ID   Y402_BUCBP              Reviewed;         281 AA.
AC   Q89AB5;
DT   13-APR-2004, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-2003, sequence version 1.
DT   03-AUG-2022, entry version 101.
DE   RecName: Full=Uncharacterized MscS family protein bbp_402;
GN   OrderedLocusNames=bbp_402;
OS   Buchnera aphidicola subsp. Baizongia pistaciae (strain Bp).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Erwiniaceae; Buchnera.
OX   NCBI_TaxID=224915;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Bp;
RX   PubMed=12522265; DOI=10.1073/pnas.0235981100;
RA   van Ham R.C.H.J., Kamerbeek J., Palacios C., Rausell C., Abascal F.,
RA   Bastolla U., Fernandez J.M., Jimenez L., Postigo M., Silva F.J.,
RA   Tamames J., Viguera E., Latorre A., Valencia A., Moran F., Moya A.;
RT   "Reductive genome evolution in Buchnera aphidicola.";
RL   Proc. Natl. Acad. Sci. U.S.A. 100:581-586(2003).
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the MscS (TC 1.A.23) family. {ECO:0000305}.
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DR   EMBL; AE016826; AAO27114.1; -; Genomic_DNA.
DR   RefSeq; WP_011091515.1; NC_004545.1.
DR   AlphaFoldDB; Q89AB5; -.
DR   SMR; Q89AB5; -.
DR   STRING; 224915.bbp_402; -.
DR   EnsemblBacteria; AAO27114; AAO27114; bbp_402.
DR   GeneID; 56470939; -.
DR   KEGG; bab:bbp_402; -.
DR   eggNOG; COG0668; Bacteria.
DR   HOGENOM; CLU_037945_1_1_6; -.
DR   OMA; GMQDTLT; -.
DR   OrthoDB; 1903165at2; -.
DR   Proteomes; UP000000601; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0008381; F:mechanosensitive ion channel activity; IEA:InterPro.
DR   Gene3D; 2.30.30.60; -; 1.
DR   InterPro; IPR010920; LSM_dom_sf.
DR   InterPro; IPR045275; MscS_archaea/bacteria_type.
DR   InterPro; IPR006685; MscS_channel.
DR   InterPro; IPR011066; MscS_channel_C.
DR   InterPro; IPR006686; MscS_channel_CS.
DR   InterPro; IPR011014; MscS_channel_TM-2.
DR   InterPro; IPR023408; MscS_dom_sf.
DR   InterPro; IPR008910; TM_helix.
DR   PANTHER; PTHR30221; PTHR30221; 1.
DR   Pfam; PF00924; MS_channel; 1.
DR   Pfam; PF05552; TM_helix; 1.
DR   SUPFAM; SSF50182; SSF50182; 1.
DR   SUPFAM; SSF82689; SSF82689; 1.
DR   SUPFAM; SSF82861; SSF82861; 1.
DR   PROSITE; PS01246; UPF0003; 1.
PE   3: Inferred from homology;
KW   Cell membrane; Membrane; Reference proteome; Transmembrane;
KW   Transmembrane helix.
FT   CHAIN           1..281
FT                   /note="Uncharacterized MscS family protein bbp_402"
FT                   /id="PRO_0000110248"
FT   TRANSMEM        23..45
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        65..87
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        94..116
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   281 AA;  31337 MW;  F11BD4807E078C21 CRC64;
     MTQLNVVNDI NHAGNWLIRN QELLLSYIIN LISSIIILII GFFAAKIISN LINKVLITQK
     IDTTIANFLA ALVRYIIITF ALIASLGCIG VQTTSVIAIL GAAGMAIGLA LQGSLSNFAA
     GVLLVILRPF RTGEYVNLEK ISGTVLNIHV FYTTFRTLDG KIVVIPNGKI ISGNIINYSR
     EKARRNEFII GVSYDSDIDK VIKILKNVVK NEKRVLKDRD IIVGLSELAP SSLNFIVRCW
     SHTDDINIVY WDLMVKFKKA LDSNNINIPY PQFDINLKKK Y