Y4188_BRUSU
ID Y4188_BRUSU Reviewed; 250 AA.
AC Q8FUN2; G0KEI4;
DT 17-APR-2007, integrated into UniProtKB/Swiss-Prot.
DT 01-MAR-2003, sequence version 1.
DT 25-MAY-2022, entry version 93.
DE RecName: Full=Probable ABC transporter permease protein BRA1188/BS1330_II1179;
GN OrderedLocusNames=BRA1188, BS1330_II1179;
OS Brucella suis biovar 1 (strain 1330).
OC Bacteria; Proteobacteria; Alphaproteobacteria; Hyphomicrobiales;
OC Brucellaceae; Brucella/Ochrobactrum group; Brucella.
OX NCBI_TaxID=204722;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=1330;
RX PubMed=12271122; DOI=10.1073/pnas.192319099;
RA Paulsen I.T., Seshadri R., Nelson K.E., Eisen J.A., Heidelberg J.F.,
RA Read T.D., Dodson R.J., Umayam L.A., Brinkac L.M., Beanan M.J.,
RA Daugherty S.C., DeBoy R.T., Durkin A.S., Kolonay J.F., Madupu R.,
RA Nelson W.C., Ayodeji B., Kraul M., Shetty J., Malek J.A., Van Aken S.E.,
RA Riedmuller S., Tettelin H., Gill S.R., White O., Salzberg S.L.,
RA Hoover D.L., Lindler L.E., Halling S.M., Boyle S.M., Fraser C.M.;
RT "The Brucella suis genome reveals fundamental similarities between animal
RT and plant pathogens and symbionts.";
RL Proc. Natl. Acad. Sci. U.S.A. 99:13148-13153(2002).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=1330;
RX PubMed=22038969; DOI=10.1128/jb.06181-11;
RA Tae H., Shallom S., Settlage R., Preston D., Adams L.G., Garner H.R.;
RT "Revised genome sequence of Brucella suis 1330.";
RL J. Bacteriol. 193:6410-6410(2011).
CC -!- FUNCTION: Probably part of an ABC transporter complex. Probably
CC responsible for the translocation of the substrate across the membrane
CC (Probable). {ECO:0000305}.
CC -!- SUBUNIT: The complex is composed of two ATP-binding proteins (BRA1187),
CC two transmembrane proteins (BRA1188) and a solute-binding protein
CC (BRA1186). {ECO:0000305}.
CC -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000305}; Multi-pass
CC membrane protein {ECO:0000255|PROSITE-ProRule:PRU00441}.
CC -!- SIMILARITY: Belongs to the binding-protein-dependent transport system
CC permease family. {ECO:0000305}.
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DR EMBL; AE014292; AAN34346.1; -; Genomic_DNA.
DR EMBL; CP002998; AEM20622.1; -; Genomic_DNA.
DR RefSeq; WP_006191541.1; NZ_KN046805.1.
DR AlphaFoldDB; Q8FUN2; -.
DR SMR; Q8FUN2; -.
DR EnsemblBacteria; AEM20622; AEM20622; BS1330_II1179.
DR GeneID; 45054169; -.
DR KEGG; bms:BRA1188; -.
DR KEGG; bsi:BS1330_II1179; -.
DR PATRIC; fig|204722.21.peg.280; -.
DR HOGENOM; CLU_046113_1_0_5; -.
DR OMA; LIEFYRP; -.
DR PhylomeDB; Q8FUN2; -.
DR Proteomes; UP000007104; Chromosome II.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0055085; P:transmembrane transport; IEA:InterPro.
DR CDD; cd06261; TM_PBP2; 1.
DR Gene3D; 1.10.3720.10; -; 1.
DR InterPro; IPR000515; MetI-like.
DR InterPro; IPR035906; MetI-like_sf.
DR Pfam; PF00528; BPD_transp_1; 1.
DR SUPFAM; SSF161098; SSF161098; 1.
DR PROSITE; PS50928; ABC_TM1; 1.
PE 3: Inferred from homology;
KW Cell inner membrane; Cell membrane; Membrane; Transmembrane;
KW Transmembrane helix; Transport.
FT CHAIN 1..250
FT /note="Probable ABC transporter permease protein
FT BRA1188/BS1330_II1179"
FT /id="PRO_0000284088"
FT TRANSMEM 12..32
FT /note="Helical"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT TRANSMEM 63..83
FT /note="Helical"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT TRANSMEM 94..114
FT /note="Helical"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT TRANSMEM 122..142
FT /note="Helical"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT TRANSMEM 172..192
FT /note="Helical"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT TRANSMEM 211..231
FT /note="Helical"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT DOMAIN 56..236
FT /note="ABC transmembrane type-1"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
SQ SEQUENCE 250 AA; 26879 MW; 3EF10C2447568BB0 CRC64;
MNARLTGLGL NLLSFAVGIG GWYLLTATGA VVLPGPVDVL ERAVTLLLNG QLVGDIFASL
RRVLSGFVLG VALAIPVGFL MGWYRIARSP IEPWVQFFRM IPPLAVIPLA IVTLGIDESP
KIFVIFLASF LSSVVATYQG VISVDRTLIN AARVLGAKDA TIFARVIVPA SVPFILVGVR
IGLGSAWATV VAAELIAAQS GLGYRMQQAQ LYYDLPTIFV SLVTIGILGL FMDRLLQAAD
RRLTQWQERA
