ID   Y423_MYCGE              Reviewed;         561 AA.
AC   P47662; Q49470; Q49480;
DT   01-FEB-1996, integrated into UniProtKB/Swiss-Prot.
DT   01-FEB-1996, sequence version 1.
DT   03-AUG-2022, entry version 116.
DE   RecName: Full=Uncharacterized protein MG423;
GN   OrderedLocusNames=MG423;
OS   Mycoplasma genitalium (strain ATCC 33530 / DSM 19775 / NCTC 10195 / G37)
OS   (Mycoplasmoides genitalium).
OC   Bacteria; Tenericutes; Mollicutes; Mycoplasmataceae; Mycoplasma.
OX   NCBI_TaxID=243273;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 33530 / DSM 19775 / NCTC 10195 / G37;
RX   PubMed=7569993; DOI=10.1126/science.270.5235.397;
RA   Fraser C.M., Gocayne J.D., White O., Adams M.D., Clayton R.A.,
RA   Fleischmann R.D., Bult C.J., Kerlavage A.R., Sutton G.G., Kelley J.M.,
RA   Fritchman J.L., Weidman J.F., Small K.V., Sandusky M., Fuhrmann J.L.,
RA   Nguyen D.T., Utterback T.R., Saudek D.M., Phillips C.A., Merrick J.M.,
RA   Tomb J.-F., Dougherty B.A., Bott K.F., Hu P.-C., Lucier T.S.,
RA   Peterson S.N., Smith H.O., Hutchison C.A. III, Venter J.C.;
RT   "The minimal gene complement of Mycoplasma genitalium.";
RL   Science 270:397-403(1995).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 55-138 AND 400-478.
RC   STRAIN=ATCC 33530 / DSM 19775 / NCTC 10195 / G37;
RX   PubMed=1945886; DOI=10.1093/nar/19.21.6027;
RA   Peterson S.N., Schramm N., Hu P.-C., Bott K.F., Hutchison C.A. III;
RT   "A random sequencing approach for placing markers on the physical map of
RT   Mycoplasma genitalium.";
RL   Nucleic Acids Res. 19:6027-6031(1991).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 486-561.
RC   STRAIN=ATCC 33530 / DSM 19775 / NCTC 10195 / G37;
RX   PubMed=8253680; DOI=10.1128/jb.175.24.7918-7930.1993;
RA   Peterson S.N., Hu P.-C., Bott K.F., Hutchison C.A. III;
RT   "A survey of the Mycoplasma genitalium genome by using random sequencing.";
RL   J. Bacteriol. 175:7918-7930(1993).
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
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DR   EMBL; L43967; AAC71647.1; -; Genomic_DNA.
DR   EMBL; X61510; CAB97509.1; -; Genomic_DNA.
DR   EMBL; X61524; CAB98129.1; -; Genomic_DNA.
DR   EMBL; U02228; AAA03380.1; -; Genomic_DNA.
DR   PIR; G64246; G64246.
DR   RefSeq; WP_010869479.1; NC_000908.2.
DR   AlphaFoldDB; P47662; -.
DR   SMR; P47662; -.
DR   STRING; 243273.MG_423; -.
DR   EnsemblBacteria; AAC71647; AAC71647; MG_423.
DR   KEGG; mge:MG_423; -.
DR   eggNOG; COG0595; Bacteria.
DR   HOGENOM; CLU_008727_3_2_14; -.
DR   OMA; PWLLMKI; -.
DR   OrthoDB; 580619at2; -.
DR   BioCyc; MGEN243273:G1GJ2-517-MON; -.
DR   Proteomes; UP000000807; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0046872; F:metal ion binding; IEA:InterPro.
DR   GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR   Gene3D; 3.40.50.10710; -; 1.
DR   Gene3D; 3.60.15.10; -; 1.
DR   InterPro; IPR036866; RibonucZ/Hydroxyglut_hydro.
DR   InterPro; IPR004613; RNase_J.
DR   InterPro; IPR042173; RNase_J_2.
DR   InterPro; IPR041636; RNase_J_C.
DR   Pfam; PF17770; RNase_J_C; 1.
DR   SUPFAM; SSF56281; SSF56281; 1.
DR   TIGRFAMs; TIGR00649; MG423; 1.
PE   4: Predicted;
KW   Cell membrane; Membrane; Reference proteome; Transmembrane;
KW   Transmembrane helix.
FT   CHAIN           1..561
FT                   /note="Uncharacterized protein MG423"
FT                   /id="PRO_0000210604"
FT   TRANSMEM        29..49
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        80..100
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   CONFLICT        136..138
FT                   /note="PFK -> LLR (in Ref. 2)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        403
FT                   /note="A -> R (in Ref. 2)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   561 AA;  63397 MW;  5FE18E9D7BDC9FEA CRC64;
     MAKIKFFALG GQDERGKNCY VLEIDNDVFI FNVGSLTPTT AVLGVKKIIP DFSWIQENQA
     RVKGIFIGNA ITENLGSLEF LFHTVGFFPI YTSSIGASII KSKINENKLN IARDKLEIHE
     LKPLETIEIS NHSITPFKVS SSLPSSFGFA LNTDNGYIVF IDDFIVLNDK NIAFENQLNQ
     IIPKLSDNTL LLITGVGLVG RNSGFTTPKH KSLEQLNRII TPAKGRIFVA CYDSNAYSVM
     TLAQIARMQN RPFIIYSQSF VHLFNTIVRQ KLFNNTHLNT ISIEEINNST NSIVVLTSPP
     DKLYAKLFKI GMNEDERIRY RKSDTFIFMT PKVAGYEEIE AQILDDIARN EVSYYNLGRE
     ILSIQASDED MKFLVSSLKP KYIIPTGGLY RDFINFTMVL KQAGAEQNQI LILFNGEVLT
     IENKKLDSKK NELKLNPKCV DSAGLQEIGA SIMFERDQMS ESGVVIIIIY FDQKKSEFLN
     EITYSFLGVS LDVPEKDKLK TKMEELIKKQ INDIKDFTTI KKRIGKEISK ELKVSIKRAV
     MNLFTKMTSK APLILSTIIS I