ID   CARQ_MYXXA              Reviewed;         174 AA.
AC   Q06909;
DT   01-OCT-1994, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-1994, sequence version 1.
DT   03-AUG-2022, entry version 93.
DE   RecName: Full=RNA polymerase sigma factor CarQ;
GN   Name=carQ;
OS   Myxococcus xanthus.
OC   Bacteria; Proteobacteria; Deltaproteobacteria; Myxococcales;
OC   Cystobacterineae; Myxococcaceae; Myxococcus.
OX   NCBI_TaxID=34;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=DK101;
RX   PubMed=7934835; DOI=10.1111/j.1365-2958.1993.tb00943.x;
RA   McGowan S.J., Gorham H.C., Hodgson D.A.;
RT   "Light-induced carotenogenesis in Myxococcus xanthus: DNA sequence analysis
RT   of the carR region.";
RL   Mol. Microbiol. 10:713-735(1993).
RN   [2]
RP   SIMILARITY TO OTHER ECF SIGMA FACTORS.
RX   PubMed=8052622; DOI=10.1073/pnas.91.16.7573;
RA   Lonetto M.A., Brown K.L., Rudd K.E., Buttner M.J.;
RT   "Analysis of the Streptomyces coelicolor sigE gene reveals the existence of
RT   a subfamily of eubacterial RNA polymerase sigma factors involved in the
RT   regulation of extracytoplasmic functions.";
RL   Proc. Natl. Acad. Sci. U.S.A. 91:7573-7577(1994).
CC   -!- FUNCTION: Sigma factors are initiation factors that promote the
CC       attachment of RNA polymerase to specific initiation sites and are then
CC       released. This sigma factor regulates genes for the light induced
CC       biosynthesis of carotenoids.
CC   -!- INDUCTION: By light.
CC   -!- SIMILARITY: Belongs to the sigma-70 factor family. ECF subfamily.
CC       {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; X71062; CAA50381.1; -; Genomic_DNA.
DR   PIR; S39877; S39877.
DR   AlphaFoldDB; Q06909; -.
DR   SMR; Q06909; -.
DR   OMA; RAHRGYE; -.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0016987; F:sigma factor activity; IEA:UniProtKB-KW.
DR   GO; GO:0016117; P:carotenoid biosynthetic process; IEA:UniProtKB-KW.
DR   GO; GO:0006352; P:DNA-templated transcription, initiation; IEA:InterPro.
DR   GO; GO:0006950; P:response to stress; IEA:UniProt.
DR   Gene3D; 1.10.10.10; -; 1.
DR   InterPro; IPR039425; RNA_pol_sigma-70-like.
DR   InterPro; IPR014284; RNA_pol_sigma-70_dom.
DR   InterPro; IPR000838; RNA_pol_sigma70_ECF_CS.
DR   InterPro; IPR007627; RNA_pol_sigma70_r2.
DR   InterPro; IPR013249; RNA_pol_sigma70_r4_t2.
DR   InterPro; IPR013325; RNA_pol_sigma_r2.
DR   InterPro; IPR013324; RNA_pol_sigma_r3/r4-like.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   PANTHER; PTHR43133; PTHR43133; 1.
DR   Pfam; PF04542; Sigma70_r2; 1.
DR   Pfam; PF08281; Sigma70_r4_2; 1.
DR   SUPFAM; SSF88659; SSF88659; 1.
DR   SUPFAM; SSF88946; SSF88946; 1.
DR   TIGRFAMs; TIGR02937; sigma70-ECF; 1.
DR   PROSITE; PS01063; SIGMA70_ECF; 1.
PE   2: Evidence at transcript level;
KW   Carotenoid biosynthesis; DNA-binding; Sigma factor; Transcription;
KW   Transcription regulation.
FT   CHAIN           1..174
FT                   /note="RNA polymerase sigma factor CarQ"
FT                   /id="PRO_0000094008"
FT   DNA_BIND        136..155
FT                   /note="H-T-H motif"
FT                   /evidence="ECO:0000250"
FT   REGION          86..106
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   MOTIF           39..52
FT                   /note="Polymerase core binding"
SQ   SEQUENCE   174 AA;  19575 MW;  39B4DE383036DFE3 CRC64;
     MERFRDGAQD AFEDLFARHA PRVQGFLARM VRNGALAEDL LQATFLSVIR SRGRYEPGTR
     FIPWLMTIAA NAARDALRHQ RHVDAYASRE DTATPASAAP DDSDPSLRRH LLDALQQLHP
     DHREAVVLSK VEGWSFEEIG ALRGISPGAA RLRAHRGYEK LRELLGELEL EVAR