Y4367_DICDI
ID Y4367_DICDI Reviewed; 271 AA.
AC Q54PR7;
DT 24-MAR-2009, integrated into UniProtKB/Swiss-Prot.
DT 24-MAY-2005, sequence version 1.
DT 25-MAY-2022, entry version 83.
DE RecName: Full=PA-phosphatase related-family protein DDB_G0284367;
GN ORFNames=DDB_G0284367;
OS Dictyostelium discoideum (Slime mold).
OC Eukaryota; Amoebozoa; Evosea; Eumycetozoa; Dictyostelia; Dictyosteliales;
OC Dictyosteliaceae; Dictyostelium.
OX NCBI_TaxID=44689;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AX4;
RX PubMed=15875012; DOI=10.1038/nature03481;
RA Eichinger L., Pachebat J.A., Gloeckner G., Rajandream M.A., Sucgang R.,
RA Berriman M., Song J., Olsen R., Szafranski K., Xu Q., Tunggal B.,
RA Kummerfeld S., Madera M., Konfortov B.A., Rivero F., Bankier A.T.,
RA Lehmann R., Hamlin N., Davies R., Gaudet P., Fey P., Pilcher K., Chen G.,
RA Saunders D., Sodergren E.J., Davis P., Kerhornou A., Nie X., Hall N.,
RA Anjard C., Hemphill L., Bason N., Farbrother P., Desany B., Just E.,
RA Morio T., Rost R., Churcher C.M., Cooper J., Haydock S., van Driessche N.,
RA Cronin A., Goodhead I., Muzny D.M., Mourier T., Pain A., Lu M., Harper D.,
RA Lindsay R., Hauser H., James K.D., Quiles M., Madan Babu M., Saito T.,
RA Buchrieser C., Wardroper A., Felder M., Thangavelu M., Johnson D.,
RA Knights A., Loulseged H., Mungall K.L., Oliver K., Price C., Quail M.A.,
RA Urushihara H., Hernandez J., Rabbinowitsch E., Steffen D., Sanders M.,
RA Ma J., Kohara Y., Sharp S., Simmonds M.N., Spiegler S., Tivey A.,
RA Sugano S., White B., Walker D., Woodward J.R., Winckler T., Tanaka Y.,
RA Shaulsky G., Schleicher M., Weinstock G.M., Rosenthal A., Cox E.C.,
RA Chisholm R.L., Gibbs R.A., Loomis W.F., Platzer M., Kay R.R.,
RA Williams J.G., Dear P.H., Noegel A.A., Barrell B.G., Kuspa A.;
RT "The genome of the social amoeba Dictyostelium discoideum.";
RL Nature 435:43-57(2005).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Multi-pass membrane
CC protein {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the PA-phosphatase related phosphoesterase
CC family. {ECO:0000305}.
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DR EMBL; AAFI02000064; EAL65232.1; -; Genomic_DNA.
DR RefSeq; XP_638587.1; XM_633495.1.
DR AlphaFoldDB; Q54PR7; -.
DR SMR; Q54PR7; -.
DR STRING; 44689.DDB0232326; -.
DR PaxDb; Q54PR7; -.
DR EnsemblProtists; EAL65232; EAL65232; DDB_G0284367.
DR GeneID; 8624559; -.
DR KEGG; ddi:DDB_G0284367; -.
DR dictyBase; DDB_G0284367; -.
DR eggNOG; KOG3030; Eukaryota.
DR HOGENOM; CLU_021458_5_1_1; -.
DR InParanoid; Q54PR7; -.
DR OMA; TAPMFFI; -.
DR PhylomeDB; Q54PR7; -.
DR Reactome; R-DDI-1660661; Sphingolipid de novo biosynthesis.
DR Reactome; R-DDI-2029485; Role of phospholipids in phagocytosis.
DR Reactome; R-DDI-419408; Lysosphingolipid and LPA receptors.
DR PRO; PR:Q54PR7; -.
DR Proteomes; UP000002195; Chromosome 4.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0008195; F:phosphatidate phosphatase activity; IBA:GO_Central.
DR GO; GO:0006644; P:phospholipid metabolic process; IEA:InterPro.
DR InterPro; IPR036938; P_Acid_Pase_2/haloperoxi_sf.
DR InterPro; IPR000326; P_Acid_Pase_2/haloperoxidase.
DR InterPro; IPR043216; PA_PP_rel.
DR PANTHER; PTHR10165; PTHR10165; 1.
DR Pfam; PF01569; PAP2; 1.
DR SMART; SM00014; acidPPc; 1.
DR SUPFAM; SSF48317; SSF48317; 1.
PE 3: Inferred from homology;
KW Hydrolase; Membrane; Reference proteome; Transmembrane;
KW Transmembrane helix.
FT CHAIN 1..271
FT /note="PA-phosphatase related-family protein DDB_G0284367"
FT /id="PRO_0000367486"
FT TRANSMEM 23..43
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 68..88
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 102..122
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 150..170
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 181..201
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 211..231
FT /note="Helical"
FT /evidence="ECO:0000255"
SQ SEQUENCE 271 AA; 30533 MW; 9896DAC0937DD9E6 CRC64;
MIHRVSFYGK TTWFTKQHLI DWFLCLGIFV IESVLFNFVI PPFKRYEPES NISTNTFQLV
QYPLLPDIVP VWLLMLIALG LPMVVFIGYY IKNRNSHDFH HAALGLFQAF TITMLFTDIL
KVSAGRYRPD YGARVATGIE AVIREGRVSF PSGHSSVSFC GMTFLSFYLC GKTKVFLKDG
GNILKALVCL CPFMISALVA VSRTVDYHHD FSDILAGSVI GLSIGVFVYF MNFNSLFSKE
CSLPKNRINP HYARDGLLSA EYQSLSISSS L
