ID   Y4236_MYCA1             Reviewed;         304 AA.
AC   A0QKD9;
DT   20-JAN-2009, integrated into UniProtKB/Swiss-Prot.
DT   09-JAN-2007, sequence version 1.
DT   03-AUG-2022, entry version 69.
DE   RecName: Full=Putative S-adenosyl-L-methionine-dependent methyltransferase MAV_4236;
DE            EC=2.1.1.-;
GN   OrderedLocusNames=MAV_4236;
OS   Mycobacterium avium (strain 104).
OC   Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC   Mycobacterium; Mycobacterium avium complex (MAC).
OX   NCBI_TaxID=243243;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=104;
RA   Fleischmann R.D., Dodson R.J., Haft D.H., Merkel J.S., Nelson W.C.,
RA   Fraser C.M.;
RL   Submitted (OCT-2006) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Exhibits S-adenosyl-L-methionine-dependent methyltransferase
CC       activity. {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the UPF0677 family. {ECO:0000305}.
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DR   EMBL; CP000479; ABK64486.1; -; Genomic_DNA.
DR   RefSeq; WP_009978767.1; NC_008595.1.
DR   AlphaFoldDB; A0QKD9; -.
DR   SMR; A0QKD9; -.
DR   EnsemblBacteria; ABK64486; ABK64486; MAV_4236.
DR   GeneID; 66695436; -.
DR   KEGG; mav:MAV_4236; -.
DR   HOGENOM; CLU_056160_2_1_11; -.
DR   OMA; GMQRMTD; -.
DR   OrthoDB; 847145at2; -.
DR   Proteomes; UP000001574; Chromosome.
DR   GO; GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
DR   GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR   Gene3D; 3.40.50.150; -; 1.
DR   InterPro; IPR011610; CHP00027_methylltransferase.
DR   InterPro; IPR007213; Ppm1/Ppm2/Tcmp.
DR   InterPro; IPR029063; SAM-dependent_MTases_sf.
DR   Pfam; PF04072; LCM; 1.
DR   SUPFAM; SSF53335; SSF53335; 1.
DR   TIGRFAMs; TIGR00027; mthyl_TIGR00027; 1.
PE   3: Inferred from homology;
KW   Methyltransferase; S-adenosyl-L-methionine; Transferase.
FT   CHAIN           1..304
FT                   /note="Putative S-adenosyl-L-methionine-dependent
FT                   methyltransferase MAV_4236"
FT                   /id="PRO_0000361106"
FT   BINDING         129
FT                   /ligand="S-adenosyl-L-methionine"
FT                   /ligand_id="ChEBI:CHEBI:59789"
FT                   /evidence="ECO:0000250"
FT   BINDING         158..159
FT                   /ligand="S-adenosyl-L-methionine"
FT                   /ligand_id="ChEBI:CHEBI:59789"
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   304 AA;  32376 MW;  B558BC8C0A6960B6 CRC64;
     MARTDDDTWD LATSVGATAT MVAAGRARAT RDGLIDDPFA EPLVRAVGVD FFTRWAAGEL
     DAADVDVPGA AWGMQRMTDM ITARTRYIDA FFAEAGAAGI RQVVILASGL DARAYRLPWP
     AGTTVFEIDQ PRVLEFKAAT IAQLGAEPTA PVRAVAVDLR HDWPSALRQA GFDVGRPAAW
     AAEGLLGFLP PQAQDRLLDN VTALSADGSQ LVAEVFANTG ASGDALNAAG EKWRRHGLDV
     ALDDLGFPGE RNDPASYLQQ LGWQPVRTPL NQMLANNGLP LQSTEPGAPF AQNYYCTAVL
     NKAG