ID   Y4098_METAC             Reviewed;         144 AA.
AC   Q8TIP4;
DT   28-NOV-2003, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-2002, sequence version 1.
DT   03-AUG-2022, entry version 94.
DE   RecName: Full=UPF0292 protein MA_4098 {ECO:0000255|HAMAP-Rule:MF_01095};
GN   OrderedLocusNames=MA_4098;
OS   Methanosarcina acetivorans (strain ATCC 35395 / DSM 2834 / JCM 12185 /
OS   C2A).
OC   Archaea; Euryarchaeota; Stenosarchaea group; Methanomicrobia;
OC   Methanosarcinales; Methanosarcinaceae; Methanosarcina.
OX   NCBI_TaxID=188937;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 35395 / DSM 2834 / JCM 12185 / C2A;
RX   PubMed=11932238; DOI=10.1101/gr.223902;
RA   Galagan J.E., Nusbaum C., Roy A., Endrizzi M.G., Macdonald P., FitzHugh W.,
RA   Calvo S., Engels R., Smirnov S., Atnoor D., Brown A., Allen N., Naylor J.,
RA   Stange-Thomann N., DeArellano K., Johnson R., Linton L., McEwan P.,
RA   McKernan K., Talamas J., Tirrell A., Ye W., Zimmer A., Barber R.D.,
RA   Cann I., Graham D.E., Grahame D.A., Guss A.M., Hedderich R.,
RA   Ingram-Smith C., Kuettner H.C., Krzycki J.A., Leigh J.A., Li W., Liu J.,
RA   Mukhopadhyay B., Reeve J.N., Smith K., Springer T.A., Umayam L.A.,
RA   White O., White R.H., de Macario E.C., Ferry J.G., Jarrell K.F., Jing H.,
RA   Macario A.J.L., Paulsen I.T., Pritchett M., Sowers K.R., Swanson R.V.,
RA   Zinder S.H., Lander E., Metcalf W.W., Birren B.;
RT   "The genome of Methanosarcina acetivorans reveals extensive metabolic and
RT   physiological diversity.";
RL   Genome Res. 12:532-542(2002).
CC   -!- COFACTOR:
CC       Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
CC         Evidence={ECO:0000255|HAMAP-Rule:MF_01095};
CC       Note=Binds two Mg(2+) per subunit. {ECO:0000255|HAMAP-Rule:MF_01095};
CC   -!- SIMILARITY: Belongs to the UPF0292 family. {ECO:0000255|HAMAP-
CC       Rule:MF_01095}.
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DR   EMBL; AE010299; AAM07446.1; -; Genomic_DNA.
DR   RefSeq; WP_011023990.1; NC_003552.1.
DR   AlphaFoldDB; Q8TIP4; -.
DR   SMR; Q8TIP4; -.
DR   STRING; 188937.MA_4098; -.
DR   EnsemblBacteria; AAM07446; AAM07446; MA_4098.
DR   GeneID; 1475992; -.
DR   KEGG; mac:MA_4098; -.
DR   HOGENOM; CLU_140789_0_0_2; -.
DR   InParanoid; Q8TIP4; -.
DR   OMA; VMILTDF; -.
DR   OrthoDB; 99443at2157; -.
DR   PhylomeDB; Q8TIP4; -.
DR   Proteomes; UP000002487; Chromosome.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   CDD; cd01027; TOPRIM_RNase_M5_like; 1.
DR   HAMAP; MF_01095; UPF0292; 1.
DR   InterPro; IPR006171; TOPRIM_domain.
DR   InterPro; IPR034141; TOPRIM_RNase_M5-like.
DR   InterPro; IPR022972; UPF0292.
DR   Pfam; PF13662; Toprim_4; 1.
DR   SMART; SM00493; TOPRIM; 1.
DR   PROSITE; PS50880; TOPRIM; 1.
PE   3: Inferred from homology;
KW   Magnesium; Metal-binding; Reference proteome.
FT   CHAIN           1..144
FT                   /note="UPF0292 protein MA_4098"
FT                   /id="PRO_0000143950"
FT   DOMAIN          28..109
FT                   /note="Toprim"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01095"
FT   BINDING         34
FT                   /ligand="Mg(2+)"
FT                   /ligand_id="ChEBI:CHEBI:18420"
FT                   /ligand_label="1"
FT                   /ligand_note="catalytic"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01095"
FT   BINDING         78
FT                   /ligand="Mg(2+)"
FT                   /ligand_id="ChEBI:CHEBI:18420"
FT                   /ligand_label="1"
FT                   /ligand_note="catalytic"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01095"
FT   BINDING         78
FT                   /ligand="Mg(2+)"
FT                   /ligand_id="ChEBI:CHEBI:18420"
FT                   /ligand_label="2"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01095"
FT   BINDING         80
FT                   /ligand="Mg(2+)"
FT                   /ligand_id="ChEBI:CHEBI:18420"
FT                   /ligand_label="2"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01095"
SQ   SEQUENCE   144 AA;  16789 MW;  98B846C52C8D681C CRC64;
     MTDIEIYRKR LERIEELLLE LSEYSKKGAV IIVEGKRDIL SMKRLGIDGN FELATRHSLF
     NFSERIAKLG CEVIILTDWD RRGDILATKL SEYFGNFGIK PELQIRNKLR LITQKEIKDV
     ESLYTYVSKL RSKTGVSFDQ EDNI