Y4083_YERPE
ID Y4083_YERPE Reviewed; 552 AA.
AC Q8Z9V7; Q0W9V1;
DT 15-MAY-2002, integrated into UniProtKB/Swiss-Prot.
DT 01-MAR-2002, sequence version 1.
DT 25-MAY-2022, entry version 128.
DE RecName: Full=Putative transport protein YPO4083/y4100/YP_3992 {ECO:0000255|HAMAP-Rule:MF_01016};
GN OrderedLocusNames=YPO4083, y4100, YP_3992;
OS Yersinia pestis.
OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC Yersiniaceae; Yersinia.
OX NCBI_TaxID=632;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CO-92 / Biovar Orientalis;
RX PubMed=11586360; DOI=10.1038/35097083;
RA Parkhill J., Wren B.W., Thomson N.R., Titball R.W., Holden M.T.G.,
RA Prentice M.B., Sebaihia M., James K.D., Churcher C.M., Mungall K.L.,
RA Baker S., Basham D., Bentley S.D., Brooks K., Cerdeno-Tarraga A.-M.,
RA Chillingworth T., Cronin A., Davies R.M., Davis P., Dougan G., Feltwell T.,
RA Hamlin N., Holroyd S., Jagels K., Karlyshev A.V., Leather S., Moule S.,
RA Oyston P.C.F., Quail M.A., Rutherford K.M., Simmonds M., Skelton J.,
RA Stevens K., Whitehead S., Barrell B.G.;
RT "Genome sequence of Yersinia pestis, the causative agent of plague.";
RL Nature 413:523-527(2001).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=KIM10+ / Biovar Mediaevalis;
RX PubMed=12142430; DOI=10.1128/jb.184.16.4601-4611.2002;
RA Deng W., Burland V., Plunkett G. III, Boutin A., Mayhew G.F., Liss P.,
RA Perna N.T., Rose D.J., Mau B., Zhou S., Schwartz D.C., Fetherston J.D.,
RA Lindler L.E., Brubaker R.R., Plano G.V., Straley S.C., McDonough K.A.,
RA Nilles M.L., Matson J.S., Blattner F.R., Perry R.D.;
RT "Genome sequence of Yersinia pestis KIM.";
RL J. Bacteriol. 184:4601-4611(2002).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=91001 / Biovar Mediaevalis;
RX PubMed=15368893; DOI=10.1093/dnares/11.3.179;
RA Song Y., Tong Z., Wang J., Wang L., Guo Z., Han Y., Zhang J., Pei D.,
RA Zhou D., Qin H., Pang X., Han Y., Zhai J., Li M., Cui B., Qi Z., Jin L.,
RA Dai R., Chen F., Li S., Ye C., Du Z., Lin W., Wang J., Yu J., Yang H.,
RA Wang J., Huang P., Yang R.;
RT "Complete genome sequence of Yersinia pestis strain 91001, an isolate
RT avirulent to humans.";
RL DNA Res. 11:179-197(2004).
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000255|HAMAP-Rule:MF_01016};
CC Multi-pass membrane protein {ECO:0000255|HAMAP-Rule:MF_01016}.
CC -!- SIMILARITY: Belongs to the AAE transporter (TC 2.A.81) family. YidE
CC subfamily. {ECO:0000255|HAMAP-Rule:MF_01016}.
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DR EMBL; AL590842; CAL22653.1; -; Genomic_DNA.
DR EMBL; AE009952; AAM87643.1; -; Genomic_DNA.
DR EMBL; AE017042; AAS64132.1; -; Genomic_DNA.
DR PIR; AB0496; AB0496.
DR RefSeq; WP_002209634.1; NZ_WUCM01000035.1.
DR RefSeq; YP_002348937.1; NC_003143.1.
DR AlphaFoldDB; Q8Z9V7; -.
DR SMR; Q8Z9V7; -.
DR IntAct; Q8Z9V7; 3.
DR STRING; 214092.YPO4083; -.
DR PaxDb; Q8Z9V7; -.
DR DNASU; 1149047; -.
DR EnsemblBacteria; AAM87643; AAM87643; y4100.
DR EnsemblBacteria; AAS64132; AAS64132; YP_3992.
DR GeneID; 57974635; -.
DR KEGG; ype:YPO4083; -.
DR KEGG; ypk:y4100; -.
DR KEGG; ypm:YP_3992; -.
DR PATRIC; fig|214092.21.peg.4624; -.
DR eggNOG; COG0569; Bacteria.
DR eggNOG; COG2985; Bacteria.
DR HOGENOM; CLU_035023_3_1_6; -.
DR OMA; AMWLIRL; -.
DR Proteomes; UP000000815; Chromosome.
DR Proteomes; UP000001019; Chromosome.
DR Proteomes; UP000002490; Chromosome.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0008324; F:cation transmembrane transporter activity; IEA:InterPro.
DR GO; GO:0006813; P:potassium ion transport; IEA:InterPro.
DR Gene3D; 3.30.70.1450; -; 2.
DR HAMAP; MF_01016; YidE; 1.
DR InterPro; IPR006037; RCK_C.
DR InterPro; IPR036721; RCK_C_sf.
DR InterPro; IPR023018; Transpt_YidE_put.
DR InterPro; IPR006512; YidE_YbjL.
DR Pfam; PF06826; Asp-Al_Ex; 2.
DR Pfam; PF02080; TrkA_C; 1.
DR SUPFAM; SSF116726; SSF116726; 2.
DR TIGRFAMs; TIGR01625; YidE_YbjL_dupl; 2.
DR PROSITE; PS51202; RCK_C; 2.
PE 3: Inferred from homology;
KW Cell membrane; Membrane; Reference proteome; Repeat; Transmembrane;
KW Transmembrane helix; Transport.
FT CHAIN 1..552
FT /note="Putative transport protein YPO4083/y4100/YP_3992"
FT /id="PRO_0000208808"
FT TRANSMEM 1..21
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01016"
FT TRANSMEM 26..46
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01016"
FT TRANSMEM 65..85
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01016"
FT TRANSMEM 96..116
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01016"
FT TRANSMEM 119..139
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01016"
FT TRANSMEM 158..178
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01016"
FT TRANSMEM 371..391
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01016"
FT TRANSMEM 393..413
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01016"
FT TRANSMEM 439..459
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01016"
FT TRANSMEM 464..484
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01016"
FT TRANSMEM 493..513
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01016"
FT TRANSMEM 530..550
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01016"
FT DOMAIN 192..276
FT /note="RCK C-terminal 1"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01016"
FT DOMAIN 279..361
FT /note="RCK C-terminal 2"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01016"
SQ SEQUENCE 552 AA; 58702 MW; 9FB23AA927A2F31C CRC64;
MSAIALTVSM LALVAVLGLW IGNWKIYGVG LGIGGVLFGG IIVGHFAQTY QIVLNGDMLH
FIQEFGLILF VYTIGIQVGP GFFSSLRVSG LRLNCFAILM VVVGGLVTAI IHKLFAVPLP
IILGVFSGAV TNTPALGAAQ QILTDLGSPP QLVSQMGMGY AMAYPFGICG ILLVMWLIRL
FFKINIDREA KAFDSSYGQN RELLQTMNVA VRNPNLHGLS VQDVPLLNSD EVVCSRLKRG
DLLMVPMPAT VIEIGDYLHL VGQRDALEKV RLVVGEEVDV TLSTAGTALQ TARVVVTNEA
VLGKKIRDLN LKQKYDVVIT RLNRAGIELV ASNSASLQFG DILNLVGRPE AIEAVSAIVG
NAQQKLQQVQ MLPVFIGVGL GVLLGSIPLF VPGFPAALRL GLAGGPLVVA LILGRIGSIG
KLYWFMPPSA NLALRELGIV LFLSVVGLKS GGDFINTLVN GDGLAWIGYG AMITGIPLLT
VGILARMLVK MNYLTLCGML AGSMTDPPAL AFANGLHPTS GAAALSYATV YPLAMFLRIM
SPQILAVLFW TL