Y4155_MYCUA
ID Y4155_MYCUA Reviewed; 310 AA.
AC A0PV26;
DT 28-JUL-2009, integrated into UniProtKB/Swiss-Prot.
DT 09-JAN-2007, sequence version 1.
DT 03-AUG-2022, entry version 79.
DE RecName: Full=Uncharacterized tRNA/rRNA methyltransferase MUL_4155;
DE EC=2.1.1.-;
GN OrderedLocusNames=MUL_4155;
OS Mycobacterium ulcerans (strain Agy99).
OC Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC Mycobacterium.
OX NCBI_TaxID=362242;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Agy99;
RX PubMed=17210928; DOI=10.1101/gr.5942807;
RA Stinear T.P., Seemann T., Pidot S., Frigui W., Reysset G., Garnier T.,
RA Meurice G., Simon D., Bouchier C., Ma L., Tichit M., Porter J.L., Ryan J.,
RA Johnson P.D.R., Davies J.K., Jenkin G.A., Small P.L.C., Jones L.M.,
RA Tekaia F., Laval F., Daffe M., Parkhill J., Cole S.T.;
RT "Reductive evolution and niche adaptation inferred from the genome of
RT Mycobacterium ulcerans, the causative agent of Buruli ulcer.";
RL Genome Res. 17:192-200(2007).
CC -!- SIMILARITY: Belongs to the class IV-like SAM-binding methyltransferase
CC superfamily. RNA methyltransferase TrmH family. {ECO:0000305}.
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DR EMBL; CP000325; ABL06195.1; -; Genomic_DNA.
DR RefSeq; WP_011741799.1; NC_008611.1.
DR AlphaFoldDB; A0PV26; -.
DR SMR; A0PV26; -.
DR STRING; 362242.MUL_4155; -.
DR EnsemblBacteria; ABL06195; ABL06195; MUL_4155.
DR KEGG; mul:MUL_4155; -.
DR eggNOG; COG0566; Bacteria.
DR HOGENOM; CLU_021322_0_0_11; -.
DR OMA; QVPPYEY; -.
DR Proteomes; UP000000765; Chromosome.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProt.
DR GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR GO; GO:0008173; F:RNA methyltransferase activity; IEA:InterPro.
DR GO; GO:0006396; P:RNA processing; IEA:InterPro.
DR Gene3D; 3.30.1330.30; -; 1.
DR Gene3D; 3.40.1280.10; -; 1.
DR InterPro; IPR029028; Alpha/beta_knot_MTases.
DR InterPro; IPR029064; L30e-like.
DR InterPro; IPR004441; rRNA_MeTrfase_TrmH.
DR InterPro; IPR001537; SpoU_MeTrfase.
DR InterPro; IPR013123; SpoU_subst-bd.
DR InterPro; IPR029026; tRNA_m1G_MTases_N.
DR PANTHER; PTHR46429; PTHR46429; 1.
DR Pfam; PF00588; SpoU_methylase; 1.
DR Pfam; PF08032; SpoU_sub_bind; 1.
DR SMART; SM00967; SpoU_sub_bind; 1.
DR SUPFAM; SSF55315; SSF55315; 1.
DR SUPFAM; SSF75217; SSF75217; 1.
DR TIGRFAMs; TIGR00186; rRNA_methyl_3; 1.
PE 3: Inferred from homology;
KW Methyltransferase; S-adenosyl-L-methionine; Transferase.
FT CHAIN 1..310
FT /note="Uncharacterized tRNA/rRNA methyltransferase
FT MUL_4155"
FT /id="PRO_0000379583"
FT REGION 1..70
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT BINDING 262
FT /ligand="S-adenosyl-L-methionine"
FT /ligand_id="ChEBI:CHEBI:59789"
FT /evidence="ECO:0000250"
FT BINDING 282
FT /ligand="S-adenosyl-L-methionine"
FT /ligand_id="ChEBI:CHEBI:59789"
FT /evidence="ECO:0000250"
FT BINDING 291
FT /ligand="S-adenosyl-L-methionine"
FT /ligand_id="ChEBI:CHEBI:59789"
FT /evidence="ECO:0000250"
SQ SEQUENCE 310 AA; 32498 MW; 7DD281419596F7DE CRC64;
MAGNSQRRGA IRKSGTKKGT SVGSGGQRRR GLEGRGPTPS AHMRPNHPAA KRAKAQQRRP
ARGRTDETET VLGRNPVLEC LRAGVPSTAL YVALGVEADE RLTESVSRAA DSGIPILEVP
RTDLDRMTAN HLHQGIALQV PPYNYAHPDD LLAAALDTPP ALLVALDNIS DPRNLGAIVR
SVAAFGGHGV LIPQRRSASV TAVAWRTSAG AAARMPVARA TNLTRALKDW ADRGVRVVGL
DAGGDTAIDD LDGSDPIVVV VGSEGKGLSR LVRQTCDEVV SVPMAGPTES LNASVAAGVV
LAEIARQRRT
