ID   Y429_METAC              Reviewed;         396 AA.
AC   Q8TTK2;
DT   04-AUG-2003, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-2002, sequence version 1.
DT   25-MAY-2022, entry version 86.
DE   RecName: Full=Putative nickel insertion protein {ECO:0000255|HAMAP-Rule:MF_01074};
GN   OrderedLocusNames=MA_0429;
OS   Methanosarcina acetivorans (strain ATCC 35395 / DSM 2834 / JCM 12185 /
OS   C2A).
OC   Archaea; Euryarchaeota; Stenosarchaea group; Methanomicrobia;
OC   Methanosarcinales; Methanosarcinaceae; Methanosarcina.
OX   NCBI_TaxID=188937;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 35395 / DSM 2834 / JCM 12185 / C2A;
RX   PubMed=11932238; DOI=10.1101/gr.223902;
RA   Galagan J.E., Nusbaum C., Roy A., Endrizzi M.G., Macdonald P., FitzHugh W.,
RA   Calvo S., Engels R., Smirnov S., Atnoor D., Brown A., Allen N., Naylor J.,
RA   Stange-Thomann N., DeArellano K., Johnson R., Linton L., McEwan P.,
RA   McKernan K., Talamas J., Tirrell A., Ye W., Zimmer A., Barber R.D.,
RA   Cann I., Graham D.E., Grahame D.A., Guss A.M., Hedderich R.,
RA   Ingram-Smith C., Kuettner H.C., Krzycki J.A., Leigh J.A., Li W., Liu J.,
RA   Mukhopadhyay B., Reeve J.N., Smith K., Springer T.A., Umayam L.A.,
RA   White O., White R.H., de Macario E.C., Ferry J.G., Jarrell K.F., Jing H.,
RA   Macario A.J.L., Paulsen I.T., Pritchett M., Sowers K.R., Swanson R.V.,
RA   Zinder S.H., Lander E., Metcalf W.W., Birren B.;
RT   "The genome of Methanosarcina acetivorans reveals extensive metabolic and
RT   physiological diversity.";
RL   Genome Res. 12:532-542(2002).
CC   -!- SIMILARITY: Belongs to the LarC family. {ECO:0000255|HAMAP-
CC       Rule:MF_01074}.
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DR   EMBL; AE010299; AAM03876.1; -; Genomic_DNA.
DR   RefSeq; WP_011020481.1; NC_003552.1.
DR   AlphaFoldDB; Q8TTK2; -.
DR   SMR; Q8TTK2; -.
DR   STRING; 188937.MA_0429; -.
DR   EnsemblBacteria; AAM03876; AAM03876; MA_0429.
DR   GeneID; 1472321; -.
DR   KEGG; mac:MA_0429; -.
DR   HOGENOM; CLU_028523_2_1_2; -.
DR   InParanoid; Q8TTK2; -.
DR   OMA; TCLGLDW; -.
DR   OrthoDB; 69338at2157; -.
DR   PhylomeDB; Q8TTK2; -.
DR   Proteomes; UP000002487; Chromosome.
DR   GO; GO:0016829; F:lyase activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0016151; F:nickel cation binding; IEA:UniProtKB-UniRule.
DR   HAMAP; MF_01074; LarC; 1.
DR   InterPro; IPR002822; Ni_insertion.
DR   PANTHER; PTHR36566; PTHR36566; 1.
DR   Pfam; PF01969; DUF111; 1.
DR   TIGRFAMs; TIGR00299; TIGR00299; 1.
PE   3: Inferred from homology;
KW   Nickel; Reference proteome.
FT   CHAIN           1..396
FT                   /note="Putative nickel insertion protein"
FT                   /id="PRO_0000146859"
SQ   SEQUENCE   396 AA;  42467 MW;  C7D855F952D59D56 CRC64;
     MKTLVFNPFS GAAGDMILAC ALDLGADKQA VKELVEASAP VSMDIREVVK EGIKALDVRI
     KVPENEHVRT YPEIVDLVKA AKLPLQLEAS TLSIFLKMAE AEAAVHGQPD LEMLHFHEVG
     QSDALADVIG SSAALHSLNC DSVYCTPINV GSGTIECAHG TLPVPAPATL EILRKGKLYF
     RGGSVNKELL TPTGAAILSH FAKPVETFPQ GKAIAIGYGA GNADLPGPNV LQGVLLEPDS
     HLISDIIEVL ETNADDVSGE VLGNLFEELL SMGARDVAIM PATMKKGRPA HIIKVIAKPE
     DSAKLARKII VETGSLGVRV MPARHRLMAA RNIERIKIEL EGQEFETAVK VARDSEGVLL
     NISAEFEDCK KIAKASGIPV REIMRRTEEV ARKLFS