ID   Y432_LISMO              Reviewed;         248 AA.
AC   P25145;
DT   01-MAY-1992, integrated into UniProtKB/Swiss-Prot.
DT   05-DEC-2001, sequence version 2.
DT   03-AUG-2022, entry version 122.
DE   RecName: Full=Uncharacterized oxidoreductase Lmo0432;
DE            EC=1.-.-.-;
DE   AltName: Full=ORFA;
GN   OrderedLocusNames=lmo0432;
OS   Listeria monocytogenes serovar 1/2a (strain ATCC BAA-679 / EGD-e).
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Listeriaceae; Listeria.
OX   NCBI_TaxID=169963;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=EGD / Serovar 1/2a;
RX   PubMed=1905979; DOI=10.1016/0092-8674(91)90009-n;
RA   Gaillard J.-L., Berche P., Frehel C., Gouin E., Cossart P.;
RT   "Entry of L. monocytogenes into cells is mediated by internalin, a repeat
RT   protein reminiscent of surface antigens from Gram-positive cocci.";
RL   Cell 65:1127-1141(1991).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC BAA-679 / EGD-e;
RX   PubMed=11679669; DOI=10.1126/science.1063447;
RA   Glaser P., Frangeul L., Buchrieser C., Rusniok C., Amend A., Baquero F.,
RA   Berche P., Bloecker H., Brandt P., Chakraborty T., Charbit A.,
RA   Chetouani F., Couve E., de Daruvar A., Dehoux P., Domann E.,
RA   Dominguez-Bernal G., Duchaud E., Durant L., Dussurget O., Entian K.-D.,
RA   Fsihi H., Garcia-del Portillo F., Garrido P., Gautier L., Goebel W.,
RA   Gomez-Lopez N., Hain T., Hauf J., Jackson D., Jones L.-M., Kaerst U.,
RA   Kreft J., Kuhn M., Kunst F., Kurapkat G., Madueno E., Maitournam A.,
RA   Mata Vicente J., Ng E., Nedjari H., Nordsiek G., Novella S., de Pablos B.,
RA   Perez-Diaz J.-C., Purcell R., Remmel B., Rose M., Schlueter T., Simoes N.,
RA   Tierrez A., Vazquez-Boland J.-A., Voss H., Wehland J., Cossart P.;
RT   "Comparative genomics of Listeria species.";
RL   Science 294:849-852(2001).
CC   -!- SIMILARITY: Belongs to the short-chain dehydrogenases/reductases (SDR)
CC       family. {ECO:0000305}.
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DR   EMBL; M67471; AAA25288.1; -; Genomic_DNA.
DR   EMBL; AL591975; CAC98511.1; -; Genomic_DNA.
DR   PIR; AI1128; AI1128.
DR   PIR; B39930; B39930.
DR   RefSeq; NP_463961.1; NC_003210.1.
DR   RefSeq; WP_009931125.1; NZ_CP023861.1.
DR   AlphaFoldDB; P25145; -.
DR   SMR; P25145; -.
DR   STRING; 169963.lmo0432; -.
DR   PaxDb; P25145; -.
DR   EnsemblBacteria; CAC98511; CAC98511; CAC98511.
DR   GeneID; 985147; -.
DR   KEGG; lmo:lmo0432; -.
DR   PATRIC; fig|169963.11.peg.445; -.
DR   eggNOG; COG4221; Bacteria.
DR   HOGENOM; CLU_010194_2_10_9; -.
DR   OMA; EWEQMID; -.
DR   PhylomeDB; P25145; -.
DR   BioCyc; LMON169963:LMO0432-MON; -.
DR   Proteomes; UP000000817; Chromosome.
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   InterPro; IPR020904; Sc_DH/Rdtase_CS.
DR   InterPro; IPR002347; SDR_fam.
DR   Pfam; PF00106; adh_short; 1.
DR   PRINTS; PR00081; GDHRDH.
DR   SUPFAM; SSF51735; SSF51735; 1.
DR   PROSITE; PS00061; ADH_SHORT; 1.
PE   3: Inferred from homology;
KW   Oxidoreductase; Reference proteome.
FT   CHAIN           1..248
FT                   /note="Uncharacterized oxidoreductase Lmo0432"
FT                   /id="PRO_0000054883"
FT   ACT_SITE        154
FT                   /note="Proton acceptor"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU10001"
FT   BINDING         9..33
FT                   /ligand="NADP(+)"
FT                   /ligand_id="ChEBI:CHEBI:58349"
FT                   /evidence="ECO:0000250"
FT   BINDING         141
FT                   /ligand="substrate"
FT                   /evidence="ECO:0000250"
FT   CONFLICT        48
FT                   /note="T -> I (in Ref. 1; AAA25288)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        182
FT                   /note="V -> A (in Ref. 1; AAA25288)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   248 AA;  26821 MW;  50262487D29FD935 CRC64;
     MTIKNKVIII TGASSGIGKA TALLLAEKGA KLVLAARRVE KLEKIVQTIK ANSGEAIFAK
     TDVTKREDNK KLVELAIERY GKVDAIFLNA GIMPNSPLSA LKEDEWEQMI DINIKGVLNG
     IAAVLPSFIA QKSGHIIATS SVAGLKAYPG GAVYGATKWA VRDLMEVLRM ESAQEGTNIR
     TVTIYPAAIN TELLETITDK ETEQGMTSLY KQYGITPDRI ASIVAYAIDQ PEDVNVNEFT
     VGPTSQPW