ID   Y423_THESM              Reviewed;         126 AA.
AC   C6A1J4;
DT   22-SEP-2009, integrated into UniProtKB/Swiss-Prot.
DT   01-SEP-2009, sequence version 1.
DT   03-AUG-2022, entry version 59.
DE   RecName: Full=UPF0292 protein TSIB_0423 {ECO:0000255|HAMAP-Rule:MF_01095};
GN   OrderedLocusNames=TSIB_0423;
OS   Thermococcus sibiricus (strain DSM 12597 / MM 739).
OC   Archaea; Euryarchaeota; Thermococci; Thermococcales; Thermococcaceae;
OC   Thermococcus.
OX   NCBI_TaxID=604354;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 12597 / MM 739;
RX   PubMed=19447963; DOI=10.1128/aem.00718-09;
RA   Mardanov A.V., Ravin N.V., Svetlitchnyi V.A., Beletsky A.V.,
RA   Miroshnichenko M.L., Bonch-Osmolovskaya E.A., Skryabin K.G.;
RT   "Metabolic versatility and indigenous origin of the archaeon Thermococcus
RT   sibiricus, isolated from a siberian oil reservoir, as revealed by genome
RT   analysis.";
RL   Appl. Environ. Microbiol. 75:4580-4588(2009).
CC   -!- COFACTOR:
CC       Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
CC         Evidence={ECO:0000255|HAMAP-Rule:MF_01095};
CC       Note=Binds two Mg(2+) per subunit. {ECO:0000255|HAMAP-Rule:MF_01095};
CC   -!- SIMILARITY: Belongs to the UPF0292 family. {ECO:0000255|HAMAP-
CC       Rule:MF_01095}.
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DR   EMBL; CP001463; ACS89489.1; -; Genomic_DNA.
DR   RefSeq; WP_015848709.1; NC_012883.1.
DR   AlphaFoldDB; C6A1J4; -.
DR   SMR; C6A1J4; -.
DR   STRING; 604354.TSIB_0423; -.
DR   EnsemblBacteria; ACS89489; ACS89489; TSIB_0423.
DR   GeneID; 8095409; -.
DR   KEGG; tsi:TSIB_0423; -.
DR   eggNOG; arCOG01486; Archaea.
DR   HOGENOM; CLU_140789_3_0_2; -.
DR   OMA; VMILTDF; -.
DR   Proteomes; UP000009079; Chromosome.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   CDD; cd01027; TOPRIM_RNase_M5_like; 1.
DR   HAMAP; MF_01095; UPF0292; 1.
DR   InterPro; IPR006171; TOPRIM_domain.
DR   InterPro; IPR034141; TOPRIM_RNase_M5-like.
DR   InterPro; IPR022972; UPF0292.
DR   Pfam; PF01751; Toprim; 1.
DR   SMART; SM00493; TOPRIM; 1.
DR   PROSITE; PS50880; TOPRIM; 1.
PE   3: Inferred from homology;
KW   Magnesium; Metal-binding; Reference proteome.
FT   CHAIN           1..126
FT                   /note="UPF0292 protein TSIB_0423"
FT                   /id="PRO_1000213542"
FT   DOMAIN          20..100
FT                   /note="Toprim"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01095"
FT   BINDING         26
FT                   /ligand="Mg(2+)"
FT                   /ligand_id="ChEBI:CHEBI:18420"
FT                   /ligand_label="1"
FT                   /ligand_note="catalytic"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01095"
FT   BINDING         69
FT                   /ligand="Mg(2+)"
FT                   /ligand_id="ChEBI:CHEBI:18420"
FT                   /ligand_label="1"
FT                   /ligand_note="catalytic"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01095"
FT   BINDING         69
FT                   /ligand="Mg(2+)"
FT                   /ligand_id="ChEBI:CHEBI:18420"
FT                   /ligand_label="2"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01095"
FT   BINDING         71
FT                   /ligand="Mg(2+)"
FT                   /ligand_id="ChEBI:CHEBI:18420"
FT                   /ligand_label="2"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01095"
SQ   SEQUENCE   126 AA;  14889 MW;  5F3AD08C390D8DEB CRC64;
     MYAENYKRLE QLIDKLREFN GVILVEGMRD EVALRKLGVE TEIIKLSRFP LAEIALTASH
     YHDIMILTDF DRKGEDLAKK LTQYLEGYKC RVDTNTRREL KKIAKKDIKG IEDLYGLYLR
     FKSLRF