Y414_MYCGE
ID Y414_MYCGE Reviewed; 1036 AA.
AC P47653; P47654; Q49457;
DT 01-FEB-1996, integrated into UniProtKB/Swiss-Prot.
DT 01-FEB-1996, sequence version 1.
DT 03-AUG-2022, entry version 93.
DE RecName: Full=Uncharacterized protein MG414;
GN OrderedLocusNames=MG414;
OS Mycoplasma genitalium (strain ATCC 33530 / DSM 19775 / NCTC 10195 / G37)
OS (Mycoplasmoides genitalium).
OC Bacteria; Tenericutes; Mollicutes; Mycoplasmataceae; Mycoplasma.
OX NCBI_TaxID=243273;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 33530 / DSM 19775 / NCTC 10195 / G37;
RX PubMed=7569993; DOI=10.1126/science.270.5235.397;
RA Fraser C.M., Gocayne J.D., White O., Adams M.D., Clayton R.A.,
RA Fleischmann R.D., Bult C.J., Kerlavage A.R., Sutton G.G., Kelley J.M.,
RA Fritchman J.L., Weidman J.F., Small K.V., Sandusky M., Fuhrmann J.L.,
RA Nguyen D.T., Utterback T.R., Saudek D.M., Phillips C.A., Merrick J.M.,
RA Tomb J.-F., Dougherty B.A., Bott K.F., Hu P.-C., Lucier T.S.,
RA Peterson S.N., Smith H.O., Hutchison C.A. III, Venter J.C.;
RT "The minimal gene complement of Mycoplasma genitalium.";
RL Science 270:397-403(1995).
RN [2]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 52-146 AND 733-833.
RC STRAIN=ATCC 33530 / DSM 19775 / NCTC 10195 / G37;
RX PubMed=8253680; DOI=10.1128/jb.175.24.7918-7930.1993;
RA Peterson S.N., Hu P.-C., Bott K.F., Hutchison C.A. III;
RT "A survey of the Mycoplasma genitalium genome by using random sequencing.";
RL J. Bacteriol. 175:7918-7930(1993).
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC protein {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the MG414/MG415 family. {ECO:0000305}.
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DR EMBL; L43967; AAC71641.1; -; Genomic_DNA.
DR EMBL; U01695; AAB01008.1; -; Genomic_DNA.
DR EMBL; U01804; AAD12330.1; -; Genomic_DNA.
DR PIR; H64245; H64245.
DR RefSeq; WP_010869473.1; NC_000908.2.
DR AlphaFoldDB; P47653; -.
DR STRING; 243273.MG_414; -.
DR PRIDE; P47653; -.
DR EnsemblBacteria; AAC71641; AAC71641; MG_414.
DR KEGG; mge:MG_414; -.
DR eggNOG; ENOG5030N8P; Bacteria.
DR HOGENOM; CLU_293346_0_0_14; -.
DR OMA; WYNNIYY; -.
DR OrthoDB; 1790207at2; -.
DR BioCyc; MGEN243273:G1GJ2-510-MON; -.
DR Proteomes; UP000000807; Chromosome.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
PE 3: Inferred from homology;
KW Cell membrane; Membrane; Reference proteome; Transmembrane;
KW Transmembrane helix.
FT CHAIN 1..1036
FT /note="Uncharacterized protein MG414"
FT /id="PRO_0000210598"
FT TRANSMEM 4..24
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 1004..1024
FT /note="Helical"
FT /evidence="ECO:0000255"
FT CONFLICT 733..736
FT /note="LEPT -> SRAS (in Ref. 2)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 1036 AA; 123180 MW; 12A21F00F686A141 CRC64;
MRSYLFIPLL VSFLFPVALA NASLEKNLVD TNLYLSPNTI QNRSYTAGFN LKNDYFRKSF
NFDNEVIQRP NQNNYFAKTY SNEWSELVNK YSDNYKQIIR DNNFHWYNNI YYLKNIKLKI
ESSYIAHAFS STFRYPGIRN SWSSDIHSEQ RFYFHSQAIS NFFPRDGHTN EKWTEVPSRN
IEITGTNPDG SWNKSWYKPD NPYFWDLTKP SHKKAYFIEA KFVHMWGSTL RMIKPTPEDV
IRNIKWLRKG NNGNYVIDFN APMWYYLGQE SRGFFADWKN NIFVAPDFWW GLAMTPIRAY
RFWWDLELVK VPPVFEQNNA QWNEPFPGRS SWFFSINSNK QVDAHWMSIN EFKEKMKKDR
KIIEAFTNNR EITQTILRLG NGLVVRPETE DSRREAFNSK WDIFKHTPIL PEQEVVHHQI
SFYLRQNNPD EVLPISFSNL SKLWISQLEF DINSLVSQTE KTLNKETIGT KIKPTIKFKD
KFINAIKEVS LINQRIDESI DKNEALKSFN ISTNNQSNFY PNLDYLYNLL QMSPNNKEEL
FFIRNLPRMV KTIFDRSTLT VKVKIGNSVN EITLLRNNKN YFDLSSIEEF LTEKQKADNE
MNIEFLALNF FVDGYESENI SNYSVEPLFD SIKKLSTIKR TKDGFEYKFK YRKDFNEQRW
IAKDFRIPLN KNVQNFNVAE LKKRNEKFND YEKRQMAFII KNSFKSKDKN IDLDINSNSL
TFVDNPKKYF KHLEPTNEKK GIFYVLAEIN NSNELFKYGS ESDSEIIKDK MYFLSQNQKN
PKLRTYLFKF HTNKLFVDKN DLGFKLEKDK VFLSVDNLKI AELDLKSSSF KFLEDYQLDF
HEPFSLNDEQ LLVDKLNITL SEKRLQTTKN VRFNLKNKFI NIHLVENKNQ FNLVFDVDVR
SKKLFIKGVN NDNQVFSISY DLKITNNQTL LIVDANGFDN SIWFDITSEN QTQLFKALSF
YLKQNNLQFK RVPDFNLKSQ DKSYEVDKLE KNEIKKQDTN VELILWVIFG IIISLMISSA
VLFLKWRKKK IVKKRN