQ LFIMVFKQVK
     HIREINAKTT MESLL