ID   Y4386_RHILO             Reviewed;         309 AA.
AC   Q98E66;
DT   21-FEB-2002, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-2001, sequence version 1.
DT   25-MAY-2022, entry version 92.
DE   RecName: Full=UPF0187 protein mll4386;
GN   OrderedLocusNames=mll4386;
OS   Mesorhizobium japonicum (strain LMG 29417 / CECT 9101 / MAFF 303099)
OS   (Mesorhizobium loti (strain MAFF 303099)).
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Hyphomicrobiales;
OC   Phyllobacteriaceae; Mesorhizobium.
OX   NCBI_TaxID=266835;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=LMG 29417 / CECT 9101 / MAFF 303099;
RX   PubMed=11214968; DOI=10.1093/dnares/7.6.331;
RA   Kaneko T., Nakamura Y., Sato S., Asamizu E., Kato T., Sasamoto S.,
RA   Watanabe A., Idesawa K., Ishikawa A., Kawashima K., Kimura T., Kishida Y.,
RA   Kiyokawa C., Kohara M., Matsumoto M., Matsuno A., Mochizuki Y.,
RA   Nakayama S., Nakazaki N., Shimpo S., Sugimoto M., Takeuchi C., Yamada M.,
RA   Tabata S.;
RT   "Complete genome structure of the nitrogen-fixing symbiotic bacterium
RT   Mesorhizobium loti.";
RL   DNA Res. 7:331-338(2000).
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the UPF0187 family. {ECO:0000305}.
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DR   EMBL; BA000012; BAB51054.1; -; Genomic_DNA.
DR   AlphaFoldDB; Q98E66; -.
DR   SMR; Q98E66; -.
DR   STRING; 266835.14024451; -.
DR   EnsemblBacteria; BAB51054; BAB51054; BAB51054.
DR   KEGG; mlo:mll4386; -.
DR   eggNOG; COG3781; Bacteria.
DR   HOGENOM; CLU_029790_4_2_5; -.
DR   OMA; TDICGAC; -.
DR   Proteomes; UP000000552; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0005254; F:chloride channel activity; IEA:InterPro.
DR   InterPro; IPR021134; Bestrophin/UPF0187.
DR   InterPro; IPR044669; UPF0187.
DR   PANTHER; PTHR33281; PTHR33281; 1.
DR   Pfam; PF01062; Bestrophin; 1.
PE   3: Inferred from homology;
KW   Cell membrane; Membrane; Transmembrane; Transmembrane helix.
FT   CHAIN           1..309
FT                   /note="UPF0187 protein mll4386"
FT                   /id="PRO_0000217668"
FT   TRANSMEM        27..49
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        59..78
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        226..248
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   309 AA;  34543 MW;  F3009098531D325D CRC64;
     MPVRERPSMI VRPRPNFLQL FFIMRGSVVP RILPQIFGFA VYSAVILALA RWFELDLGVF
     NITPFGLVGV TLSIYLSFRN NAAYDRWWEA RKLWGTLVFE IRNLARATTS LIPDPAEQRA
     LLMEALAFCH FLRGQLRKTD SIKDARAFID AQAETVAGFA NPADEMVRRM GRRANAQRRA
     GDVDPIGFRI LDERLASITA IQAGCERIAG TPLPFAYTLL VHRTAYIVCL LLPIGLISTT
     GWATPLFTAL IAYTFFGLDA LSEELEDPFG TEANDLALDG LCRVCEISVF EALGEAPPKM
     LPAEKFYFS