ID   Y421_METJA              Reviewed;         360 AA.
AC   Q57864;
DT   01-NOV-1997, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1996, sequence version 1.
DT   25-MAY-2022, entry version 88.
DE   RecName: Full=Uncharacterized protein MJ0421;
GN   OrderedLocusNames=MJ0421;
OS   Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM
OS   10045 / NBRC 100440) (Methanococcus jannaschii).
OC   Archaea; Euryarchaeota; Methanomada group; Methanococci; Methanococcales;
OC   Methanocaldococcaceae; Methanocaldococcus.
OX   NCBI_TaxID=243232;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440;
RX   PubMed=8688087; DOI=10.1126/science.273.5278.1058;
RA   Bult C.J., White O., Olsen G.J., Zhou L., Fleischmann R.D., Sutton G.G.,
RA   Blake J.A., FitzGerald L.M., Clayton R.A., Gocayne J.D., Kerlavage A.R.,
RA   Dougherty B.A., Tomb J.-F., Adams M.D., Reich C.I., Overbeek R.,
RA   Kirkness E.F., Weinstock K.G., Merrick J.M., Glodek A., Scott J.L.,
RA   Geoghagen N.S.M., Weidman J.F., Fuhrmann J.L., Nguyen D., Utterback T.R.,
RA   Kelley J.M., Peterson J.D., Sadow P.W., Hanna M.C., Cotton M.D.,
RA   Roberts K.M., Hurst M.A., Kaine B.P., Borodovsky M., Klenk H.-P.,
RA   Fraser C.M., Smith H.O., Woese C.R., Venter J.C.;
RT   "Complete genome sequence of the methanogenic archaeon, Methanococcus
RT   jannaschii.";
RL   Science 273:1058-1073(1996).
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DR   EMBL; L77117; AAB98409.1; -; Genomic_DNA.
DR   PIR; E64352; E64352.
DR   RefSeq; WP_010869920.1; NC_000909.1.
DR   AlphaFoldDB; Q57864; -.
DR   SMR; Q57864; -.
DR   STRING; 243232.MJ_0421; -.
DR   EnsemblBacteria; AAB98409; AAB98409; MJ_0421.
DR   GeneID; 1451281; -.
DR   KEGG; mja:MJ_0421; -.
DR   eggNOG; arCOG00056; Archaea.
DR   HOGENOM; CLU_795999_0_0_2; -.
DR   InParanoid; Q57864; -.
DR   OMA; ESRYQIQ; -.
DR   OrthoDB; 27531at2157; -.
DR   PhylomeDB; Q57864; -.
DR   Proteomes; UP000000805; Chromosome.
DR   GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR   GO; GO:0016423; F:tRNA (guanine) methyltransferase activity; IBA:GO_Central.
DR   GO; GO:0030488; P:tRNA methylation; IBA:GO_Central.
DR   CDD; cd11718; THUMP_SPOUT; 1.
DR   InterPro; IPR029028; Alpha/beta_knot_MTases.
DR   InterPro; IPR041730; MJ0421-like_THUMP.
DR   InterPro; IPR025849; SPOUT_MTase_fused_to_THUMP.
DR   InterPro; IPR004114; THUMP_dom.
DR   Pfam; PF14419; SPOUT_MTase_2; 1.
DR   Pfam; PF02926; THUMP; 1.
DR   SMART; SM00981; THUMP; 1.
DR   SUPFAM; SSF75217; SSF75217; 1.
DR   PROSITE; PS51165; THUMP; 1.
PE   4: Predicted;
KW   Reference proteome.
FT   CHAIN           1..360
FT                   /note="Uncharacterized protein MJ0421"
FT                   /id="PRO_0000106867"
FT   DOMAIN          45..148
FT                   /note="THUMP"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00529"
SQ   SEQUENCE   360 AA;  41397 MW;  6C268E2E09D2753B CRC64;
     MKFIIKTQKG FENIVVNNLK EIVDDFNYIV SPDGYQGIVI VESDEDIEDK ILQIPEVERV
     LKVYFETETD FDKIVNLAEK IKDYIKEDET FAVETKKRGK HDFSSTDINI VLGAKIKDLT
     NASVDLNNPD KVVHVEVFKN KTYVSITPGE KFKKYTKEKR NARELFKKVV IVQMPYLGEK
     IVCKRFGEAI GRAAQGFEVK ELIIAPKEKV DAYELMEFIK GVKIGQHSRY EIQKRAYPFE
     IKLVPVTVQD LYQVVRDKRR DNRLLIITDP KGDELSKIKD KLAYDLRKKR EIIVFCGSRE
     GIPRGLFRFA DYIVDLAPHM TFATEHAIPA ALIALWGVYS GEDLENSSKE EKTESNSNGE