ID   Y443_MYCGE              Reviewed;         395 AA.
AC   P47681;
DT   01-OCT-1996, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-1996, sequence version 1.
DT   03-AUG-2022, entry version 103.
DE   RecName: Full=Uncharacterized protein MG443;
GN   OrderedLocusNames=MG443;
OS   Mycoplasma genitalium (strain ATCC 33530 / DSM 19775 / NCTC 10195 / G37)
OS   (Mycoplasmoides genitalium).
OC   Bacteria; Tenericutes; Mollicutes; Mycoplasmataceae; Mycoplasma.
OX   NCBI_TaxID=243273;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 33530 / DSM 19775 / NCTC 10195 / G37;
RX   PubMed=7569993; DOI=10.1126/science.270.5235.397;
RA   Fraser C.M., Gocayne J.D., White O., Adams M.D., Clayton R.A.,
RA   Fleischmann R.D., Bult C.J., Kerlavage A.R., Sutton G.G., Kelley J.M.,
RA   Fritchman J.L., Weidman J.F., Small K.V., Sandusky M., Fuhrmann J.L.,
RA   Nguyen D.T., Utterback T.R., Saudek D.M., Phillips C.A., Merrick J.M.,
RA   Tomb J.-F., Dougherty B.A., Bott K.F., Hu P.-C., Lucier T.S.,
RA   Peterson S.N., Smith H.O., Hutchison C.A. III, Venter J.C.;
RT   "The minimal gene complement of Mycoplasma genitalium.";
RL   Science 270:397-403(1995).
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
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DR   EMBL; L43967; AAC72463.1; -; Genomic_DNA.
DR   PIR; I64248; I64248.
DR   RefSeq; WP_010869483.1; NC_000908.2.
DR   AlphaFoldDB; P47681; -.
DR   STRING; 243273.MG_443; -.
DR   EnsemblBacteria; AAC72463; AAC72463; MG_443.
DR   KEGG; mge:MG_443; -.
DR   eggNOG; COG1284; Bacteria.
DR   HOGENOM; CLU_043038_0_0_14; -.
DR   OMA; VYSHKME; -.
DR   OrthoDB; 1265821at2; -.
DR   BioCyc; MGEN243273:G1GJ2-536-MON; -.
DR   Proteomes; UP000000807; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   Gene3D; 3.30.70.120; -; 1.
DR   InterPro; IPR019264; DUF2179.
DR   InterPro; IPR015867; N-reg_PII/ATP_PRibTrfase_C.
DR   InterPro; IPR003740; YitT.
DR   Pfam; PF10035; DUF2179; 1.
DR   Pfam; PF02588; YitT_membrane; 1.
PE   4: Predicted;
KW   Cell membrane; Membrane; Reference proteome; Transmembrane;
KW   Transmembrane helix.
FT   CHAIN           1..395
FT                   /note="Uncharacterized protein MG443"
FT                   /id="PRO_0000210616"
FT   TRANSMEM        42..62
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        67..87
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        97..117
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        128..148
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        196..216
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        241..261
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        281..301
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   395 AA;  44659 MW;  DAF03CCE62686C2E CRC64;
     MKFFNNLFKK ESKITVASGS KRVRISNSFL MFSNLYEAKK PLKYVLVYLL SIINAFLLLI
     FIQKTGLYSF GISSLTQGFA RLVFVLLKSF DETQRLLIFN ILYWLLYVFI NIPLIIFSYK
     KIGKNFTILS THFVVASNVF GFLISIIPGS DNLPPMLASI TDTNFWKAAK DLNQSAGFVP
     FLWSDTSQGN VIISTFIYAA IYGFYNGISV SLLYILGGSA GGADFLTQYY ARKKNRSVGS
     ILFYVNSFIL IIAILIGSFV AGSLLLQDVN NYRDSAWEVS LFFSPNLIAT FFSILLTGTV
     VSYLFPRYNF AEIKVFTDKL EEVRKALLSD NANHSLSIQE TLGGYSLLKK KMIVSVSMYV
     EIPHLIKIIR QIDKDCLVSI TRIRGIDGHI YLRQN