ID   Y4223_DICDI             Reviewed;         260 AA.
AC   Q8SSU2; Q554S8;
DT   10-FEB-2009, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-2002, sequence version 1.
DT   25-MAY-2022, entry version 102.
DE   RecName: Full=Glutathione S-transferase domain-containing protein DDB_G0274223;
GN   ORFNames=DDB_G0274223;
OS   Dictyostelium discoideum (Slime mold).
OC   Eukaryota; Amoebozoa; Evosea; Eumycetozoa; Dictyostelia; Dictyosteliales;
OC   Dictyosteliaceae; Dictyostelium.
OX   NCBI_TaxID=44689;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=AX4;
RX   PubMed=12097910; DOI=10.1038/nature00847;
RA   Gloeckner G., Eichinger L., Szafranski K., Pachebat J.A., Bankier A.T.,
RA   Dear P.H., Lehmann R., Baumgart C., Parra G., Abril J.F., Guigo R.,
RA   Kumpf K., Tunggal B., Cox E.C., Quail M.A., Platzer M., Rosenthal A.,
RA   Noegel A.A.;
RT   "Sequence and analysis of chromosome 2 of Dictyostelium discoideum.";
RL   Nature 418:79-85(2002).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=AX4;
RX   PubMed=15875012; DOI=10.1038/nature03481;
RA   Eichinger L., Pachebat J.A., Gloeckner G., Rajandream M.A., Sucgang R.,
RA   Berriman M., Song J., Olsen R., Szafranski K., Xu Q., Tunggal B.,
RA   Kummerfeld S., Madera M., Konfortov B.A., Rivero F., Bankier A.T.,
RA   Lehmann R., Hamlin N., Davies R., Gaudet P., Fey P., Pilcher K., Chen G.,
RA   Saunders D., Sodergren E.J., Davis P., Kerhornou A., Nie X., Hall N.,
RA   Anjard C., Hemphill L., Bason N., Farbrother P., Desany B., Just E.,
RA   Morio T., Rost R., Churcher C.M., Cooper J., Haydock S., van Driessche N.,
RA   Cronin A., Goodhead I., Muzny D.M., Mourier T., Pain A., Lu M., Harper D.,
RA   Lindsay R., Hauser H., James K.D., Quiles M., Madan Babu M., Saito T.,
RA   Buchrieser C., Wardroper A., Felder M., Thangavelu M., Johnson D.,
RA   Knights A., Loulseged H., Mungall K.L., Oliver K., Price C., Quail M.A.,
RA   Urushihara H., Hernandez J., Rabbinowitsch E., Steffen D., Sanders M.,
RA   Ma J., Kohara Y., Sharp S., Simmonds M.N., Spiegler S., Tivey A.,
RA   Sugano S., White B., Walker D., Woodward J.R., Winckler T., Tanaka Y.,
RA   Shaulsky G., Schleicher M., Weinstock G.M., Rosenthal A., Cox E.C.,
RA   Chisholm R.L., Gibbs R.A., Loomis W.F., Platzer M., Kay R.R.,
RA   Williams J.G., Dear P.H., Noegel A.A., Barrell B.G., Kuspa A.;
RT   "The genome of the social amoeba Dictyostelium discoideum.";
RL   Nature 435:43-57(2005).
CC   -!- SIMILARITY: Belongs to the GST superfamily. {ECO:0000305}.
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DR   EMBL; AAFI02000012; EAL70004.1; -; Genomic_DNA.
DR   RefSeq; XP_644245.1; XM_639153.1.
DR   AlphaFoldDB; Q8SSU2; -.
DR   SMR; Q8SSU2; -.
DR   STRING; 44689.DDB0304357; -.
DR   PaxDb; Q8SSU2; -.
DR   EnsemblProtists; EAL70004; EAL70004; DDB_G0274223.
DR   GeneID; 8619673; -.
DR   KEGG; ddi:DDB_G0274223; -.
DR   dictyBase; DDB_G0274223; -.
DR   eggNOG; KOG0867; Eukaryota.
DR   HOGENOM; CLU_011226_14_4_1; -.
DR   InParanoid; Q8SSU2; -.
DR   OMA; DFAILGW; -.
DR   PhylomeDB; Q8SSU2; -.
DR   PRO; PR:Q8SSU2; -.
DR   Proteomes; UP000002195; Chromosome 2.
DR   GO; GO:0006749; P:glutathione metabolic process; IEA:InterPro.
DR   InterPro; IPR010987; Glutathione-S-Trfase_C-like.
DR   InterPro; IPR036282; Glutathione-S-Trfase_C_sf.
DR   InterPro; IPR040079; Glutathione_S-Trfase.
DR   InterPro; IPR004045; Glutathione_S-Trfase_N.
DR   InterPro; IPR004046; GST_C.
DR   InterPro; IPR036249; Thioredoxin-like_sf.
DR   Pfam; PF00043; GST_C; 1.
DR   Pfam; PF02798; GST_N; 1.
DR   SFLD; SFLDS00019; Glutathione_Transferase_(cytos; 1.
DR   SUPFAM; SSF47616; SSF47616; 1.
DR   SUPFAM; SSF52833; SSF52833; 1.
DR   PROSITE; PS50405; GST_CTER; 1.
DR   PROSITE; PS50404; GST_NTER; 1.
PE   3: Inferred from homology;
KW   Reference proteome.
FT   CHAIN           1..260
FT                   /note="Glutathione S-transferase domain-containing protein
FT                   DDB_G0274223"
FT                   /id="PRO_0000363845"
FT   DOMAIN          7..96
FT                   /note="GST N-terminal"
FT   DOMAIN          102..233
FT                   /note="GST C-terminal"
SQ   SEQUENCE   260 AA;  30155 MW;  EFA802ECED377488 CRC64;
     MIEINNKVDY IFYTNNTPNT YKIKLILLEL EKKHSITFES RYINITKKEN YSDEFVKINP
     NKKVPAIVDQ TGEKPFVVFE SVSILIYLAQ KYNTFLPDFK TNPHENSDVI TWAVWQAANL
     GPAFGQYFHF SYFSPTVQEY SLHRFNNEAQ RVLRLLDDRL SVSQYIGGNE FSIADIASAG
     WLLYLNFAPI YKATKERFPH IFKWLDLINQ RDAVKEINQS ISEGFKTFNP SALRALFTDD
     PELINAKAPI GIENVVLKYD