Y4006_DICDI
ID Y4006_DICDI Reviewed; 357 AA.
AC Q54EB4;
DT 02-SEP-2008, integrated into UniProtKB/Swiss-Prot.
DT 24-MAY-2005, sequence version 1.
DT 25-MAY-2022, entry version 48.
DE RecName: Full=Putative uncharacterized transmembrane protein DDB_G0291600;
GN ORFNames=DDB_G0291600;
OS Dictyostelium discoideum (Slime mold).
OC Eukaryota; Amoebozoa; Evosea; Eumycetozoa; Dictyostelia; Dictyosteliales;
OC Dictyosteliaceae; Dictyostelium.
OX NCBI_TaxID=44689;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AX4;
RX PubMed=15875012; DOI=10.1038/nature03481;
RA Eichinger L., Pachebat J.A., Gloeckner G., Rajandream M.A., Sucgang R.,
RA Berriman M., Song J., Olsen R., Szafranski K., Xu Q., Tunggal B.,
RA Kummerfeld S., Madera M., Konfortov B.A., Rivero F., Bankier A.T.,
RA Lehmann R., Hamlin N., Davies R., Gaudet P., Fey P., Pilcher K., Chen G.,
RA Saunders D., Sodergren E.J., Davis P., Kerhornou A., Nie X., Hall N.,
RA Anjard C., Hemphill L., Bason N., Farbrother P., Desany B., Just E.,
RA Morio T., Rost R., Churcher C.M., Cooper J., Haydock S., van Driessche N.,
RA Cronin A., Goodhead I., Muzny D.M., Mourier T., Pain A., Lu M., Harper D.,
RA Lindsay R., Hauser H., James K.D., Quiles M., Madan Babu M., Saito T.,
RA Buchrieser C., Wardroper A., Felder M., Thangavelu M., Johnson D.,
RA Knights A., Loulseged H., Mungall K.L., Oliver K., Price C., Quail M.A.,
RA Urushihara H., Hernandez J., Rabbinowitsch E., Steffen D., Sanders M.,
RA Ma J., Kohara Y., Sharp S., Simmonds M.N., Spiegler S., Tivey A.,
RA Sugano S., White B., Walker D., Woodward J.R., Winckler T., Tanaka Y.,
RA Shaulsky G., Schleicher M., Weinstock G.M., Rosenthal A., Cox E.C.,
RA Chisholm R.L., Gibbs R.A., Loomis W.F., Platzer M., Kay R.R.,
RA Williams J.G., Dear P.H., Noegel A.A., Barrell B.G., Kuspa A.;
RT "The genome of the social amoeba Dictyostelium discoideum.";
RL Nature 435:43-57(2005).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Multi-pass membrane
CC protein {ECO:0000305}.
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DR EMBL; AAFI02000177; EAL61784.1; -; Genomic_DNA.
DR RefSeq; XP_635326.1; XM_630234.1.
DR AlphaFoldDB; Q54EB4; -.
DR PaxDb; Q54EB4; -.
DR EnsemblProtists; EAL61784; EAL61784; DDB_G0291600.
DR GeneID; 8628271; -.
DR KEGG; ddi:DDB_G0291600; -.
DR dictyBase; DDB_G0291600; ldpA.
DR eggNOG; ENOG502RE6J; Eukaryota.
DR HOGENOM; CLU_777129_0_0_1; -.
DR InParanoid; Q54EB4; -.
DR OMA; FFWRAKS; -.
DR PRO; PR:Q54EB4; -.
DR Proteomes; UP000002195; Chromosome 6.
DR GO; GO:0005783; C:endoplasmic reticulum; IDA:dictyBase.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005811; C:lipid droplet; IDA:dictyBase.
PE 4: Predicted;
KW Coiled coil; Membrane; Reference proteome; Transmembrane;
KW Transmembrane helix.
FT CHAIN 1..357
FT /note="Putative uncharacterized transmembrane protein
FT DDB_G0291600"
FT /id="PRO_0000346876"
FT TRANSMEM 21..41
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 86..106
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 135..155
FT /note="Helical"
FT /evidence="ECO:0000255"
FT REGION 184..229
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 283..357
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 305..337
FT /evidence="ECO:0000255"
FT COMPBIAS 191..225
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 283..307
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 308..340
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 357 AA; 41538 MW; DCDB1888A982FBB2 CRC64;
MNTSTTTKSK NKPPKSTPST FIKIIEFWFY LIQILTVLFS WRVYFLFIDS KKKIENNNNN
DNDNNNTNKN DEKRYLTFKE KVQHNFFCLF TDTLYFMMLI ITCTLFFWRL KDTLSLLKKS
DSSKYKQIIW DQFSGGFVEF GSFTVLLLLK WPVIFKVFWN KGTEKEDKST WSQIFMREFS
QEVDKNKLGG PKPPTTNTTN FSGNGSSSST TNATSSSSSQ ANNKRAMSDD EWRHAFRRDL
QNIGFEFDSQ TGDVSKFPPT EVMEQYQKSA EFRDLILASG SLKAGSEQQD KNKNNNNNNN
NNGPKIEEYD NQKQEEEENE EKETNKQQTQ KDDEKETSTT TTSSNKKSKK GKKNKRN