ID   Y4428_SALTY             Reviewed;         388 AA.
AC   Q8ZK55;
DT   10-JAN-2003, integrated into UniProtKB/Swiss-Prot.
DT   01-MAR-2002, sequence version 1.
DT   03-AUG-2022, entry version 99.
DE   RecName: Full=Uncharacterized MFS-type transporter STM4428 {ECO:0000305};
GN   OrderedLocusNames=STM4428;
OS   Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Salmonella.
OX   NCBI_TaxID=99287;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=LT2 / SGSC1412 / ATCC 700720;
RX   PubMed=11677609; DOI=10.1038/35101614;
RA   McClelland M., Sanderson K.E., Spieth J., Clifton S.W., Latreille P.,
RA   Courtney L., Porwollik S., Ali J., Dante M., Du F., Hou S., Layman D.,
RA   Leonard S., Nguyen C., Scott K., Holmes A., Grewal N., Mulvaney E.,
RA   Ryan E., Sun H., Florea L., Miller W., Stoneking T., Nhan M., Waterston R.,
RA   Wilson R.K.;
RT   "Complete genome sequence of Salmonella enterica serovar Typhimurium LT2.";
RL   Nature 413:852-856(2001).
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000255|HAMAP-
CC       Rule:MF_02091}; Multi-pass membrane protein {ECO:0000255|HAMAP-
CC       Rule:MF_02091}.
CC   -!- SIMILARITY: Belongs to the major facilitator superfamily. YfcJ family.
CC       {ECO:0000255|HAMAP-Rule:MF_02091}.
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DR   EMBL; AE006468; AAL23248.1; -; Genomic_DNA.
DR   RefSeq; NP_463289.1; NC_003197.2.
DR   RefSeq; WP_001111174.1; NC_003197.2.
DR   AlphaFoldDB; Q8ZK55; -.
DR   SMR; Q8ZK55; -.
DR   PaxDb; Q8ZK55; -.
DR   EnsemblBacteria; AAL23248; AAL23248; STM4428.
DR   GeneID; 1255954; -.
DR   KEGG; stm:STM4428; -.
DR   PATRIC; fig|99287.12.peg.4656; -.
DR   HOGENOM; CLU_001265_10_3_6; -.
DR   OMA; GSTLWGM; -.
DR   PhylomeDB; Q8ZK55; -.
DR   BioCyc; SENT99287:STM4428-MON; -.
DR   Proteomes; UP000001014; Chromosome.
DR   GO; GO:0005887; C:integral component of plasma membrane; IEA:UniProtKB-UniRule.
DR   GO; GO:0022857; F:transmembrane transporter activity; IEA:UniProtKB-UniRule.
DR   Gene3D; 1.20.1250.20; -; 1.
DR   HAMAP; MF_02091; MFS_YfcJ; 1.
DR   InterPro; IPR011701; MFS.
DR   InterPro; IPR020846; MFS_dom.
DR   InterPro; IPR036259; MFS_trans_sf.
DR   InterPro; IPR037541; MFS_YfcJ.
DR   Pfam; PF07690; MFS_1; 2.
DR   SUPFAM; SSF103473; SSF103473; 1.
DR   PROSITE; PS50850; MFS; 1.
PE   3: Inferred from homology;
KW   Cell inner membrane; Cell membrane; Membrane; Reference proteome;
KW   Transmembrane; Transmembrane helix; Transport.
FT   CHAIN           1..388
FT                   /note="Uncharacterized MFS-type transporter STM4428"
FT                   /id="PRO_0000087814"
FT   TRANSMEM        18..38
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_02091"
FT   TRANSMEM        42..62
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_02091"
FT   TRANSMEM        89..111
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_02091"
FT   TRANSMEM        116..136
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_02091"
FT   TRANSMEM        145..165
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_02091"
FT   TRANSMEM        171..191
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_02091"
FT   TRANSMEM        219..239
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_02091"
FT   TRANSMEM        248..268
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_02091"
FT   TRANSMEM        287..307
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_02091"
FT   TRANSMEM        341..361
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_02091"
FT   TRANSMEM        365..385
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_02091"
SQ   SEQUENCE   388 AA;  40695 MW;  6BF80E043E67A35D CRC64;
     MPALTQHSTS ITLFRISAAM FLNYLTIGIP LVMLPLYVQQ QLHLSDLLIG IAVGSQFIAT
     LLTRGAAGRK ADTSGGRRTV ITGQFYCAAS GLLMLVSLIA HPVPLLAWAI LIVGRVLLGI
     GESFILTGNL TWGMWLAGST HAGQVISWNG MATYGALAIG APLGLSLYAR AGLALPALLV
     VLLPIIASGV IYGIPGNIPT ARPRVPVLRV VGLVWRPGTG LVLQGIGFAT LSAFTALWFN
     ERHWDNTGFA MTLFGIAFIA VRFFCAKFPD RYGGATVATF SLLVEGTGLA VMWAAPSAGA
     ALIGAAITGC GCSLMFPSLG VEVVRRVPPE IRGTALGVWS AFQDLAYGFT GPIAGLLTPF
     IGYQQVFLLA AACALLGAAV VHLLLRQH