ID   Y4104_STRCO             Reviewed;         218 AA.
AC   Q9RKM3;
DT   01-DEC-2000, integrated into UniProtKB/Swiss-Prot.
DT   01-MAY-2000, sequence version 1.
DT   25-MAY-2022, entry version 104.
DE   RecName: Full=UPF0126 membrane protein SCO4104;
GN   OrderedLocusNames=SCO4104; ORFNames=SCD17.08c;
OS   Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145).
OC   Bacteria; Actinobacteria; Streptomycetales; Streptomycetaceae;
OC   Streptomyces; Streptomyces albidoflavus group.
OX   NCBI_TaxID=100226;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC BAA-471 / A3(2) / M145;
RX   PubMed=12000953; DOI=10.1038/417141a;
RA   Bentley S.D., Chater K.F., Cerdeno-Tarraga A.-M., Challis G.L.,
RA   Thomson N.R., James K.D., Harris D.E., Quail M.A., Kieser H., Harper D.,
RA   Bateman A., Brown S., Chandra G., Chen C.W., Collins M., Cronin A.,
RA   Fraser A., Goble A., Hidalgo J., Hornsby T., Howarth S., Huang C.-H.,
RA   Kieser T., Larke L., Murphy L.D., Oliver K., O'Neil S., Rabbinowitsch E.,
RA   Rajandream M.A., Rutherford K.M., Rutter S., Seeger K., Saunders D.,
RA   Sharp S., Squares R., Squares S., Taylor K., Warren T., Wietzorrek A.,
RA   Woodward J.R., Barrell B.G., Parkhill J., Hopwood D.A.;
RT   "Complete genome sequence of the model actinomycete Streptomyces coelicolor
RT   A3(2).";
RL   Nature 417:141-147(2002).
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the UPF0126 family. {ECO:0000305}.
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DR   EMBL; AL939118; CAB56385.1; -; Genomic_DNA.
DR   RefSeq; NP_628284.1; NC_003888.3.
DR   RefSeq; WP_011029436.1; NZ_VNID01000030.1.
DR   AlphaFoldDB; Q9RKM3; -.
DR   SMR; Q9RKM3; -.
DR   STRING; 100226.SCO4104; -.
DR   TCDB; 1.A.62.3.2; the homotrimeric cation channel (tric) family.
DR   GeneID; 1099541; -.
DR   KEGG; sco:SCO4104; -.
DR   PATRIC; fig|100226.15.peg.4163; -.
DR   eggNOG; COG2860; Bacteria.
DR   HOGENOM; CLU_064906_1_1_11; -.
DR   InParanoid; Q9RKM3; -.
DR   OMA; YIWCILG; -.
DR   PhylomeDB; Q9RKM3; -.
DR   Proteomes; UP000001973; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IBA:GO_Central.
DR   InterPro; IPR005115; Gly_transporter.
DR   Pfam; PF03458; Gly_transporter; 2.
PE   3: Inferred from homology;
KW   Cell membrane; Membrane; Reference proteome; Transmembrane;
KW   Transmembrane helix.
FT   CHAIN           1..218
FT                   /note="UPF0126 membrane protein SCO4104"
FT                   /id="PRO_0000166308"
FT   TRANSMEM        8..28
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        37..57
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        64..84
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        91..111
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        118..138
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        154..174
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        179..199
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   218 AA;  22064 MW;  7EBDB7ADF066C9A3 CRC64;
     MSTEPAPLLA LDLTGTFAFG LNGALTAVRA ARLDVVGVVV LGMITALGGG VIRDVLIDSL
     PPAAFLDWRY YTLAAAGGLL AFAVSRHLRR LEPAITVLDA VGLSTFAVIG ASKALDAGLA
     VVPAMLLGVI TAVGGGTIRD TLVGRIPTVL RTGLYAIPAL AGAAVTVATT ETGVYGLPAA
     LGAAAVCFLI RMLGLHFGIN APEPPETRPS GGGTRRQK