ID   Y4064_MYCPA             Reviewed;         313 AA.
AC   Q73SK9;
DT   20-JAN-2009, integrated into UniProtKB/Swiss-Prot.
DT   05-JUL-2004, sequence version 1.
DT   03-AUG-2022, entry version 79.
DE   RecName: Full=Putative S-adenosyl-L-methionine-dependent methyltransferase MAP_4064c;
DE            EC=2.1.1.-;
GN   OrderedLocusNames=MAP_4064c;
OS   Mycolicibacterium paratuberculosis (strain ATCC BAA-968 / K-10)
OS   (Mycobacterium paratuberculosis).
OC   Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC   Mycobacterium; Mycobacterium avium complex (MAC).
OX   NCBI_TaxID=262316;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC BAA-968 / K-10;
RX   PubMed=16116077; DOI=10.1073/pnas.0505662102;
RA   Li L., Bannantine J.P., Zhang Q., Amonsin A., May B.J., Alt D., Banerji N.,
RA   Kanjilal S., Kapur V.;
RT   "The complete genome sequence of Mycobacterium avium subspecies
RT   paratuberculosis.";
RL   Proc. Natl. Acad. Sci. U.S.A. 102:12344-12349(2005).
CC   -!- FUNCTION: Exhibits S-adenosyl-L-methionine-dependent methyltransferase
CC       activity. {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the UPF0677 family. {ECO:0000305}.
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DR   EMBL; AE016958; AAS06614.1; -; Genomic_DNA.
DR   RefSeq; WP_010950219.1; NC_002944.2.
DR   AlphaFoldDB; Q73SK9; -.
DR   SMR; Q73SK9; -.
DR   EnsemblBacteria; AAS06614; AAS06614; MAP_4064c.
DR   KEGG; mpa:MAP_4064c; -.
DR   PATRIC; fig|262316.17.peg.4329; -.
DR   eggNOG; COG3315; Bacteria.
DR   HOGENOM; CLU_056160_2_1_11; -.
DR   OMA; PWGLAQM; -.
DR   Proteomes; UP000000580; Chromosome.
DR   GO; GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
DR   GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR   Gene3D; 3.40.50.150; -; 1.
DR   InterPro; IPR011610; CHP00027_methylltransferase.
DR   InterPro; IPR007213; Ppm1/Ppm2/Tcmp.
DR   InterPro; IPR029063; SAM-dependent_MTases_sf.
DR   Pfam; PF04072; LCM; 1.
DR   SUPFAM; SSF53335; SSF53335; 1.
DR   TIGRFAMs; TIGR00027; mthyl_TIGR00027; 1.
PE   3: Inferred from homology;
KW   Methyltransferase; Reference proteome; S-adenosyl-L-methionine;
KW   Transferase.
FT   CHAIN           1..313
FT                   /note="Putative S-adenosyl-L-methionine-dependent
FT                   methyltransferase MAP_4064c"
FT                   /id="PRO_0000361184"
FT   BINDING         129
FT                   /ligand="S-adenosyl-L-methionine"
FT                   /ligand_id="ChEBI:CHEBI:59789"
FT                   /evidence="ECO:0000250"
FT   BINDING         158..159
FT                   /ligand="S-adenosyl-L-methionine"
FT                   /ligand_id="ChEBI:CHEBI:59789"
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   313 AA;  33336 MW;  9C55170EA9234470 CRC64;
     MTVPNDDTWG PATSVGTTAT MAAAARAIAT RDGVINDPFA EPLVRAVGVN FLTRWAIGEL
     VASDVDVEGS PWGLAQMPAS IAARTRYFDE FYADAAAAGI RQAVILASGL DTRAYRLDWP
     AGMTVFEIDQ PAVIEFKTTA LARLGAEPKA DLRTVAVDLR DDWSTALATA GLDSSKPTAW
     IAEGLFGYLA PEAQDGLLDA VTALSTPGSR LGSEAVPNTA DMDPHAARER MRAATAKWRD
     HGFELDVDVI SFAGERHDVG AYLQAHGWTT VATPMAELLA DHGLPAIARA DDDRQTMNGV
     TYYTSTLGTG RQR