ID   Y437_BUCAP              Reviewed;         283 AA.
AC   Q8K9B1;
DT   15-NOV-2002, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-2002, sequence version 1.
DT   03-AUG-2022, entry version 106.
DE   RecName: Full=Uncharacterized MscS family protein BUsg_437;
GN   OrderedLocusNames=BUsg_437;
OS   Buchnera aphidicola subsp. Schizaphis graminum (strain Sg).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Erwiniaceae; Buchnera.
OX   NCBI_TaxID=198804;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Sg;
RX   PubMed=12089438; DOI=10.1126/science.1071278;
RA   Tamas I., Klasson L., Canbaeck B., Naeslund A.K., Eriksson A.-S.,
RA   Wernegreen J.J., Sandstroem J.P., Moran N.A., Andersson S.G.E.;
RT   "50 million years of genomic stasis in endosymbiotic bacteria.";
RL   Science 296:2376-2379(2002).
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the MscS (TC 1.A.23) family. {ECO:0000305}.
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DR   EMBL; AE013218; AAM67980.1; -; Genomic_DNA.
DR   RefSeq; WP_011053947.1; NC_004061.1.
DR   AlphaFoldDB; Q8K9B1; -.
DR   SMR; Q8K9B1; -.
DR   STRING; 198804.BUsg_437; -.
DR   EnsemblBacteria; AAM67980; AAM67980; BUsg_437.
DR   KEGG; bas:BUsg_437; -.
DR   eggNOG; COG0668; Bacteria.
DR   HOGENOM; CLU_037945_1_1_6; -.
DR   OMA; GMQDTLT; -.
DR   OrthoDB; 1903165at2; -.
DR   Proteomes; UP000000416; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0008381; F:mechanosensitive ion channel activity; IEA:InterPro.
DR   Gene3D; 2.30.30.60; -; 1.
DR   InterPro; IPR010920; LSM_dom_sf.
DR   InterPro; IPR045275; MscS_archaea/bacteria_type.
DR   InterPro; IPR006685; MscS_channel.
DR   InterPro; IPR011066; MscS_channel_C.
DR   InterPro; IPR006686; MscS_channel_CS.
DR   InterPro; IPR011014; MscS_channel_TM-2.
DR   InterPro; IPR023408; MscS_dom_sf.
DR   InterPro; IPR008910; TM_helix.
DR   PANTHER; PTHR30221; PTHR30221; 1.
DR   Pfam; PF00924; MS_channel; 1.
DR   Pfam; PF05552; TM_helix; 1.
DR   SUPFAM; SSF50182; SSF50182; 1.
DR   SUPFAM; SSF82689; SSF82689; 1.
DR   SUPFAM; SSF82861; SSF82861; 1.
DR   PROSITE; PS01246; UPF0003; 1.
PE   3: Inferred from homology;
KW   Cell membrane; Membrane; Transmembrane; Transmembrane helix.
FT   CHAIN           1..283
FT                   /note="Uncharacterized MscS family protein BUsg_437"
FT                   /id="PRO_0000110247"
FT   TRANSMEM        24..44
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        64..84
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        96..116
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   283 AA;  31428 MW;  202369E202D600A3 CRC64;
     MNELNVVNDI NHAGNWLIRN QELLFGYVIN LTSAIIILIS GMFIAKIISN GVNQILITRH
     IDATIAGFLS ALMRYIIITF TLIASLGRIG VQTTSVIAIL GAAGMAIGLA LQGSLSNFAA
     GVLLVTLRPL KTGEYVNLGN VAGTVLNIHI FYTTLRTLDG KIVVVPNNKI ISGNIINYSR
     EPARRNEFSI SVSYNTDIDL VIKVLKRVIE NEDRVMKDRD IVIGLSELAP SSLNFIIRCW
     SSTDELNAVY WDLMVKFKKE LDKNNINIPY PQIDVHLYKK NKN